Search Results - "PRASADARAO, Nemani V"

Outer membrane protein A and OprF: versatile roles in Gram‐negative bacterial infections by Krishnan, Subramanian, Prasadarao, Nemani V.

“…Outer membrane protein A (OmpA) is an abundant protein of Escherichia coli and other enterobacteria and has a multitude of functions. Although the structural…”
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Mechanisms of Candida albicans trafficking to the brain by Liu, Yaoping, Mittal, Rahul, Solis, Norma V, Prasadarao, Nemani V, Filler, Scott G

“…During hematogenously disseminated disease, Candida albicans infects most organs, including the brain. We discovered that a C. albicans vps51Δ/Δ mutant had…”
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SR-Like RNA-Binding Protein Slr1 Affects Candida albicans Filamentation and Virulence by Ariyachet, Chaiyaboot, Solis, Norma V, Liu, Yaoping, Prasadarao, Nemani V, Filler, Scott G, McBride, Anne E

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Inhibition of Inducible Nitric Oxide Controls Pathogen Load and Brain Damage by Enhancing Phagocytosis of Escherichia coli K1 in Neonatal Meningitis by Mittal, Rahul, Gonzalez-Gomez, Ignacio, Goth, Kerstin A, Prasadarao, Nemani V

“…Escherichia coli K1 is a leading cause of neonatal meningitis in humans. In this study, we sought to determine the pathophysiologic relevance of inducible…”
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Role of Neutrophils and Macrophages in the Pathogenesis of Necrotizing Enterocolitis Caused by Cronobacter sakazakii by Emami, Claudia N., M.D., M.P.H, Mittal, Rahul, Ph.D, Wang, Larry, M.D, Ford, Henri R., M.D., M.H.A, Prasadarao, Nemani V., Ph.D

“…Background Cronobacter sakazakii (CS) is a highly virulent gram-negative opportunistic pathogen that has been implicated in clinical outbreaks of necrotizing…”
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Angiotensin II Receptor Type 1—A Novel Target for Preventing Neonatal Meningitis in Mice by Escherichia coli K1 by Krishnan, Subramanian, Shanmuganathan, Muthusamy V., Behenna, Douglas, Stoltz, Brian M., Prasadarao, Nemani V.

“…The increasing incidence of Escherichia coli K1 meningitis due to escalating antibiotic resistance warrants alternate treatment options to prevent this deadly…”
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Enterobacter sakazakii Enhances Epithelial Cell Injury by Inducing Apoptosis in a Rat Model of Necrotizing Enterocolitis by Hunter, Catherine J., Singamsetty, Vijay K., Chokshi, Nikunj K., Boyle, Patricia, Camerini, Victoria, Grishin, Anatoly V., Upperman, Jeffrey S., Ford, Henri R., Prasadarao, Nemani V.

“…Necrotizing enterocolitis (NEC) is an inflammatory intestinal disorder that affects 2%–5% of all premature infants. Enterobacter sakazakii, a common…”
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Lactobacillus bulgaricus Prevents Intestinal Epithelial Cell Injury Caused by Enterobacter sakazakii-Induced Nitric Oxide both In Vitro and in the Newborn Rat Model of Necrotizing Enterocolitis by HUNTER, Catherine J, WILLIAMS, Monica, PETROSYAN, Mikael, GUNER, Yigit, MITTAL, Rahul, MOCK, Dennis, UPPERMAN, Jeffrey S, FORD, Henri R, PRASADARAO, Nemani V

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Identification of Escherichia coli Outer Membrane Protein A Receptor on Human Brain Microvascular Endothelial Cells by PRASADARAO, Nemani V

“…AUTHOR'S CORRECTION ( vol. 70 , p. 6513 ) Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike…”
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Am80‐GCSF synergizes myeloid expansion and differentiation to generate functional neutrophils that reduce neutropenia‐associated infection and mortality by Li, Lin, Qi, Xiaotian, Sun, Weili, Abdel‐Azim, Hisham, Lou, Siyue, Zhu, Hong, Prasadarao, Nemani V, Zhou, Alice, Shimada, Hiroyuki, Shudo, Koichi, Kim, Yong‐Mi, Khazal, Sajad, He, Qiaojun, Warburton, David, Wu, Lingtao

“…Neutrophils generated by granulocyte colony‐stimulating factor (GCSF) are functionally immature and, consequently, cannot effectively reduce infection and…”
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Human Isolates of Cronobacter sakazakii Bind Efficiently to Intestinal Epithelial Cells In Vitro to Induce Monolayer Permeability and Apoptosis by Liu, Quin, M.D, Mittal, Rahul, Ph.D, Emami, Claudia N., M.D., M.P.H, Iversen, Carol, Ph.D, Ford, Henri R., M.D., M.H.A, Prasadarao, Nemani V., Ph.D

“…Background Cronobacter sakazakii (CS) is an emerging opportunistic pathogen that causes life-threatening infections in infants. This pathogen has been…”
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Fcγ receptor I alpha chain (CD64) expression in macrophages is critical for the onset of meningitis by Escherichia coli K1 by Mittal, Rahul, Sukumaran, Sunil K, Selvaraj, Suresh K, Wooster, David G, Babu, M Madan, Schreiber, Alan D, Verbeek, J Sjef, Prasadarao, Nemani V

“…Neonatal meningitis due to Escherichia coli K1 is a serious illness with unchanged morbidity and mortality rates for the last few decades. The lack of a…”
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N-cadherin Mediates Endocytosis of Candida albicans by Endothelial Cells by Phan, Quynh T., Fratti, Rutillio A., Prasadarao, Nemani V., Edwards, John E., Filler, Scott G.

“…Candida albicans is the most common cause of fungal bloodstream infections. To invade the deep tissues, blood-borne organisms must cross the endothelial cell…”
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CTX-M beta-lactamase production and virulence of Escherichia coli K1 by Dubois, Damien, Prasadarao, Nemani V, Mittal, Rahul, Bret, Laurent, Roujou-Gris, Marie, Bonnet, Richard

“…We report a patient with neonatal meningitis caused by a CTX-M-1-producing Escherichia coli K1 strain. The influence of CTX-M production on virulence was…”
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Entry and Intracellular Replication of Escherichia coli K1 in Macrophages Require Expression of Outer Membrane Protein A by SUKUMARAN, Sunil K, SHIMADA, Hiroyuki, PRASADARAO, Nemani V

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P-glycoprotein induction by breast milk attenuates intestinal inflammation in experimental necrotizing enterocolitis by Guner, Yigit S, Franklin, Ashanti L, Chokshi, Nikunj K, Castle, Shannon L, Pontarelli, Elizabeth, Wang, Jin, Wang, Larry, Prasadarao, Nemani V, Upperman, Jeffrey S, Grishin, Anatoly V, Ford, Henri R

“…P-glycoprotein (Pgp), a product of the multi-drug resistance gene MDR1a, is a broad specificity efflux ATP cassette transmembrane transporter that is…”
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Escherichia coli K1 inhibits proinflammatory cytokine induction in monocytes by preventing NF-κB activation by Selvaraj, Suresh K., Prasadarao, Nemani V.

“…Phagocytes are well‐known effectors of the innate immune system to produce proinflammatory cytokines and chemokines such as tumor necrosis factor α (TNF‐α),…”
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Escherichia coli K1 Invasion Increases Human Brain Microvascular Endothelial Cell Monolayer Permeability by Disassembling Vascular-Endothelial Cadherins at Tight Junctions by Sukumaran, Sunil K., Prasadarao, Nemani V.

“…We investigated the permeability changes that occur in the human brain microvascular endothelial cell (HBMEC) monolayer, an in vitro model of the blood-brain…”
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gp96 expression in neutrophils is critical for the onset of Escherichia coli K1 (RS218) meningitis by Mittal, Rahul, Prasadarao, Nemani V.

“…Despite the fundamental function of neutrophils (polymorphonuclear leukocytes (PMNs)) in innate immunity, their role in Escherichia coli K1 (EC-K1) -induced…”
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Tuberculous meningitis: a roadmap for advancing basic and translational research by Jain, Sanjay K., Tobin, David M., Tucker, Elizabeth W., Venketaraman, Vishwanath, Ordonez, Alvaro A., Jayashankar, Lakshmi, Siddiqi, Omar K., Hammoud, Dima A., Prasadarao, Nemani V., Sandor, Matyas, Hafner, Richard, Fabry, Zsuzsanna

“…Tuberculous meningitis is a serious, life-threatening disease affecting vulnerable populations, including HIV-infected individuals and young children. The US…”
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