Search Results - "PRIOLO, Carmen"

AKT1 and MYC induce distinctive metabolic fingerprints in human prostate cancer by Priolo, Carmen, Pyne, Saumyadipta, Rose, Joshua, Regan, Erzsébet Ravasz, Zadra, Giorgia, Photopoulos, Cornelia, Cacciatore, Stefano, Schultz, Denise, Scaglia, Natalia, McDunn, Jonathan, De Marzo, Angelo M, Loda, Massimo

“…Cancer cells may overcome growth factor dependence by deregulating oncogenic and/or tumor-suppressor pathways that affect their metabolism, or by activating…”
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A novel direct activator of AMPK inhibits prostate cancer growth by blocking lipogenesis by Zadra, Giorgia, Photopoulos, Cornelia, Tyekucheva, Svitlana, Heidari, Pedram, Weng, Qing Ping, Fedele, Giuseppe, Liu, Hong, Scaglia, Natalia, Priolo, Carmen, Sicinska, Ewa, Mahmood, Umar, Signoretti, Sabina, Birnberg, Neal, Loda, Massimo

“…5′AMP‐activated kinase (AMPK) constitutes a hub for cellular metabolic and growth control, thus representing an ideal therapeutic target for prostate cancers…”
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Impairment of gamma-glutamyl transferase 1 activity in the metabolic pathogenesis of chromophobe renal cell carcinoma by Priolo, Carmen, Khabibullin, Damir, Reznik, Ed, Filippakis, Harilaos, Ogórek, Barbara, Kavanagh, Taylor R., Nijmeh, Julie, Herbert, Zachary T., Asara, John M., Kwiatkowski, David J., Wu, Chin-Lee, Henske, Elizabeth P.

“…Chromophobe renal cell carcinoma (ChRCC) accounts for 5% of all sporadic renal cancers and can also occur in genetic syndromes including Birt–Hogg–Dube (BHD)…”
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New Strategies in Prostate Cancer: Targeting Lipogenic Pathways and the Energy Sensor AMPK by ZADRA, Giorgia, PRIOLO, Carmen, PATNAIK, Akash, LODA, Massimo

“…Although the role of metabolic syndrome (MS) and a high fat diet in prostate cancer (PCa) risk is still a matter of intense debate, it is becoming increasingly…”
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Fatty Acid Synthase: A Metabolic Enzyme and Candidate Oncogene in Prostate Cancer by Migita, Toshiro, Ruiz, Stacey, Fornari, Alessandro, Fiorentino, Michelangelo, Priolo, Carmen, Zadra, Giorgia, Inazuka, Fumika, Grisanzio, Chiara, Palescandolo, Emanuele, Shin, Eyoung, Fiore, Christopher, Xie, Wanling, Kung, Andrew L., Febbo, Phillip G., Subramanian, Aravind, Mucci, Lorelei, Ma, Jing, Signoretti, Sabina, Stampfer, Meir, Hahn, William C., Finn, Stephen, Loda, Massimo

“…Background Overexpression of the fatty acid synthase (FASN) gene has been implicated in prostate carcinogenesis. We sought to directly assess the oncogenic…”
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Plasma metabolomics and clinical predictors of survival differences in COPD patients by Pinto-Plata, Victor, Casanova, Ciro, Divo, Miguel, Tesfaigzi, Yohannes, Calhoun, Vince, Sui, Jing, Polverino, Francesca, Priolo, Carmen, Petersen, Hans, de Torres, Juan Pablo, Marin, Jose Maria, Owen, Caroline A, Baz, Rebeca, Cordova, Elizabeth, Celli, Bartolome

“…Plasma metabolomics profile (PMP) in COPD has been associated with clinical characteristics, but PMP's relationship to survival has not been reported. We…”
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Estradiol and mTORC2 cooperate to enhance prostaglandin biosynthesis and tumorigenesis in TSC2-deficient LAM cells by Li, Chenggang, Lee, Po-Shun, Sun, Yang, Gu, Xiaoxiao, Zhang, Erik, Guo, Yanan, Wu, Chin-Lee, Auricchio, Neil, Priolo, Carmen, Li, Jing, Csibi, Alfredo, Parkhitko, Andrey, Morrison, Tasha, Planaguma, Anna, Kazani, Shamsah, Israel, Elliot, Xu, Kai-Feng, Henske, Elizabeth Petri, Blenis, John, Levy, Bruce D, Kwiatkowski, David, Yu, Jane J

“…Lymphangioleiomyomatosis (LAM) is a progressive neoplastic disorder that leads to lung destruction and respiratory failure primarily in women. LAM is typically…”
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Glycogen synthase kinase 3-β inhibition induces lymphangiogenesis through β-catenin-dependent and mTOR-independent pathways by Stump, Benjamin, Shrestha, Shikshya, Lamattina, Anthony M, Louis, Pierce H, Cho, Woohyun, Perrella, Mark A, Ai, Xingbin, Rosas, Ivan O, Wagner, Florence F, Priolo, Carmen, Astin, Jonathan, El-Chemaly, Souheil

“…Lymphatic vessels play an important role in health and in disease. In this study, we evaluated the effects of GSK3-β inhibition on lung lymphatic endothelial…”
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Tuberous sclerosis complex 2 loss increases lysophosphatidylcholine synthesis in lymphangioleiomyomatosis by Priolo, Carmen, Ricoult, Stéphane J H, Khabibullin, Damir, Filippakis, Harilaos, Yu, Jane, Manning, Brendan D, Clish, Clary, Henske, Elizabeth P

“…Lymphangioleiomyomatosis (LAM) is a destructive lung disease affecting women. LAM is caused by mutations in the tuberous sclerosis complex (TSC) genes. The TSC…”
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MicroRNA-21 is induced by rapamycin in a model of tuberous sclerosis (TSC) and lymphangioleiomyomatosis (LAM) by Trindade, Anil J, Medvetz, Douglas A, Neuman, Nicole A, Myachina, Faina, Yu, Jane, Priolo, Carmen, Henske, Elizabeth P

“…Lymphangioleiomyomatosis (LAM), a multisystem disease of women, is manifest by the proliferation of smooth muscle-like cells in the lung resulting in cystic…”
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The isopeptidase USP2a protects human prostate cancer from apoptosis by PRIOLO, Carmen, DAN TANG, FEBBO, Phillip, LODA, Massimo, BRAHAMANDAN, Mohan, BENASSI, Barbara, SICINSKA, Ewa, OGINO, Shuji, FARSETTI, Antonella, PORRELLO, Alessandro, FINN, Stephen, ZIMMERMANN, Johann

“…Deubiquitinating enzymes can prevent the destruction of protein substrates prior to proteasomal degradation. The ubiquitin-specific protease 2a (USP2a)…”
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Establishment and Genomic Characterization of Mouse Xenografts of Human Primary Prostate Tumors by Priolo, Carmen, Agostini, Michelle, Vena, Natalie, Ligon, Azra H, Fiorentino, Michelangelo, Shin, Eyoung, Farsetti, Antonella, Pontecorvi, Alfredo, Sicinska, Ewa, Loda, Massimo

“…Serum prostate-specific antigen screening has led to earlier detection and surgical treatment of prostate cancer, favoring an increasing incidence-to-mortality…”
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FOXA1 Is a Potential Oncogene in Anaplastic Thyroid Carcinoma by NUCERA, Carmelo, EECKHOUTE, Jerome, PONTECORVI, Alfredo, NOSE, Vania, LODA, Massimo, BROWN, Myles, FINN, Stephen, CARROLL, Jason S, LIGON, Azra H, PRIOLO, Carmen, FADDA, Guido, TONER, Mary, SHEILS, Orla, ATTARD, Marco

“…Purpose: FOXA1 is a mammalian endodermal transcription factor belonging to the human forkhead box gene family that plays a role in certain tumor types. Here,…”
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A novel direct activator of AMPK inhibits prostate cancer growth by blocking lipogenesis by Zadra, Giorgia, Photopoulos, Cornelia, Tyekucheva, Svitlana, Heidari, Pedram, Weng, Qing Ping, Fedele, Giuseppe, Liu, Hong, Scaglia, Natalia, Priolo, Carmen, Sicinska, Ewa, Mahmood, Umar, Signoretti, Sabina, Birnberg, Neal, Loda, Massimo

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Role of BRAFV600E in the first preclinical model of multifocal infiltrating myopericytoma development and microenvironment by Sadow, Peter M, Priolo, Carmen, Nanni, Simona, Karreth, Florian A, Duquette, Mark, Martinelli, Roberta, Husain, Amjad, Clohessy, John, Kutzner, Heinz, Mentzel, Thomas, Carman, Christopher V, Farsetti, Antonella, Henske, Elizabeth Petri, Palescandolo, Emanuele, Macconaill, Laura E, Chung, Seum, Fadda, Guido, Lombardi, Celestino Pio, De Angelis, Antonina M, Durante, Oreste, Parker, John A, Pontecorvi, Alfredo, Dvorak, Harold F, Fletcher, Christopher, Pandolfi, Pier Paolo, Lawler, Jack, Nucera, Carmelo

“…Myopericytoma (MPC) is a rare tumor with perivascular proliferation of pluripotent stem-cell-like pericytes. Although indolent, MPC may be locally aggressive…”
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Epithelial-Restricted Gene Profile of Primary Cultures from Human Prostate Tumors: A Molecular Approach to Predict Clinical Behavior of Prostate Cancer by Nanni, Simona, Priolo, Carmen, Grasselli, Annalisa, D'Eletto, Manuela, Merola, Roberta, Moretti, Fabiola, Gallucci, Michele, De Carli, Piero, Sentinelli, Steno, Cianciulli, Anna Maria, Mottolese, Marcella, Carlini, Paolo, Arcelli, Diego, Helmer-Citterich, Mauro, Gaetano, Carlo, Loda, Massimo, Pontecorvi, Alfredo, Bacchetti, Silvia, Sacchi, Ada, Farsetti, Antonella

“…The histopathologic and molecular heterogeneity of prostate cancer and the limited availability of human tumor tissue make unraveling the mechanisms of…”
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B-RafV600E and thrombospondin-1 promote thyroid cancer progression by Nucera, Carmelo, Porrello, Alessandro, Antonello, Zeus Andrea, Mekel, Michal, Nehs, Matthew A., Giordano, Thomas J., Gerald, Damien, Benjamin, Laura E., Priolo, Carmen, Puxeddu, Efisio, Finn, Stephen, Jarzab, Barbara, Hodin, Richard A., Pontecorvi, Alfredo, Nose, Vânia, Lawler, Jack, Parangi, Sareh

“…Although B-Raf V600E is the most common somatic mutation in papillary thyroid carcinoma (PTC), how it induces tumor aggressiveness is not fully understood…”
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Immunometabolic Endothelial Phenotypes: Integrating Inflammation and Glucose Metabolism by Xiao, Wusheng, Oldham, William M., Priolo, Carmen, Pandey, Arvind K., Loscalzo, Joseph

“…[Figure: see text]…”
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52 Ferroptosis Suppressor Protein 1 is a Potent and Targetable Inhibitor of Ferroptosis in Chromophobe Renal Cell by Salem, Samer, Mahmoud, Nadine, Chami, Joelle, Alchoueiry, Michel, Daou, Melissa, Mansour, Hadi, Khabibullin, Damir, Priolo, Carmen, Henske, Elizabeth

“…Abstract Background There are currently no proven therapies for metastatic or unresectable Chromophobe renal cell carcinoma (ChRCC). Ferroptosis is an…”
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Therapeutic targeting of cellular metabolism in cells with hyperactive mTORC1: a paradigm shift by Medvetz, Doug, Priolo, Carmen, Henske, Elizabeth P

“…mTORC1 is an established master regulator of cellular metabolic homeostasis, via multiple mechanisms that include altered glucose and glutamine metabolism, and…”
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