Search Results - "PRITCHARD, L"

Identifying neoantigens for use in immunotherapy by Hutchison, Sharon, Pritchard, Antonia L.

“…This review focuses on the types of cancer antigens that can be recognised by the immune system and form due to alterations in the cancer genome, including…”
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Processing of proglucagon to GLP-1 in pancreatic α-cells: is this a paracrine mechanism enabling GLP-1 to act on β-cells? by Whalley, N M, Pritchard, L E, Smith, D M, White, A

“…Proglucagon is cleaved to glucagon by prohormone convertase 2 (PC2) in pancreatic α-cells, but is cleaved to glucagon-like peptide-1 (GLP-1) by PC1 in…”
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Integrative Taxonomy Recognizes Evolutionary Units Despite Widespread Mitonuclear Discordance: Evidence from a Rotifer Cryptic Species Complex by Papakostas, Spiros, Michaloudi, Evangelia, Proios, Konstantinos, Brehm, Michaela, Verhage, Laurens, Rota, Jadranka, Peña, Carlos, Stamou, Georgia, Pritchard, Victoria L., Fontaneto, Diego, Declerck, Steven A.J.

“…Mitonuclear discordance across taxa is increasingly recognized as posing a major challenge to species delimitation based on DNA sequence data. Integrative…”
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Using Tablet for visual exploration of second-generation sequencing data by Milne, Iain, Stephen, Gordon, Bayer, Micha, Cock, Peter J A, Pritchard, Leighton, Cardle, Linda, Shaw, Paul D, Marshall, David

“…The advent of second-generation sequencing (2GS) has provided a range of significant new challenges for the visualization of sequence assemblies. These include…”
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POT1 loss-of-function variants predispose to familial melanoma by Robles-Espinoza, Carla Daniela, Harland, Mark, Ramsay, Andrew J, Aoude, Lauren G, Quesada, Víctor, Ding, Zhihao, Pooley, Karen A, Pritchard, Antonia L, Tiffen, Jessamy C, Petljak, Mia, Palmer, Jane M, Symmons, Judith, Johansson, Peter, Stark, Mitchell S, Gartside, Michael G, Snowden, Helen, Montgomery, Grant W, Martin, Nicholas G, Liu, Jimmy Z, Choi, Jiyeon, Makowski, Matthew, Brown, Kevin M, Dunning, Alison M, Keane, Thomas M, López-Otín, Carlos, Gruis, Nelleke A, Hayward, Nicholas K, Bishop, D Timothy, Newton-Bishop, Julia A, Adams, David J

“…David Adams, Julia Newton-Bishop, Timothy Bishop, Nicholas Hayward and colleagues identify loss-of-function variants in POT1 in several families with early…”
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Anti-RhoA and Anti-RhoC siRNAs Inhibit the Proliferation and Invasiveness of MDA-MB-231 Breast Cancer Cells in Vitro and in Vivo by Pillé, J.-Y., Denoyelle, C., Varet, J., Bertrand, J.-R., Soria, J., Opolon, P., Lu, H., Pritchard, L.-L., Vannier, J.-P., Malvy, C., Soria, C., Li, H.

“…Overexpression of RhoA or RhoC in breast cancer indicates a poor prognosis, due to increased tumor cell proliferation and invasion and tumor-dependent…”
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The effect of early environmental manipulation on locomotor sensitivity and methamphetamine conditioned place preference reward by Hensleigh, E., Pritchard, L.M.

“…•Methamphetamine group developed a conditioned preference to the drug paired chamber.•Separated animals did not exhibit increased meth conditioned place…”
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Fetal size classified using gestational days rather than gestational weeks improves correlation with stillbirth risk: A statewide population study by Pritchard, Natasha L, Tong, Stephen, Walker, Susan P, Lindquist, Anthea C

“…Objective Many growth charts provide single centile cutoffs for each week of gestation, yet fetuses gain weight throughout the week. We aimed to assess whether…”
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Intravenous delivery of anti-RhoA small interfering RNA loaded in nanoparticles of chitosan in mice: safety and efficacy in xenografted aggressive breast cancer by Pillé, J-Y, Li, H, Blot, E, Bertrand, J-R, Pritchard, L-L, Opolon, P, Maksimenko, A, Lu, H, Vannier, J-P, Soria, J, Malvy, C, Soria, C

“…Overexpression of RhoA in cancer indicates a poor prognosis, because of increased tumor cell proliferation and invasion and tumor angiogenesis. We showed…”
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Intergenic disease-associated regions are abundant in novel transcripts by Bartonicek, N, Clark, M B, Quek, X C, Torpy, J R, Pritchard, A L, Maag, J L V, Gloss, B S, Crawford, J, Taft, R J, Hayward, N K, Montgomery, G W, Mattick, J S, Mercer, T R, Dinger, M E

“…Genotyping of large populations through genome-wide association studies (GWAS) has successfully identified many genomic variants associated with traits or…”
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G9a Inhibition Enhances Checkpoint Inhibitor Blockade Response in Melanoma by Kelly, Gregory M, Al-Ejeh, Fares, McCuaig, Robert, Casciello, Francesco, Ahmad Kamal, Nabilah, Ferguson, Blake, Pritchard, Antonia L, Ali, Sayed, Silva, Ines P, Wilmott, James S, Long, Georgina V, Scolyer, Richard A, Rao, Sudha, Hayward, Nicholas K, Gannon, Frank, Lee, Jason S

“…G9a histone methyltransferase exerts oncogenic effects in several tumor types and its inhibition promotes anticancer effects. However, the impact on checkpoint…”
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Adjusting growth standards for fetal sex improves correlation of small babies with stillbirth and adverse perinatal outcomes: A state-wide population study by Pritchard, Natasha L, Walker, Susan P, Mitchell, Alexandra R, Tong, Stephen, Lindquist, Anthea C

“…Objectives Sex impacts birthweight, with male babies heavier on average. Birthweight charts are thus sex specific, but ultrasound fetal weights are often…”
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Systematic review and meta‐analysis of genomic alterations in acral melanoma by Broit, Natasa, Johansson, Peter A., Rodgers, Chloe B., Walpole, Sebastian T., Hayward, Nicholas K., Pritchard, Antonia L.

“…Acral melanoma (AM) tumors arise on the palms, soles, fingers, toes, and nailbeds. A comprehensive systematic meta‐analysis of AM genomic aberrations has not…”
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Serious infections and mortality in association with therapies for Crohn's disease: TREAT registry by Lichtenstein, Gary R, Feagan, Brian G, Cohen, Russell D, Salzberg, Bruce A, Diamond, Robert H, Chen, Donny M, Pritchard, Michelle L, Sandborn, William J

“…Long-term safety data for infliximab and other therapies in Crohn's disease (CD) are needed. We prospectively evaluated patients for prespecified…”
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Pro-opiomelanocortin processing in the hypothalamus: impact on melanocortin signalling and obesity by Pritchard, LE, Turnbull, AV, White, A

“…Bioactive peptides derived from the prohormone, pro-opiomelanocortin (POMC), are generated in neurons of the hypothalamus and act as endogenous ligands for the…”
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Identification of the optimal growth charts for use in a preterm population: An Australian state-wide retrospective cohort study by Pritchard, Natasha L, Hiscock, Richard J, Lockie, Elizabeth, Permezel, Michael, McGauren, Monica F G, Kennedy, Amber L, Green, Brittany, Walker, Susan P, Lindquist, Anthea C

“…Preterm infants are a group at high risk of having experienced placental insufficiency. It is unclear which growth charts perform best in identifying infants…”
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Lymphoblastoid cell lines do not recapitulate physiological circulating B cell subtypes by MacKinnon, Connie, McLean, Ryan, Pritchard, Antonia L.

“…Lymphoblastoid cell lines (LCLs) are immortalised peripheral B lymphocytes, transformed via infection with Epstein Barr virus (EBV). The use of LCLs to study B…”
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Land application of sewage sludge (biosolids) in Australia: risks to the environment and food crops by Pritchard, D L, Penney, N, McLaughlin, M J, Rigby, H, Schwarz, K

“…Australia is a large exporter of agricultural products, with producers responsible for a range of quality assurance programs to ensure that food crops are free…”
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Recurrent inactivating RASA2 mutations in melanoma by Arafeh, Rand, Qutob, Nouar, Emmanuel, Rafi, Keren-Paz, Alona, Madore, Jason, Elkahloun, Abdel, Wilmott, James S, Gartner, Jared J, Di Pizio, Antonella, Winograd-Katz, Sabina, Sindiri, Sivasish, Rotkopf, Ron, Dutton-Regester, Ken, Johansson, Peter, Pritchard, Antonia L, Waddell, Nicola, Hill, Victoria K, Lin, Jimmy C, Hevroni, Yael, Rosenberg, Steven A, Khan, Javed, Ben-Dor, Shifra, Niv, Masha Y, Ulitsky, Igor, Mann, Graham J, Scolyer, Richard A, Hayward, Nicholas K, Samuels, Yardena

“…Yardena Samuels and colleagues report the analysis of 501 melanoma exomes and the identification of RASA2 as a tumor-suppressor gene mutated in 5% of…”
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Feline Model of Acute Nipah Virus Infection and Protection with a Soluble Glycoprotein-Based Subunit Vaccine by MUNGALL, Bruce A, MIDDLETON, Deborah, WANG, Lin-Fa, BOSSART, Katharine N, BRODER, Christopher C, CRAMERI, Gary, BINGHAM, John, HALPIN, Kim, RUSSELL, Gail, GREEN, Diane, MCEACHERN, Jennifer, IAN PRITCHARD, L, EATON, Bryan T

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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