Search Results - "PREUSSER, Matthias"
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EANO guidelines on the diagnosis and treatment of diffuse gliomas of adulthood
Published in Nature reviews. Clinical oncology (01-03-2021)“…In response to major changes in diagnostic algorithms and the publication of mature results from various large clinical trials, the European Association of…”
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European Association for Neuro-Oncology (EANO) guideline on the diagnosis and treatment of adult astrocytic and oligodendroglial gliomas
Published in The lancet oncology (01-06-2017)“…Summary The European Association for Neuro-Oncology guideline provides recommendations for the clinical care of adult patients with astrocytic and…”
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3
The DNA methylation landscape of glioblastoma disease progression shows extensive heterogeneity in time and space
Published in Nature medicine (01-10-2018)“…Glioblastoma is characterized by widespread genetic and transcriptional heterogeneity, yet little is known about the role of the epigenome in glioblastoma…”
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EANO guideline on the diagnosis and management of meningiomas
Published in Neuro-oncology (Charlottesville, Va.) (02-11-2021)“…Abstract Meningiomas are the most common intracranial tumors. Yet, only few controlled clinical trials have been conducted to guide clinical decision making,…”
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Incidence, risk factors, and outcomes of venous and arterial thromboembolism in immune checkpoint inhibitor therapy
Published in Blood (25-03-2021)“…The risk of venous thromboembolism (VTE) and arterial thromboembolism (ATE) associated with immune checkpoint inhibitors is currently unclear. Our aim was to…”
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Prospects of immune checkpoint modulators in the treatment of glioblastoma
Published in Nature reviews. Neurology (01-09-2015)“…Key Points The prognosis for glioblastoma patients is poor, with median overall survival of approximately 15–17 months Immunotherapy has clinical benefits in…”
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Diagnosis and treatment of primary CNS lymphoma in immunocompetent patients: guidelines from the European Association for Neuro-Oncology
Published in The lancet oncology (01-07-2015)“…Summary The management of primary CNS lymphoma is one of the most controversial topics in neuro-oncology because of the complexity of the disease and the very…”
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Does neoadjuvant anti-PD1 therapy improve glioblastoma outcome?
Published in Nature reviews. Neurology (01-06-2019)“…Studies in melanoma and lung cancer indicate that shifting use of immune checkpoint inhibition from palliative stages to the neoadjuvant setting improves…”
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EANO guidelines for the diagnosis and treatment of meningiomas
Published in The lancet oncology (01-09-2016)“…Summary Although meningiomas are the most common intracranial tumours, the level of evidence to provide recommendations for the diagnosis and treatment of…”
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Glioblastoma in adults: a Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) consensus review on current management and future directions
Published in Neuro-oncology (Charlottesville, Va.) (17-08-2020)“…Abstract Glioblastomas are the most common form of malignant primary brain tumor and an important cause of morbidity and mortality. In recent years there have…”
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A step towards clinical blood biomarkers of glioblastoma
Published in Nature reviews. Neurology (01-12-2014)“…Glioblastoma is the most common primary brain tumour in adults, but—unlike many other cancers—no blood-based biomarkers are available for differential…”
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DNA methylation-based classification and grading system for meningioma: a multicentre, retrospective analysis
Published in The lancet oncology (01-05-2017)“…Summary Background The WHO classification of brain tumours describes 15 subtypes of meningioma. Nine of these subtypes are allotted to WHO grade I, and three…”
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Current concepts and management of glioblastoma
Published in Annals of neurology (01-07-2011)“…Glioblastoma is the most common malignant primary brain tumor in adults. Its often rapid clinical course, with many medical and psychosocial challenges,…”
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14
Podoplanin expression in primary brain tumors induces platelet aggregation and increases risk of venous thromboembolism
Published in Blood (30-03-2017)“…Venous thromboembolism (VTE) is common in patients with brain tumors, and underlying mechanisms are unclear. We hypothesized that podoplanin, a sialomucin-like…”
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CDKN2A/B homozygous deletion is associated with early recurrence in meningiomas
Published in Acta neuropathologica (01-09-2020)Get full text
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Integrated Molecular-Morphologic Meningioma Classification: A Multicenter Retrospective Analysis, Retrospectively and Prospectively Validated
Published in Journal of clinical oncology (01-12-2021)“…Meningiomas are the most frequent primary intracranial tumors. Patient outcome varies widely from benign to highly aggressive, ultimately fatal courses…”
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Genomic characterization of human brain metastases identifies drivers of metastatic lung adenocarcinoma
Published in Nature genetics (01-04-2020)“…Brain metastases from lung adenocarcinoma (BM-LUAD) frequently cause patient mortality. To identify genomic alterations that promote brain metastases, we…”
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Diagnosis and treatment of brain metastases from solid tumors: guidelines from the European Association of Neuro-Oncology (EANO)
Published in Neuro-oncology (Charlottesville, Va.) (01-02-2017)“…The management of patients with brain metastases has become a major issue due to the increasing frequency and complexity of the diagnostic and therapeutic…”
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Assessing Tumor-Infiltrating Lymphocytes in Solid Tumors: A Practical Review for Pathologists and Proposal for a Standardized Method from the International Immuno-Oncology Biomarkers Working Group: Part 2: TILs in Melanoma, Gastrointestinal Tract Carcinomas, Non–Small Cell Lung Carcinoma and Mesothelioma, Endometrial and Ovarian Carcinomas, Squamous Cell Carcinoma of the Head and Neck, Genitourinary Carcinomas, and Primary Brain Tumors
Published in Advances in anatomic pathology (01-11-2017)“…Assessment of the immune response to tumors is growing in importance as the prognostic implications of this response are increasingly recognized, and as…”
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Assessing Tumor-infiltrating Lymphocytes in Solid Tumors: A Practical Review for Pathologists and Proposal for a Standardized Method From the International Immunooncology Biomarkers Working Group: Part 1: Assessing the Host Immune Response, TILs in Invasive Breast Carcinoma and Ductal Carcinoma In Situ, Metastatic Tumor Deposits and Areas for Further Research
Published in Advances in anatomic pathology (01-09-2017)“…Assessment of tumor-infiltrating lymphocytes (TILs) in histopathologic specimens can provide important prognostic information in diverse solid tumor types, and…”
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