Search Results - "PRUNIER, Chloe"

LIM kinases: cofilin and beyond by Prunier, Chloé, Prudent, Renaud, Kapur, Reuben, Sadoul, Karin, Lafanechère, Laurence

“…LIM kinases are common downstream effectors of several signalization pathways and function as a signaling node that controls cytoskeleton dynamics through the…”
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Procedures and applications of long-term intravital microscopy by Prunier, Chloé, Chen, Na, Ritsma, Laila, Vrisekoop, Nienke

“…•Long-term IVM enables repetitive imaging over days to months within the same animal.•Procedures, Pros & Cons, and Tips & Tricks of different imaging windows…”
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PD-1/PD-L1 Checkpoint Inhibitors Are Active in the Chicken Embryo Model and Show Antitumor Efficacy In Ovo by Wang, Yan, Rousset, Xavier, Prunier, Chloé, Garcia, Paul, Dosda, Emilien, Leplus, Estelle, Viallet, Jean

“…(1) Purpose: To assess the use of the chicken embryo (in ovo) model as an alternative in vivo model for immuno-oncology (IO) drug development, focusing on…”
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Targeting LIM kinases in taxane resistant tumors by Prunier, Chloé, Kapur, Reuben, Lafanechère, Laurence

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Breast cancer dormancy is associated with a 4NG1 state and not senescence by Prunier, Chloé, Alay, Ania, van Dijk, Michiel, Ammerlaan, Kelly L., van Gelderen, Sharon, Marvin, Dieuwke L., Teunisse, Amina, Slieker, Roderick C., Szuhai, Karoly, Jochemsen, A. G., Solé, Xavier, ten Dijke, Peter, Ritsma, Laila

“…Reactivation of dormant cancer cells can lead to cancer relapse, metastasis, and patient death. Dormancy is a nonproliferative state and is linked to late…”
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Two-Photon Intravital Microscopy Animal Preparation Protocol to Study Cellular Dynamics in Pathogenesis by van Grinsven, Erinke, Prunier, Chloé, Vrisekoop, Nienke, Ritsma, Laila

“…Two-photon intravital microscopy (2P-IVM) is an advanced imaging platform that allows the visualization of dynamic processes at subcellular resolution in vivo…”
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Pharmacological Inhibition of LIM Kinase Stabilizes Microtubules and Inhibits Neoplastic Growth by PRUDENT, Renaud, VASSAL-STERMANN, Emilie, VALDAMERI, Glaucio, HONORE, Stéphane, ACI-SECHE, Samia, GRIERSON, David, ANTONIPILLAI, Juliana, RONG LI, DI PIETRO, Attilio, DUMONTET, Charles, BRAGUER, Diane, FLORENT, Jean-Claude, NGUYEN, Chi-Hung, KNAPP, Stefan, BERNARD, Ora, LAFANECHERE, Laurence, PILLET, Catherine, MARTINEZ, Anne, PRUNIER, Chloe, BARETTE, Caroline, SOLEILHAC, Emmanuelle, FILHOL, Odile, BEGHIN, Anne

“…The emergence of tumor resistance to conventional microtubule-targeting drugs restricts their clinical use. Using a cell-based assay that recognizes…”
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LIM Kinase Inhibitor Pyr1 Reduces the Growth and Metastatic Load of Breast Cancers by Prunier, Chloé, Josserand, Véronique, Vollaire, Julien, Beerling, Evelyne, Petropoulos, Christos, Destaing, Olivier, Montemagno, Christopher, Hurbin, Amandine, Prudent, Renaud, de Koning, Leanne, Kapur, Reuben, Cohen, Pascale A, Albiges-Rizo, Corinne, Coll, Jean-Luc, van Rheenen, Jacco, Billaud, Marc, Lafanechère, Laurence

“…LIM kinases (LIMK) are emerging targets for cancer therapy, and they function as network hubs to coordinate actin and microtubule dynamics. When LIMKs are…”
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Effectiveness of Rhenium(I)-diselenoether Low Doses in a Triple-negative Breast Cancer Chicken Embryo Model by Collery, Philippe, Prunier, Chloe, Dosda, Emilien, Viallet, Jean, Harikrishnan, Adhikesavan, Veena, Vijay, Desmaele, Didier

“…Rhenium(I)-diselenoether (Re-diSe) is a promising anticancer agent composed of one rhenium and two selenium atoms. Its effectiveness was established in…”
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Aging and photo-aging DNA repair phenotype of skin cells-evidence toward an effect of chronic sun-exposure by Prunier, Chloé, Masson-Genteuil, Gwénaëlle, Ugolin, Nicolas, Sarrazy, Fanny, Sauvaigo, Sylvie

“…Several studies have demonstrated the deleterious effect of aging on the capacity of cells to repair their DNA. However, current existing assays aimed at…”
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Persistent Properties of a Subpopulation of Cancer Cells Overexpressing the Hedgehog Receptor Patched by Feliz Morel, Álvaro Javier, Hasanovic, Anida, Morin, Aurélie, Prunier, Chloé, Magnone, Virginie, Lebrigand, Kevin, Aouad, Amaury, Cogoluegnes, Sarah, Favier, Judith, Pasquier, Claude, Mus-Veteau, Isabelle

“…Despite the development of new therapeutic strategies, cancer remains one of the leading causes of mortality worldwide. One of the current major challenges is…”
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Abstract 4018: An innovative in vivo model for CAR-T cell therapy development: Tolerability and efficacy evaluation of CD19-targeting CAR-T cells on human lymphoma using the chicken CAM assay by Wang, Yan, Rousset, Xavier, Prunier, Chloé, Dosda, Emilien, Gutierrez-Guerrero, Alejandra, Abrial, Pauline, Menkova, Inna, Viallet, Jean

“…Abstract BACKGROUND Chimeric antigen receptor (CAR) T cell therapy is a revolutionary approach in cellular immunotherapy, where a patient’s T cells are…”
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LIM Kinases: cofilin and beyond by Prunier, Chloé, Prudent, Renaud, Kapur, Reuben, Sadoul, Karin, Lafanechère, Laurence

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Persistent Properties of a Subpopulation of Cancer Cells Overexpressing the Hedgehog Receptor Patched by Feliz Morel, Álvaro Javier, Hasanovic, Anida, Morin, Aurélie, Prunier, Chloé, Magnone, Virginie, Lebrigand, Kevin, Aouad, Amaury, Cogoluegnes, Sarah, Favier, Judith, Pasquier, Claude, Mus-Veteau, Isabelle

“…Despite the development of new therapeutic strategies, cancer remains one of the leading causes of mortality worldwide. One of the current major challenges is…”
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Abstract 5399: Anti-cancer activity of a new LIM-Kinases inhibitor: “LIM-Pyr1” by Prunier, Chloé, Vollaire, Julien, Josserand, Véronique, Zomer, Anoek, Hurbin, Amandine, Prudent, Renaud, Cohen, Pascale, van Rheenen, Jacco, Coll, Jean-Luc, Billaud, Marc, Lafanechère, Laurence

“…Abstract Breast cancer is the second cause of death in Europe with an incidence of 464.00 new cases in 2012. Chemotherapy is frequently used to treat severe…”
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