Search Results - "PRADHAN, Rajendra"

Binary Mixtures of 2-Ethyl-1-hexanol and 1, 2-Disubstituted Ethanes: Thermophysical, Ultraacoustic and Computational Studies by Pradhan, Rajendra, Roy, Dhruba Jyoti, Das, Soumik, Pradhan, Sudarshan, Chettri, Anmol, Sinha, Biswajit

“…Densities ( ρ ) and viscosities ( η ) of the binary mixtures of 2-ethyl-1-hexanol (2-EH) with ethylenediamine, 1,2-dichloroethane (DCE) and monoethanolamine…”
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Thermophysical properties of binary blends of cyclohexane with some esters by Pradhan, Rajendra, Sinha, Biswajit

“…From the densities (?) and viscosities (?) measured for three binary blends consisting of methyl acetate (MA), ethyl acetate (EA) and methyl salicylate (MS)…”
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Exposure-Response (Safety) Analysis to Identify Linifanib Dose for a Phase III Study in Patients With Hepatocellular Carcinoma by Chiu, Yi-Lin, PhD, Carlson, Dawn M., MD, Pradhan, Rajendra S., PhD, Ricker, Justin L., MD, PhD

“…Abstract Background Hepatocellular carcinoma (HCC) is the third most common cause of cancer-related deaths and the fifth most common cancer globally…”
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Phase I/II Study of Pemetrexed With or Without ABT-751 in Advanced or Metastatic Non–Small-Cell Lung Cancer by RUDIN, Charles M, MAUER, Ann, JANE QIAN, PRADHAN, Rajendra, DOWELL, Barry, KRIVOSHIK, Andrew, GORDON, Gary, SMAKAL, Martin, JUERGENS, Rosalyn, SPELDA, Stanislav, WERTHEIM, Michael, COATES, Andrew, MCKEEGAN, Evelyn, ANSELL, Peter, XIANGDONG ZHOU

“…ABT-751 is an antimitotic and vascular disrupting agent with potent preclinical anticancer activity. We conducted a phase I and randomized double-blind phase…”
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Phase I and Biomarker Study of ABT-869, a Multiple Receptor Tyrosine Kinase Inhibitor, in Patients With Refractory Solid Malignancies by WONG, Chiung-Ing, KOH, Tong-San, LIM, Robert, SUKRI, Norita, LIM, Siew-Eng, ONG, Ai-Bee, STEINBERG, Joyce, GUPTA, Neeraj, PRADHAN, Rajendra, HUMERICKHOUSE, Rod, GOH, Boon-Cher, SOO, Ross, HARTONO, Septian, THNG, Choon-Hua, MCKEEGAN, Evelyn, YONG, Wei-Peng, CHEN, Chien-Shing, LEE, Soo-Chin, WONG, John

“…To determine the safety and tolerability of ABT-869 at escalating doses and its effects on biomarkers relevant for antiangiogenic activity in patients with…”
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Comparison of the Gastrointestinal Absorption and Bioavailability of Fenofibrate and Fenofibric Acid in Humans by Zhu, Tong, Ansquer, Jean-Claude, Kelly, Maureen T., Sleep, Darryl J., Pradhan, Rajendra S.

“…This study compared the gastrointestinal (GI) absorption characteristics and absolute bioavailability of fenofibric acid and fenofibrate (which is converted to…”
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Paraneoplastic Limbic Encephalitis Mimicking Acute Herpetic Encephalitis by Gupta, Charchit, Chaudhari, Dinesh, Renjen, Pushpendra Nath, Mishra, Anjali, Garg, Shivangi, Pradhan, Rajendra

“…Paraneoplastic limbic encephalitis (PLE) is a rare disorder that typically follows a chronic or subacute course of personality changes, memory loss, seizures,…”
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Studying navitoclax, a targeted anticancer drug, in healthy volunteers--ethical considerations and risk/benefit assessments and management by Xiong, Hao, Pradhan, Rajendra S, Nada, Adel, Krivoshik, Andrew P, Holen, Kyle D, Rhodes, James W, Gordon, Gary B, Humerickhouse, Rod, Awni, Walid M

“…Biopharmaceutical studies for anti-cancer drugs are typically conducted in cancer patients due to unacceptable toxicities to healthy volunteers. Navitoclax is…”
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Edaravone: A New Hope for Patients with Amyotrophic Lateral Sclerosis by Garg, Shivangi, Chaudhari, Dinesh, Renjen, Pushpendra Nath, Mishra, Anjali, Kumar, Abhas, Pradhan, Rajendra

“…Although the exact pathophysiology of amyotrophic lateral sclerosis (ALS) remains unclear, oxidative stress is known to play a pivotal role. There is no cure…”
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Cortical Venous Thrombosis - A Case Series and Review of Recent Updates by Garg, Shivangi, Chaudhari, Dinesh, Renjen, Pushpendra Nath, Ahmad, Kamal, Kumar, Abhas, Pradhan, Rajendra, Mishra, Anjali

“…Thrombosis of the dural sinus and/or cerebral veins (cerebral venous thrombosis [CVT]) is an uncommon form of stroke, usually affecting young individuals…”
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Pharmacokinetic and Exposure–Response Analyses of Leuprolide Following Administration of Leuprolide Acetate 3-Month Depot Formulations to Children with Central Precocious Puberty by Mostafa, Nael M., Hosmane, Balakrishna, Larsen, Lois M., Chwalisz, Kristof, Chiu, Yi-Lin, Pradhan, Rajendra S.

“…Background and Objective A pharmacokinetic substudy was conducted within a phase 3 clinical trial that evaluated the efficacy and safety of two leuprolide…”
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Thermophysical properties of binary mixtures of N,N-dimethylformamide with three cyclic ethers by Sinha Biswajit, Pradhan Rajendra, Saha Sanjoy, Brahman Dhiraj, Sarkar Abhijit

“…Densities and viscosities of the binary mixtures consisting of tetrahydrofuran (THF), 1,3-dioxolane (1,3-DO) and 1,4-dioxane (1,4-DO) with…”
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Sa1210 Relationship Between Adalimumab Concentration and Efficacy for the Induction of Clinical Remission in Pediatric Patients With Moderate to Severe Crohn's Disease by Pradhan, Rajendra S, Sharma, Shringi, Thakkar, Roopal, Robinson, Anne, Hyams, Jeffrey S, Rosh, Joel R, Ruemmele, Frank, Awni, Walid M

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Sa1195 Exposure-Efficacy Relationship (ER) for Adalimumab During Induction Phase of Treatment of Adult Patients With Moderate to Severe Ulcerative Colitis by Mostafa, Nael M, Eckert, Doerthe, Pradhan, Rajendra S, Mensing, Sven, Robinson, Anne, Sandborn, William, Hanauer, Stephen B, Colombel, Jean-Frederic, Thakkar, Roopal, Awni, Walid M

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Sa1212 Relationship Between Adalimumab Concentration and Efficacy for the Maintenance of Clinical Remission in Pediatric Patients With Moderate to Severe Crohn's Disease by Sharma, Shringi, Pradhan, Rajendra S, Thakkar, Roopal, Robinson, Anne, Hyams, Jeffrey S, Rosh, Joel R, Ruemmele, Frank, Awni, Walid M

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Oral paricalcitol for the treatment of secondary hyperparathyroidism in patients on hemodialysis or peritoneal dialysis by Ross, Edward A, Tian, Jin, Abboud, Hanna, Hippensteel, Richard, Melnick, Joel Z, Pradhan, Rajendra S, Williams, Laura A, Hamm, L Lee, Sprague, Stuart M

“…Secondary hyperparathyroidism is a common complication of chronic kidney disease, resulting from inactivation of vitamin D receptor signaling and phosphate…”
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Sa1204 Pharmacokinetics of Adalimumab in Adult Patients With Moderately to Severely Active Ulcerative Colitis by Awni, Walid M, Eckert, Doerthe, Sharma, Shringi, Mostafa, Nael M, Noertersheuser, Peter A, Pradhan, Rajendra S, Robinson, Anne, Sandborn, William, Hanauer, Stephen B, Colombel, Jean-Frederic, Thakkar, Roopal

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Exposure-Clinical Response Analysis of Paricalcitol in Patients With Chronic Kidney Disease (Stage 5) on Hemodialysis or Peritoneal Dialysis by Noertersheuser, Peter A., Pradhan, Rajendra S., Klein, Cheri E., Williams, Laura A., Palaparthy, Rameshraja, Garimella, Tushar S., Lichtenberger, Olaf, Awni, Walid M.

“…Paricalcitol injection and capsules are approved for the prevention and treatment of secondary hyperparathyroidism. Exposure-response analyses were performed…”
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Evaluation of the pharmacokinetics and pharmacodynamics of two leuprolide acetate 45mg 6-month depot formulations in patients with prostate cancer by Mostafa, Nael M, Chwalisz, Kristof, Larsen, Lois, Mattia-Goldberg, Cynthia, Spitz, Aaron, Pradhan, Rajendra S

“…The pharmacokinetics (PK) and pharmacodynamics of two leuprolide acetate (LA) 45mg 6-month depot formulations were characterized in prostate cancer patients…”
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ABT-335, the Choline Salt of Fenofibric Acid, Does Not Have a Clinically Significant Pharmacokinetic Interaction With Rosuvastatin in Humans by Zhu, Tong, Awni, Walid M., Hosmane, Balakrishna, Kelly, Maureen T., Sleep, Darryl J., Stolzenbach, James C., Wan, Katty, Chira, Titus O., Pradhan, Rajendra S.

“…ABT‐335 is the choline salt of fenofibric acid under clinical development as a combination therapy with rosuvastatin for the management of dyslipidemia…”
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