Search Results - "PRUSS, Axel"

Riboflavin: The Health Benefits of a Forgotten Natural Vitamin by Suwannasom, Nittiya, Kao, Ijad, Pruß, Axel, Georgieva, Radostina, Bäumler, Hans

“…Riboflavin (RF) is a water-soluble member of the B-vitamin family. Sufficient dietary and supplemental RF intake appears to have a protective effect on various…”
Get full text

HLA in Transplantation: Challenges and Perspectives by Lachmann, Nils, Pruß, Axel

Get full text

Three different pathways of IgM-antibody-dependent hemolysis are mainly regulated by complement by Bartolmäs, Thilo, Pruß, Axel, Mayer, Beate

“…Antibodies to red blood cells (RBCs) may hemolyze erythrocytes Fc-mediated phagocytosis or complement-dependent. Complement activation on RBCs can be detected…”
Get full text

Combining different CRISPR nucleases for simultaneous knock-in and base editing prevents translocations in multiplex-edited CAR T cells by Glaser, Viktor, Flugel, Christian, Kath, Jonas, Du, Weijie, Drosdek, Vanessa, Franke, Clemens, Stein, Maik, Pruß, Axel, Schmueck-Henneresse, Michael, Volk, Hans-Dieter, Reinke, Petra, Wagner, Dimitrios L

“…Multiple genetic modifications may be required to develop potent off-the-shelf chimeric antigen receptor (CAR) T cell therapies. Conventional CRISPR-Cas…”
Get full text

Coding of Tissue and Cell Products by Pruß, Axel

Get full text

Safety Aspects in Tissue Banking – An Update by Pruß, Axel, Schroeter, Jan

Get full text

Disease Severity, Fever, Age, and Sex Correlate With SARS-CoV-2 Neutralizing Antibody Responses by Schlickeiser, Stephan, Schwarz, Tatjana, Steiner, Sophie, Wittke, Kirsten, Al Besher, Nabeel, Meyer, Oliver, Kalus, Ulrich, Pruß, Axel, Kurth, Florian, Zoller, Thomas, Witzenrath, Martin, Sander, Leif Erik, Müller, Marcel A, Scheibenbogen, Carmen, Volk, Hans-Dieter, Drosten, Christian, Corman, Victor M, Hanitsch, Leif G

“…Clinical trials on the use of COVID-19 convalescent plasma remain inconclusive. While data on safety is increasingly available, evidence for efficacy is still…”
Get full text

Positive Long-Term Outcome of Kidney Allocation via Acceptable Mismatch Program in Highly Sensitized Patients by Strehler, Yara, Lachmann, Nils, Niemann, Matthias, Halleck, Fabian, Budde, Klemens, Pruß, Axel

“…Abstract Introduction: Eurotransplant established the acceptable mismatch (AM) program to facilitate timely kidney transplantations of highly sensitized…”
Get full text

Human platelet-rich plasma stimulates migration and chondrogenic differentiation of human subchondral progenitor cells by Krüger, Jan Philipp, Hondke, Sylvia, Endres, Michaela, Pruss, Axel, Siclari, Alberto, Kaps, Christian

“…In cartilage repair, platelet‐rich plasma (PRP) is used in one‐step approaches utilizing microfracture and matrix‐induced chondrogenesis procedures, bone…”
Get full text

Platelet-Rich Plasma Preparation Types Show Impact on Chondrogenic Differentiation, Migration, and Proliferation of Human Subchondral Mesenchymal Progenitor Cells by Kreuz, Peter Cornelius, M.D, Krüger, Jan Philipp, Ph.D, Metzlaff, Sebastian, M.D, Freymann, Undine, Ph.D, Endres, Michaela, Ph.D, Pruss, Axel, M.D, Petersen, Wolf, M.D, Kaps, Christian, Ph.D

“…Purpose To evaluate the chondrogenic potential of platelet concentrates on human subchondral mesenchymal progenitor cells (MPCs) as assessed by…”
Get full text

Validation of Microbiological Testing of Tissue Preparations with Different Incubation Temperatures by Herrlinger, Frithjof, Schulz, Tino, Pruß, Axel, Schulz, Eva

“…Introduction: The European Pharmacopoeia (Ph. Eur.) provides principles for microbiological testing of tissue preparations. According to the Ph. Eur., tests…”
Get full text

Comparative Analysis of Different Platelet Lysates and Platelet Rich Preparations to Stimulate Tendon Cell Biology: An In Vitro Study by Klatte-Schulz, Franka, Schmidt, Tanja, Uckert, Melanie, Scheffler, Sven, Kalus, Ulrich, Rojewski, Markus, Schrezenmeier, Hubert, Pruss, Axel, Wildemann, Britt

“…The poor healing potential of tendons is still a clinical problem, and the use of Platelet Rich Plasma (PRP) was hypothesized to stimulate healing. As the…”
Get full text

Rituximab therapy after pediatric hematopoietic stem cell transplantation can cause prolonged B-cell impairment and increases the risk for infections - a retrospective matched cohort study by Launspach, Michael, Temel, Dennis, Ohlendorf, Emily, Zirngibl, Felix, Materne, Bianca, Oevermann, Lena, Deubzer, Hedwig E, Henssen, Anton G, Künkele, Annette, Hundsdörfer, Patrick, Bernuth, Horst von, Pruß, Axel, Eggert, Angelika, Stackelberg, Arend von, Lang, Peter, Schulte, Johannes H

Get full text

Integration of ζ-deficient CARs into the CD3ζ gene conveys potent cytotoxicity in T and NK cells by Kath, Jonas, Franke, Clemens, Drosdek, Vanessa, Du, Weijie, Glaser, Viktor, Fuster-Garcia, Carla, Stein, Maik, Zittel, Tatiana, Schulenberg, Sarah, Porter, Caroline E., Andersch, Lena, Künkele, Annette, Alcaniz, Joshua, Hoffmann, Jens, Abken, Hinrich, Abou-el-Enein, Mohamed, Pruß, Axel, Suzuki, Masataka, Cathomen, Toni, Stripecke, Renata, Volk, Hans-Dieter, Reinke, Petra, Schmueck-Henneresse, Michael, Wagner, Dimitrios L.

“…•Integration of ζ-deficient CARs into the CD3ζ gene allows generation of functional TCR-ablated CAR-T cells for allogeneic off-the-shelf use.•CD3ζ-editing…”
Get full text

Determination of Methemoglobin in Hemoglobin Submicron Particles Using NMR Relaxometry by Kaewprayoon, Waraporn, Suwannasom, Nittiya, Kloypan, Chiraphat, Steffen, Axel, Xiong, Yu, Schellenberger, Eyk, Pruß, Axel, Georgieva, Radostina, Bäumler, Hans

“…Methemoglobin (MetHb) is a hemoglobin (Hb) derivative with the heme iron in ferric state (Fe ), unable to deliver oxygen. Quantification of methemoglobin is a…”
Get full text

Transfusion of red blood cells does not impact progression‐free and overall survival after surgery for ovarian cancer by Hunsicker, Oliver, Gericke, Sara, Graw, Jan Adriaan, Krannich, Alexander, Boemke, Willehad, Meyer, Oliver, Braicu, Ioana, Spies, Claudia, Sehouli, Jalid, Pruß, Axel, Feldheiser, Aarne

“…BACKGROUND Allogeneic red blood cells (RBCs) have the potential to impact the immunosurveillance of the recipient and may therefore increase the risk of…”
Get full text

SARS-CoV-2 T Cell Response in Severe and Fatal COVID-19 in Primary Antibody Deficiency Patients Without Specific Humoral Immunity by Steiner, Sophie, Schwarz, Tatjana, Corman, Victor M, Gebert, Laura, Kleinschmidt, Malte C, Wald, Alexandra, Gläser, Sven, Kruse, Jan M, Zickler, Daniel, Peric, Alexander, Meisel, Christian, Meyer, Tim, Staudacher, Olga L, Wittke, Kirsten, Kedor, Claudia, Bauer, Sandra, Besher, Nabeel Al, Kalus, Ulrich, Pruß, Axel, Drosten, Christian, Volk, Hans-Dieter, Scheibenbogen, Carmen, Hanitsch, Leif G

“…Morbidity and mortality of COVID-19 is increased in patients with inborn errors of immunity (IEI). Age and comorbidities and also impaired type I interferon…”
Get full text

Donor selection in a pediatric stem cell transplantation cohort using PIRCHE and HLA‐DPB1 typing by Stenger, Wiebke, Künkele, Annette, Niemann, Matthias, Todorova, Kremena, Pruß, Axel, Schulte, Johannes H., Eggert, Angelika, Oevermann, Lena

“…Background New strategies to optimize donor selection for hematopoietic stem cell transplantation (HSCT) have mainly been evaluated in adults, but the disease…”
Get full text

Pharmacological interventions enhance virus-free generation of TRAC-replaced CAR T cells by Kath, Jonas, Du, Weijie, Pruene, Alina, Braun, Tobias, Thommandru, Bernice, Turk, Rolf, Sturgeon, Morgan L., Kurgan, Gavin L., Amini, Leila, Stein, Maik, Zittel, Tatiana, Martini, Stefania, Ostendorf, Lennard, Wilhelm, Andreas, Akyüz, Levent, Rehm, Armin, Höpken, Uta E., Pruß, Axel, Künkele, Annette, Jacobi, Ashley M., Volk, Hans-Dieter, Schmueck-Henneresse, Michael, Stripecke, Renata, Reinke, Petra, Wagner, Dimitrios L.

“…Chimeric antigen receptor (CAR) redirected T cells are potent therapeutic options against hematological malignancies. The current dominant manufacturing…”
Get full text

Recognition mechanisms of hemoglobin particles by monocytes – CD163 may just be one by Nimz, Jonathan-Gabriel, Rerkshanandana, Pichayut, Kloypan, Chiraphat, Kalus, Ulrich, Chaiwaree, Saranya, Pruß, Axel, Georgieva, Radostina, Xiong, Yu, Bäumler, Hans

“…Hemoglobin-based oxygen carriers (HBOCs) as blood substitutes are one of the great hopes of modern transfusion and emergency medicine. After the major…”
Get full text