Search Results - "POULSEN, L"

Biomarkers for monitoring clinical efficacy of allergen immunotherapy for allergic rhinoconjunctivitis and allergic asthma: an EAACI Position Paper by Shamji, M. H., Kappen, J. H., Akdis, M., Jensen‐Jarolim, E., Knol, E. F., Kleine‐Tebbe, J., Bohle, B., Chaker, A. M., Till, S. J., Valenta, R., Poulsen, L. K., Calderon, M. A., Demoly, P., Pfaar, O., Jacobsen, L., Durham, S. R., Schmidt‐Weber, C. B.

“…Background Allergen immunotherapy (AIT) is an effective treatment for allergic rhinoconjunctivitis (AR) with or without asthma. It is important to note that…”
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Precision medicine in allergic disease—food allergy, drug allergy, and anaphylaxis—PRACTALL document of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma and Immunology by Muraro, A., Lemanske, R. F., Castells, M., Torres, M. J., Khan, D., Simon, H.‐U., Bindslev‐Jensen, C., Burks, W., Poulsen, L. K., Sampson, H. A., Worm, M., Nadeau, K. C.

“…This consensus document summarizes the current knowledge on the potential for precision medicine in food allergy, drug allergy, and anaphylaxis under the…”
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Targeted therapeutics and novel signaling pathways in non-alcohol-associated fatty liver/steatohepatitis (NAFL/NASH) by Xu, Xiaohan, Poulsen, Kyle L., Wu, Lijuan, Liu, Shan, Miyata, Tatsunori, Song, Qiaoling, Wei, Qingda, Zhao, Chenyang, Lin, Chunhua, Yang, Jinbo

“…Non-alcohol-associated fatty liver/steatohepatitis (NAFL/NASH) has become the leading cause of liver disease worldwide. NASH, an advanced form of NAFL, can be…”
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The epidemiology of food allergy in Europe: a systematic review and meta‐analysis by Nwaru, B. I., Hickstein, L., Panesar, S. S., Muraro, A., Werfel, T., Cardona, V., Dubois, A. E. J., Halken, S., Hoffmann‐Sommergruber, K., Poulsen, L. K., Roberts, G., Van Ree, R., Vlieg‐Boerstra, B. J., Sheikh, A.

“…Food allergy (FA) is an important atopic disease although its precise burden is unclear. This systematic review aimed to provide recent, up‐to‐date data on the…”
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Allergen immunotherapy for IgE‐mediated food allergy: a systematic review and meta‐analysis by Nurmatov, U., Dhami, S., Arasi, S., Pajno, G. B., Fernandez‐Rivas, M., Muraro, A., Roberts, G., Akdis, C., Alvaro‐Lozano, M., Beyer, K., Bindslev‐Jensen, C., Burks, W., Toit, G., Ebisawa, M., Eigenmann, P., Knol, E., Makela, M., Nadeau, K. C., O'Mahony, L., Papadopoulos, N., Poulsen, L. K., Sackesen, C., Sampson, H., Santos, A. F., Ree, R., Timmermans, F., Sheikh, A.

“…Background The European Academy of Allergy and Clinical Immunology (EAACI) is developing Guidelines for Allergen Immunotherapy (AIT) for IgE‐mediated Food…”
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Can we identify patients at risk of life‐threatening allergic reactions to food? by Turner, P. J., Baumert, J. L., Beyer, K., Boyle, R. J., Chan, C.‐H., Clark, A. T., Crevel, R. W. R., DunnGalvin, A., Fernández‐Rivas, M., Gowland, M. H., Grabenhenrich, L., Hardy, S., Houben, G. F., O'B Hourihane, J., Muraro, A., Poulsen, L. K., Pyrz, K., Remington, B. C., Schnadt, S., Ree, R., Venter, C., Worm, M., Mills, E. N. C., Roberts, G., Ballmer‐Weber, B. K.

“…Anaphylaxis has been defined as a ‘severe, life‐threatening generalized or systemic hypersensitivity reaction’. However, data indicate that the vast majority…”
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Effect of Acid Suppressants on the Risk of COVID-19: A Propensity Score-Matched Study Using UK Biobank by Fan, Xiude, Liu, Zhengwen, Miyata, Tatsunori, Dasarathy, Srinivasan, Rotroff, Daniel M., Wu, Xiaoqin, Poulsen, Kyle L., Nagy, Laura E.

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CRISPR-Cas12a nucleases function with structurally engineered crRNAs: SynThetic trAcrRNA by Jedrzejczyk, D. J., Poulsen, L. D., Mohr, M., Damas, N. D., Schoffelen, S., Barghetti, A., Baumgartner, R., Weinert, B. T., Warnecke, T., Gill, R. T.

“…CRISPR-Cas12a systems are becoming an attractive genome editing tool for cell engineering due to their broader editing capabilities compared to CRISPR-Cas9…”
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Position paper of the EAACI: food allergy due to immunological cross‐reactions with common inhalant allergens by Werfel, T., Asero, R., Ballmer‐Weber, B. K., Beyer, K., Enrique, E., Knulst, A. C., Mari, A., Muraro, A., Ollert, M., Poulsen, L. K., Vieths, S., Worm, M., Hoffmann‐Sommergruber, K.

“…In older children, adolescents, and adults, a substantial part of all IgE‐mediated food allergies is caused by cross‐reacting allergenic structures shared by…”
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The non-transcriptional activity of IRF3 modulates hepatic immune cell populations in acute-on-chronic ethanol administration in mice by Sanz-Garcia, Carlos, Poulsen, Kyle L., Bellos, Damien, Wang, Han, McMullen, Megan R., Li, Xiaoxia, Chattopadhyay, Saurabh, Sen, Ganes, Nagy, Laura E.

“…[Display omitted] •Interferon regulatory factor 3 (IRF3) has both transcriptional and non-transcriptional activity.•Gao-binge ethanol exposure increases both…”
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Safety and efficacy of BAY 94‐9027, a prolonged‐half‐life factor VIII by Reding, M. T., Ng, H. J., Poulsen, L. H., Eyster, M. E., Pabinger, I., Shin, H.‐J., Walsch, R., Lederman, M., Wang, M., Hardtke, M., Michaels, L. A.

“…Essentials Recombinant factor VIII BAY 94‐9027 conjugates in a site‐specific manner with polyethylene glycol. BAY 94‐9027 was given to patients with severe…”
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Clinical efficacy of sublingual and subcutaneous birch pollen allergen‐specific immunotherapy: a randomized, placebo‐controlled, double‐blind, double‐dummy study by Khinchi, M. S., Poulsen, L. K., Carat, F., André, C., Hansen, A. B., Malling, H.‐J.

“…Background:  Both sublingual allergen‐specific immunotherapy (SLIT) and subcutaneous immunotherapy (SCIT) have a documented clinical efficacy, but only few…”
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The diagnosis of food allergy: a systematic review and meta‐analysis by Soares‐Weiser, K., Takwoingi, Y., Panesar, S. S., Muraro, A., Werfel, T., Hoffmann‐Sommergruber, K., Roberts, G., Halken, S., Poulsen, L., Ree, R., Vlieg‐Boerstra, B. J., Sheikh, A.

“…Background We investigated the accuracy of tests used to diagnose food allergy. Methods Skin prick tests (SPT), specific‐IgE (sIgE), component‐resolved…”
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Challenges in the implementation of EAACI guidelines on allergen immunotherapy: A global perspective on the regulation of allergen products by Bonertz, A., Roberts, G. C., Hoefnagel, M., Timon, M., Slater, J. E., Rabin, R. L., Bridgewater, J., Pini, C., Pfaar, O., Akdis, C., Goldstein, J., Poulsen, L. K., van Ree, R., Rhyner, C., Barber, D., Palomares, O., Sheikh, A., Pawankar, R., Hamerlijnk, D., Klimek, L., Agache, I., Angier, E., Casale, T., Fernandez‐Rivas, M., Halken, S., Jutel, M., Lau, S., Pajno, G., Sturm, G., Varga, E. M., Gerth van Wijk, R., Bonini, S., Muraro, A., Vieths, S.

“…Regulatory approaches for allergen immunotherapy (AIT) products and the availability of high‐quality AIT products are inherently linked to each other. While…”
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Primary prevention of food allergy in children and adults: systematic review by Silva, D., Geromi, M., Halken, S., Host, A., Panesar, S. S., Muraro, A., Werfel, T., Hoffmann‐Sommergruber, K., Roberts, G., Cardona, V., Dubois, A. E. J., Poulsen, L. K., Van Ree, R., Vlieg‐Boerstra, B., Agache, I., Grimshaw, K., O'Mahony, L., Venter, C., Arshad, S. H., Sheikh, A.

“…Background Food allergies can have serious physical, social, and financial consequences. This systematic review examined ways to prevent the development of…”
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Allergen manufacturing and quality aspects for allergen immunotherapy in Europe and the United States: An analysis from the EAACI AIT Guidelines Project by Bonertz, A., Roberts, G., Slater, J. E., Bridgewater, J., Rabin, R. L., Hoefnagel, M., Timon, M., Pini, C., Pfaar, O., Sheikh, A., Ryan, D., Akdis, C., Goldstein, J., Poulsen, L. K., Ree, R., Rhyner, C., Barber, D., Palomares, O., Pawankar, R., Hamerlijnk, D., Klimek, L., Agache, I., Angier, E., Casale, T., Fernandez‐Rivas, M., Halken, S., Jutel, M., Lau, S., Pajno, G., Sturm, G., Varga, E. M., Gerth van Wijk, R., Bonini, S., Muraro, A., Vieths, S.

“…Adequate quality is essential for any medicinal product to be eligible for marketing. Quality includes verification of the identity, content and purity of a…”
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Updates on the Immune Cell Basis of Hepatic Ischemia-Reperfusion Injury by Heo, Mi Jeong, Suh, Ji Ho, Poulsen, Kyle L, Ju, Cynthia, Kim, Kang Ho

“…Liver ischemia-reperfusion injury (IRI) is the main cause of organ dysfunction and failure after liver surgeries including organ transplantation. The mechanism…”
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SUMO and ubiquitin-dependent XPC exchange drives nucleotide excision repair by van Cuijk, Loes, van Belle, Gijsbert J., Turkyilmaz, Yasemin, Poulsen, Sara L., Janssens, Roel C., Theil, Arjan F., Sabatella, Mariangela, Lans, Hannes, Mailand, Niels, Houtsmuller, Adriaan B., Vermeulen, Wim, Marteijn, Jurgen A.

“…XPC recognizes UV-induced DNA lesions and initiates their removal by nucleotide excision repair (NER). Damage recognition in NER is tightly controlled by…”
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Effects of on-site Supportive Communication Training (On-site SCT) on doctor-patient communication in oncology: Study protocol of a randomized, controlled mixed-methods trial by Kk, Antonsen, At, Johnsen, Lø, Poulsen, Jd, Lyhne, L, Lund, S, Eßer-Naumann, S, Timm, Lh, Jensen

“…The quality of communication in oncology significantly impacts patients' health outcomes, as poor communication increases the risk of unnecessary treatment,…”
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Standardized testing with chlorhexidine in perioperative allergy – a large single‐centre evaluation by Opstrup, M. S., Malling, H.‐J., Krøigaard, M., Mosbech, H., Skov, P. S., Poulsen, L. K., Garvey, L. H.

“…Background Perioperative allergic reactions to chlorhexidine are often severe and easily overlooked. Although rare, the prevalence remains unknown. Correct…”
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