Search Results - "PROUDFOOT, D."

Post‐translational modifications regulate matrix Gla protein function: importance for inhibition of vascular smooth muscle cell calcification by SCHURGERS, L. J., SPRONK, H. M. H., SKEPPER, J. N., HACKENG, T. M., SHANAHAN, C. M., VERMEER, C., WEISSBERG, P. L., PROUDFOOT, D.

“…Background: Matrix Gla protein (MGP) is a small vitamin K‐dependent protein containing five γ‐carboxyglutamic acid (Gla) residues that are believed to be…”
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Vascular smooth muscle cell phenotypic plasticity and the regulation of vascular calcification by IYEMERE, V. P., PROUDFOOT, D., WEISSBERG, P. L., SHANAHAN, C. M.

“… Vascular smooth muscle cells (VSMCs) exhibit an extraordinary capacity to undergo phenotypic change during development, in vitro and in association with…”
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Calcification stimulates inflammatory signalling pathways in human vascular smooth muscle cells by Proudfoot, D, Dautova, Y, Kozlova, D, Epple, M, Bootman, M.D

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Nox5 Regulates Vascular Smooth Muscle Cell Phenotype by Furmanik, G., Chatrou, M., Willems, B., van Gorp, R., Schmidt, H., van Eys, G., Bochaton-Piallat, M.L., Proudfoot, D., Biessen, E., Hedin, U., Matic, L. Perisic, Mees, B., Shanahan, C., Reutelingsperger, C., Schurgers, L.

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Acetylated low-density lipoprotein stimulates human vascular smooth muscle cell calcification by promoting osteoblastic differentiation and inhibiting phagocytosis by PROUDFOOT, D, DAVIES, J. D, SKEPPER, J. N, WEISSBERG, P. L, SHANAHAN, C. M

“…Vascular smooth muscle cells (VSMCs) in atherosclerotic lesions display an osteogenic phenotype, and calcification commonly occurs in association with lipid…”
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Leflunomide in rheumatoid arthritis: recommendations through a process of consensus by Maddison, P., Kiely, P., Kirkham, B., Lawson, T., Moots, R., Proudfoot, D., Reece, R., Scott, D., Sword, R., Taggart, A., Thwaites, C., Williams, E.

“…Objectives. To determine, by consensus, the optimal use of leflunomide in rheumatoid arthritis (RA), using a multidisciplinary panel of experts and performing…”
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Vascular and valvar calcification: recent advances by Farzaneh-Far, A, Proudfoot, D, Shanahan, C, Weissberg, P L

“…There is evidence that alterations in calcification regulatory proteins and change to an osteogenic phenotype occur in an analogous fashion to vascular…”
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The role of apoptosis in the initiation of vascular calcification by Proudfoot, D, Skepper, J N, Hegyi, L, Farzaneh-Far, A, Shanahan, C M, Weissberg, P L

“…The initiation sites for calcification in cartilage and bone are cellular products called matrix vesicles. Similar structures have been found in calcified…”
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Vascular calcification: new insights into an old problem by Proudfoot, Diane, Shanahan, Catherine M., Weissberg, Peter L.

“…This review covers the pathology of intimal and medial vascular calcification and discusses the molecular mechanisms of vascular calcification in light of…”
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Facts about Artificial Intelligence by Proudfoot, Diane

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High adenoviral loads stimulate NFκB-dependent gene expression in human vascular smooth muscle cells by CLESHAM, G. J, ADAM, P. J, PROUDFOOT, D, FLYNN, P. D, EFSTATHIOU, S, WEISSBERG, P. L

“…Replication-deficient adenoviral vectors have been widely used for gene transfer with the aim of delivering genes of interest to investigate their function and…”
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On Wittgenstein on Cognitive Science by Proudfoot, D.

“…Cognitive science is held, not only by its practitioners, to offer something distinctively new in the philosophy of mind. This novelty is seen as the product…”
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Reactive Oxygen-Forming Nox5 Links Vascular Smooth Muscle Cell Phenotypic Switching and Extracellular Vesicle-Mediated Vascular Calcification by Furmanik, Malgorzata, Chatrou, Martijn, van Gorp, Rick, Akbulut, Asim, Willems, Brecht, Schmidt, Harald, van Eys, Guillaume, Bochaton-Piallat, Marie-Luce, Proudfoot, Diane, Biessen, Erik, Hedin, Ulf, Perisic, Ljubica, Mees, Barend, Shanahan, Catherine, Reutelingsperger, Chris, Schurgers, Leon

“…RATIONALE:Vascular calcification, the formation of calcium phosphate crystals in the vessel wall, is mediated by vascular smooth muscle cells (VSMCs). However,…”
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Transcriptional regulation of matrix gla protein by Farzaneh-Far, A, Weissberg, P L, Proudfoot, D, Shanahan, C M

“…Matrix Gla Protein (MGP) is a small protein which is thought to be an inhibitor of tissue calcification and a regulator of cell differentiation. In this study…”
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Monocyte prostaglandins inhibit procollagen secretion by human vascular smooth muscle cells: implications for plaque stability by Fitzsimmons, C., Proudfoot, D., Bowyer, D.E.

“…Extracellular matrix remodelling occurs during atherosclerosis dictating the structure of the plaque and thus the resistance to rupture. Monocytes and…”
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Inhibition of human arterial smooth muscle cell growth by human monocyte/macrophages: a co-culture study by Proudfoot, D, Fitzsimmons, C, Torzewski, J, Bowyer, D.E

“…Monocyte/macrophages produce a variety of substances which may influence the function of smooth muscle cells (SMC). During atherogenesis, macrophages are…”
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Coronary artery inflammatory biomarker expression does not correlate with systemic elevation of biomarkers or of HSCRP by West, N., Corrigan, J., Brown, A., Owen, R., Hoole, S., Blatcher, S., Proudfoot, D.

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Mobile intracardiac calcinosis: risk of thromboembolism in patients with haemodialysed end stage renal disease by FARZANEH-FAR, A, SHANAHAN, C, PROUDFOOT, D, WEISSBERG, PL

“…[...]warfarin use will not be the main cause of rapid calcinosis, at least in our series of cases. [...]in case 2 of our study, 1-6 a surgical specimen…”
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Human vascular smooth muscle cells undergo vesicle-mediated calcification in response to changes in extracellular calcium and phosphate concentrations: A potential mechanism for accelerated vascular calcification in ESRD by REYNOLDS, Joanne L, JOANNIDES, Alexis J, SKEPPER, Jeremy N, MCNAIR, Rosamund, SCHURGERS, Leon J, PROUDFOOT, Diane, JAHNEN-DECHENT, Willi, WEISSBERG, Peter L, SHANAHAN, Catherine M

“…Patients with ESRD have a high circulating calcium (Ca) x phosphate (P) product and develop extensive vascular calcification that may contribute to their high…”
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Temporal parts and their individuation by Copeland, Jack, Dyke, Heather, Proudfoot, Diane

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