Search Results - "PRANDINI, Silvia"
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Effect of longacting somatostatin analogue on kidney and cyst growth in autosomal dominant polycystic kidney disease (ALADIN): a randomised, placebo-controlled, multicentre trial
Published in The Lancet (British edition) (02-11-2013)“…Summary Background Autosomal dominant polycystic kidney disease slowly progresses to end-stage renal disease and has no effective therapy. A pilot study…”
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2
Octreotide-LAR in later-stage autosomal dominant polycystic kidney disease (ALADIN 2): A randomized, double-blind, placebo-controlled, multicenter trial
Published in PLoS medicine (05-04-2019)“…Autosomal dominant polycystic kidney disease (ADPKD) is the most frequent genetically determined renal disease. In affected patients, renal function may…”
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3
Sirolimus Therapy to Halt the Progression of ADPKD
Published in Journal of the American Society of Nephrology (01-06-2010)“…Activation of mammalian target of rapamycin (mTOR) pathways may contribute to uncontrolled cell proliferation and secondary cyst growth in patients with…”
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4
Preventing microalbuminuria with benazepril, valsartan, and benazepril–valsartan combination therapy in diabetic patients with high-normal albuminuria: A prospective, randomized, open-label, blinded endpoint (PROBE) study
Published in PLoS medicine (01-07-2021)“…Background Angiotensin converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) prevent microalbuminuria in normoalbuminuric type 2 diabetic…”
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5
Measuring and estimating GFR and treatment effect in ADPKD patients: results and implications of a longitudinal cohort study
Published in PloS one (28-02-2012)“…Trials failed to demonstrate protective effects of investigational treatments on glomerular filtration rate (GFR) reduction in Autosomal Dominant Polycystic…”
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A GWAS in the pandemic epicenter highlights the severe COVID-19 risk locus introgressed by Neanderthals
Published in iScience (20-10-2023)“…Large GWAS indicated that genetic factors influence the response to SARS-CoV-2. However, sex, age, concomitant diseases, differences in ancestry, and uneven…”
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7
Paricalcitol for secondary hyperparathyroidism in renal transplantation
Published in Journal of the American Society of Nephrology (01-05-2015)“…Secondary hyperparathyroidism contributes to post-transplant CKD mineral and bone disorder. Paricalcitol, a selective vitamin D receptor activator, decreased…”
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8
Preventing microalbuminuria with benazepril, valsartan, and benazepril-valsartan combination therapy in diabetic patients with high-normal albuminuria: A prospective, randomized, open-label, blinded endpoint
Published in PLoS medicine (14-07-2021)“…Background Angiotensin converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) prevent microalbuminuria in normoalbuminuric type 2 diabetic…”
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9
Effect of Sirolimus on Disease Progression in Patients with Autosomal Dominant Polycystic Kidney Disease and CKD Stages 3b-4
Published in Clinical journal of the American Society of Nephrology (06-05-2016)“…The effect of mammalian target of rapamycin (mTOR) inhibitors has never been tested in patients with autosomal dominant polycystic kidney disease (ADPKD) and…”
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10
Octreotide-LAR in later-stage autosomal dominant polycystic kidney disease
Published in PLoS medicine (05-04-2019)“…Background Autosomal dominant polycystic kidney disease (ADPKD) is the most frequent genetically determined renal disease. In affected patients, renal function…”
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Journal Article -
11
Moderate salt restriction with or without paricalcitol in type 2 diabetes and losartan-resistant macroalbuminuria (PROCEED): a randomised, double-blind, placebo-controlled, crossover trial
Published in The lancet. Diabetes & endocrinology (01-01-2018)“…Macroalbuminuria predicts renal and cardiovascular events in patients with type 2 diabetes. We aimed to assess the albuminuria-lowering effects of salt…”
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