Search Results - "PRACHAND, Sheila N"
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Arsenic trioxide cytotoxicity in steroid and chemotherapy-resistant myeloma cell lines: Enhancement of apoptosis by manipulation of cellular redox state
Published in Clinical cancer research (01-02-2002)“…We investigated the ability of pretreatment with buthionine sulfoximine (BSO) to overcome a priori resistance to arsenic trioxide (As(2)O(3)) in multiple…”
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Journal Article -
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Motexafin Gadolinium Enhances p53-Mdm2 Interactions, Reducing p53 and Downstream Targets in Lymphoma Cell Lines
Published in Anticancer research (01-04-2010)“…Loss of p53 renders cells more susceptible to acute oxidant stress induced by oxidant-generating agents such as motexafin gadolinium (MGd). We hypothesized…”
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Motexafin Gadolinium (MGD) Induces Oxidant Stress and Downregulates Both Pro and Anti-Oxidant Genes in the Ramos Lymphoma Cell Line: Signaling through p53 Mediated Pathways
Published in Blood (16-11-2007)“…We have reported that MGd, an expanded porphyrin and redox stress inducer, lowers p53 protein but not message in lymphoma cell lines. These results suggested…”
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Arsenic Trioxide Cytotoxicity in Steroid and Chemotherapy-resistant Myeloma Cell Lines
Published in Clinical cancer research (01-02-2002)“…Purpose: We investigated the ability of pretreatment with buthionine sulfoximine (BSO) to overcome a priori resistance to arsenic trioxide (As 2 O 3 ) in…”
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Journal Article