Search Results - "POWELL, E"

Nebulosa recovers single-cell gene expression signals by kernel density estimation by Alquicira-Hernandez, Jose, Powell, Joseph E

“…Abstract Summary Data sparsity in single-cell experiments prevents an accurate assessment of gene expression when visualized in a low-dimensional space. Here,…”
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IT'S WHAT YOU MAKE OF IT: FOUNDER IDENTITY AND ENACTING STRATEGIC RESPONSES TO ADVERSITY by POWELL, E. ERIN, BAKER, TED

“…We conducted a longitudinal field study of 13 resource-constrained founder-run textile and apparel firms to understand how and why firms vary in their…”
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IN THE BEGINNING: IDENTITY PROCESSES AND ORGANIZING IN MULTI-FOUNDER NASCENT VENTURES by POWELL, E. ERIN, BAKER, TED

“…We conducted a longitudinal field study of nine nascent ventures attempting to revitalize local municipalities to understand how and why identity processes…”
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scPred: accurate supervised method for cell-type classification from single-cell RNA-seq data by Alquicira-Hernandez, Jose, Sathe, Anuja, Ji, Hanlee P, Nguyen, Quan, Powell, Joseph E

“…Single-cell RNA sequencing has enabled the characterization of highly specific cell types in many tissues, as well as both primary and stem cell-derived cell…”
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Control of Organ Size in Plants by Powell, Anahid E., Lenhard, Michael

“…The size of plant organs, such as leaves and flowers, is determined by an interaction of genotype and environmental influences. Organ growth occurs through the…”
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Advances in the systemic treatment of triple-negative breast cancer by Lebert, J M, Lester, R, Powell, E, Seal, M, McCarthy, J

“…Triple-negative breast cancer constitutes a heterogeneous group of malignancies that are often aggressive and associated with a poor prognosis. Molecular…”
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DropletQC: improved identification of empty droplets and damaged cells in single-cell RNA-seq data by Muskovic, Walter, Powell, Joseph E

“…Advances in droplet-based single-cell RNA-sequencing (scRNA-seq) have dramatically increased throughput, allowing tens of thousands of cells to be routinely…”
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Benchmarking of cell type deconvolution pipelines for transcriptomics data by Avila Cobos, Francisco, Alquicira-Hernandez, José, Powell, Joseph E., Mestdagh, Pieter, De Preter, Katleen

“…Many computational methods have been developed to infer cell type proportions from bulk transcriptomics data. However, an evaluation of the impact of data…”
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Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets by Zhu, Zhihong, Zhang, Futao, Hu, Han, Bakshi, Andrew, Robinson, Matthew R, Powell, Joseph E, Montgomery, Grant W, Goddard, Michael E, Wray, Naomi R, Visscher, Peter M, Yang, Jian

“…Jian Yang and colleagues propose a method that integrates summary data from GWAS and eQTL studies to identify genes whose expression levels are associated with…”
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Structural basis of SARS-CoV-2 Omicron immune evasion and receptor engagement by McCallum, Matthew, Czudnochowski, Nadine, Rosen, Laura E, Zepeda, Samantha K, Bowen, John E, Walls, Alexandra C, Hauser, Kevin, Joshi, Anshu, Stewart, Cameron, Dillen, Josh R, Powell, Abigail E, Croll, Tristan I, Nix, Jay, Virgin, Herbert W, Corti, Davide, Snell, Gyorgy, Veesler, David

“…The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of concern evades antibody-mediated immunity that comes from vaccination or…”
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The influence of perceived host country political risk on foreign subunits' supplier development strategies by Charpin, Remi, Powell, E. Erin, Roth, Aleda V.

“…Recent protectionist trends (e.g., trade wars, Brexit) have challenged the stability of the global supply chains (SCs) of multinational corporations. While the…”
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Socially responsible product-positioning: Impact of halo/horns spillover on product image by Naeeni, Hannan Sadjady, Sahin, Funda, Powell Robinson, E.

“…•Social responsibility has a spillover effect on product-position decisions.•Halo spillover effect can unexpectedly lead to a Prisoner's Dilemma.•The model…”
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3D Chromosome Regulatory Landscape of Human Pluripotent Cells by Ji, Xiong, Dadon, Daniel B., Powell, Benjamin E., Fan, Zi Peng, Borges-Rivera, Diego, Shachar, Sigal, Weintraub, Abraham S., Hnisz, Denes, Pegoraro, Gianluca, Lee, Tong Ihn, Misteli, Tom, Jaenisch, Rudolf, Young, Richard A.

“…In this study, we describe the 3D chromosome regulatory landscape of human naive and primed embryonic stem cells. To devise this map, we identified…”
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Causes and Consequences of Innate Immune Dysfunction in Cirrhosis by Irvine, Katharine Margaret, Ratnasekera, Isanka, Powell, Elizabeth E, Hume, David Arthur

“…Liver cirrhosis is an increasing health burden and public health concern. Regardless of etiology, patients with cirrhosis are at risk of a range of…”
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Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency by Theunissen, Thorold W., Powell, Benjamin E., Wang, Haoyi, Mitalipova, Maya, Faddah, Dina A., Reddy, Jessica, Fan, Zi Peng, Maetzel, Dorothea, Ganz, Kibibi, Shi, Linyu, Lungjangwa, Tenzin, Imsoonthornruksa, Sumeth, Stelzer, Yonatan, Rangarajan, Sudharshan, D’Alessio, Ana, Zhang, Jianming, Gao, Qing, Dawlaty, Meelad M., Young, Richard A., Gray, Nathanael S., Jaenisch, Rudolf

“…Embryonic stem cells (ESCs) of mice and humans have distinct molecular and biological characteristics, raising the question of whether an earlier, “naive”…”
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Physical activity for health: What kind? How much? How intense? On top of what? by Powell, Kenneth E, Paluch, Amanda E, Blair, Steven N

“…Physical activity improves health. Different types of activity promote different types of physiologic changes and different health outcomes. A curvilinear…”
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Single-cell eQTL mapping identifies cell type-specific genetic control of autoimmune disease by Yazar, Seyhan, Alquicira-Hernandez, Jose, Wing, Kristof, Senabouth, Anne, Gordon, M Grace, Andersen, Stacey, Lu, Qinyi, Rowson, Antonia, Taylor, Thomas R P, Clarke, Linda, Maccora, Katia, Chen, Christine, Cook, Anthony L, Ye, Chun Jimmie, Fairfax, Kirsten A, Hewitt, Alex W, Powell, Joseph E

“…The human immune system displays substantial variation between individuals, leading to differences in susceptibility to autoimmune disease. We present…”
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Physical Activity, All-Cause and Cardiovascular Mortality, and Cardiovascular Disease by KRAUS, WILLIAM E, POWELL, KENNETH E, HASKELL, WILLIAM L, JANZ, KATHLEEN F, CAMPBELL, WAYNE W, JAKICIC, JOHN M, TROIANO, RICHARD P, SPROW, KYLE, TORRES, ANDREA, PIERCY, KATRINA L

“…PURPOSEConduct a systematic umbrella review to evaluate the relationship of physical activity (PA) with all-cause mortality, cardiovascular mortality, and…”
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Preserving Both Anion and Cation Sublattice Features during a Nanocrystal Cation-Exchange Reaction: Synthesis of Metastable Wurtzite-Type CoS and MnS by Powell, Anna E, Hodges, James M, Schaak, Raymond E

“…The ability to selectively synthesize one particular polymorph in a solid-state system having multiple crystal structures with the same composition is…”
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Physical Activity, Cognition, and Brain Outcomes: A Review of the 2018 Physical Activity Guidelines by ERICKSON, KIRK I, HILLMAN, CHARLES, STILLMAN, CHELSEA M, BALLARD, RACHEL M, BLOODGOOD, BONNY, CONROY, DAVID E, MACKO, RICHARD, MARQUEZ, DAVID X, PETRUZZELLO, STEVEN J, POWELL, KENNETH E

“…PURPOSEPhysical activity (PA) is known to improve cognitive and brain function, but debate continues regarding the consistency and magnitude of its effects,…”
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