Search Results - "PRINCE, John T"

Mitochondrial fission mediates ceramide-induced metabolic disruption in skeletal muscle by Smith, Melissa E, Tippetts, Trevor S, Brassfield, Eric S, Tucker, Braden J, Ockey, Adelaide, Swensen, Adam C, Anthonymuthu, Tamil S, Washburn, Trevor D, Kane, Daniel A, Prince, John T, Bikman, Benjamin T

“…Ceramide is a sphingolipid that serves as an important second messenger in an increasing number of stress-induced pathways. Ceramide has long been known to…”
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Structures of the Gβ-CCT and PhLP1–Gβ-CCT complexes reveal a mechanism for G-protein β-subunit folding and Gβγ dimer assembly by Plimpton, Rebecca L., Cuéllar, Jorge, Lai, Chun Wan J., Aoba, Takuma, Makaju, Aman, Franklin, Sarah, Mathis, Andrew D., Prince, John T., Carrascosa, José L., Valpuesta, José M., Willardson, Barry M.

“…G-protein signaling depends on the ability of the individual subunits of the G-protein heterotrimer to assemble into a functional complex. Formation of the…”
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A comprehensive protein-protein interactome for yeast PAS kinase 1 reveals direct inhibition of respiration through the phosphorylation of Cbf1 by DeMille, Desiree, Bikman, Benjamin T, Mathis, Andrew D, Prince, John T, Mackay, Jordan T, Sowa, Steven W, Hall, Tacie D, Grose, Julianne H

“…Per-Arnt-Sim (PAS) kinase is a sensory protein kinase required for glucose homeostasis in yeast, mice, and humans, yet little is known about the molecular…”
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Yersinia pseudotuberculosis BarA-UvrY Two-Component Regulatory System Represses Biofilms via CsrB by Schachterle, Jeffrey K, Stewart, Ryan M, Schachterle, M Brett, Calder, Joshua T, Kang, Huan, Prince, John T, Erickson, David L

“…The formation of biofilms by ( ) and requires the genes, which direct production of a polysaccharide extracellular matrix (Hms-ECM). Despite possessing…”
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Sequence and Structural Characterization of Great Salt Lake Bacteriophage CW02, a Member of the T7-Like Supergroup by SHEN, Peter S, DOMEK, Matthew J, BELNAP, David M, SANZ-GARCIA, Eduardo, MAKAJU, Aman, TAYLOR, Ryan M, HOGGAN, Ryan, CULUMBER, Michele D, OBERG, Craig J, BREAKWELL, Donald P, PRINCE, John T

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The need for a public proteomics repository by Marcotte, Edward M, Prince, John T, Carlson, Mark W, Wang, Rong, Lu, Peng

“…Large-scale protein expression measurements promise to open exciting areas of research, ranging from systematic investigations of post-transcriptional…”
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mspire: mass spectrometry proteomics in Ruby by Prince, John T., Marcotte, Edward M.

“…Mass spectrometry-based proteomics stands to gain from additional analysis of its data, but its large, complex datasets make demands on speed and memory usage…”
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Chromatographic Alignment of ESI-LC-MS Proteomics Data Sets by Ordered Bijective Interpolated Warping by Prince, John T, Marcotte, Edward M

“…Mass spectrometry proteomics typically relies upon analyzing outcomes of single analyses; however, comparing raw data across multiple experiments should…”
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Novel algorithms and the benefits of comparative validation by Smith, Robert, Ventura, Dan, Prince, John T

“…Contact:  2robsmith@gmail.com…”
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Proteomics, lipidomics, metabolomics: a mass spectrometry tutorial from a computer scientist's point of view by Smith, Rob, Mathis, Andrew D, Ventura, Dan, Prince, John T

“…For decades, mass spectrometry data has been analyzed to investigate a wide array of research interests, including disease diagnostics, biological and chemical…”
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Probabilistic Generation of Mass Spectrometry Molecular Abundance Variance for Case and Control Replicates by Prince, John T, Smith, Rob

“…Shotgun differential mass spectrometry, the untargeted discovery of statistically significant differences between two or more samples, is a popular application…”
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LC-MS alignment in theory and practice: a comprehensive algorithmic review by Smith, Rob, Ventura, Dan, Prince, John T

“…Liquid chromatography-mass spectrometry is widely used for comparative replicate sample analysis in proteomics, lipidomics and metabolomics. Before statistical…”
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JAMSS: proteomics mass spectrometry simulation in Java by Smith, Rob, Prince, John T

“…Countless proteomics data processing algorithms have been proposed, yet few have been critically evaluated due to lack of labeled data (data with known…”
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Metabolic-Stress-Induced Rearrangement of the 14-3-3ζ Interactome Promotes Autophagy via a ULK1- and AMPK-Regulated 14-3-3ζ Interaction with Phosphorylated Atg9 by Weerasekara, Vajira K., Panek, David J., Broadbent, David G., Mortenson, Jeffrey B., Mathis, Andrew D., Logan, Gideon N., Prince, John T., Thomson, David M., Thompson, J. Will, Andersen, Joshua L.

“…14-3-3ζ promotes cell survival via dynamic interactions with a vast network of binding partners, many of which are involved in stress regulation. We show here…”
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AICAR inhibits ceramide biosynthesis in skeletal muscle by Erickson, Katherine A, Smith, Melissa E, Anthonymuthu, Tamil S, Evanson, Michael J, Brassfield, Eric S, Hodson, Aimee E, Bressler, M Andrew, Tucker, Braden J, Thatcher, Mikayla O, Prince, John T, Hancock, Chad R, Bikman, Benjamin T

“…The worldwide prevalence of obesity has lead to increased efforts to find therapies to treat obesity-related pathologies. Ceramide is a well-established…”
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Construction, Cloning, and Expression of Synthetic Genes Encoding Spider Dragline Silk by Prince, John T, McGrath, Kevin P, DiGirolamo, Carla M, Kaplan, David L

“…Synthetic genes encoding recombinant spider silk proteins have been constructed, cloned, and expressed. Protein sequences were derived from Nephila clavipes…”
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A coherent mathematical characterization of isotope trace extraction, isotopic envelope extraction, and LC-MS correspondence by Smith, Rob, Prince, John T, Ventura, Dan

“…Liquid chromatography-mass spectrometry is a popular technique for high-throughput protein, lipid, and metabolite comparative analysis. Such statistical…”
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Current controlled vocabularies are insufficient to uniquely map molecular entities to mass spectrometry signal by Smith, Rob, Taylor, Ryan M, Prince, John T

“…The comparison of analyte mass spectrometry precursor (MS1) signal is central to many proteomic (and other -omic) workflows. Standard vocabularies for mass…”
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Metriculator: quality assessment for mass spectrometry-based proteomics by Taylor, Ryan M, Dance, Jamison, Taylor, Russ J, Prince, John T

“…Quality control in mass spectrometry-based proteomics remains subjective, labor-intensive and inconsistent between laboratories. We introduce Metriculator, a…”
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Massifquant: open-source Kalman filter-based XC-MS isotope trace feature detection by Conley, Christopher J, Smith, Rob, Torgrip, Ralf J O, Taylor, Ryan M, Tautenhahn, Ralf, Prince, John T

“…Isotope trace (IT) detection is a fundamental step for liquid or gas chromatography mass spectrometry (XC-MS) data analysis that faces a multitude of technical…”
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