Search Results - "POULSEN, Jens"

Stimulation of Lignocellulosic Biomass Hydrolysis by Proteins of Glycoside Hydrolase Family 61: Structure and Function of a Large, Enigmatic Family by Harris, Paul V, Welner, Ditte, McFarland, K. C, Re, Edward, Navarro Poulsen, Jens-Christian, Brown, Kimberly, Salbo, Rune, Ding, Hanshu, Vlasenko, Elena, Merino, Sandy, Xu, Feng, Cherry, Joel, Larsen, Sine, Lo Leggio, Leila

“…Currently, the relatively high cost of enzymes such as glycoside hydrolases that catalyze cellulose hydrolysis represents a barrier to commercialization of a…”
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Insights into the oxidative degradation of cellulose by a copper metalloenzyme that exploits biomass components by Quinlan, R. Jason, Sweeney, Matt D, Lo Leggio, Leila, Otten, Harm, Poulsen, Jens-Christian N, Johansen, Katja Salomon, Krogh, Kristian B. R. M, Jørgensen, Christian Isak, Tovborg, Morten, Anthonsen, Annika, Tryfona, Theodora, Walter, Clive P, Dupree, Paul, Xu, Feng, Davies, Gideon J, Walton, Paul H

“…The enzymatic degradation of recalcitrant plant biomass is one of the key industrial challenges of the 21st century. Accordingly, there is a continuing drive…”
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Structure and boosting activity of a starch-degrading lytic polysaccharide monooxygenase by Lo Leggio, Leila, Simmons, Thomas J., Poulsen, Jens-Christian N., Frandsen, Kristian E. H., Hemsworth, Glyn R., Stringer, Mary A., von Freiesleben, Pernille, Tovborg, Morten, Johansen, Katja S., De Maria, Leonardo, Harris, Paul V., Soong, Chee-Leong, Dupree, Paul, Tryfona, Theodora, Lenfant, Nicolas, Henrissat, Bernard, Davies, Gideon J., Walton, Paul H.

“…Lytic polysaccharide monooxygenases (LPMOs) are recently discovered enzymes that oxidatively deconstruct polysaccharides. LPMOs are fundamental in the…”
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Structural and biochemical studies of the glucuronoyl esterase OtCE15A illuminate its interaction with lignocellulosic components by Mazurkewich, Scott, Poulsen, Jens-Christian N., Lo Leggio, Leila, Larsbrink, Johan

“…Glucuronoyl esterases (GEs) catalyze the cleavage of ester linkages between lignin and glucuronic acid moieties on glucuronoxylan in plant biomass. As such,…”
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Structural and functional investigation of a fungal member of carbohydrate esterase family 15 with potential specificity for rare xylans by Mazurkewich, Scott, Scholzen, Karoline C., Brusch, Rikke H., Poulsen, Jens-Christian N., Theibich, Yusuf, Hüttner, Silvia, Olsson, Lisbeth, Larsbrink, Johan, Lo Leggio, Leila

“…In plant cell walls, covalent bonds between polysaccharides and lignin increase recalcitrance to degradation. Ester bonds are known to exist between glucuronic…”
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Probing the determinants of the transglycosylation/hydrolysis partition in a retaining α-l-arabinofuranosidase by Zhao, Jiao, Tandrup, Tobias, Bissaro, Bastien, Barbe, Sophie, Poulsen, Jens-Christian N., André, Isabelle, Dumon, Claire, Lo Leggio, Leila, O’Donohue, Michael J., Fauré, Régis

“…[Display omitted] •L352M alters donor and acceptor subsites, causing a domino effect in the active site.•R69 is confirmed as a key determinant of the…”
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Structure of a lytic polysaccharide monooxygenase from Aspergillus fumigatus and an engineered thermostable variant by Lo Leggio, Leila, Weihe, Cecilia D., Poulsen, Jens-Christian N., Sweeney, Matt, Rasmussen, Frank, Lin, Janine, De Maria, Leonardo, Wogulis, Mark

“…Lytic polysaccharide monooxygenases (LPMOs) are industrial enzymes which are gaining use in second generation bioethanol production from lignocellulose by…”
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Polysaccharide utilization loci from Bacteroidota encode CE15 enzymes with possible roles in cleaving pectin-lignin bonds by Seveso, Andrea, Mazurkewich, Scott, Banerjee, Sanchari, Poulsen, Jens-Christian Navarro, Lo Leggio, Leila, Larsbrink, Johan

“…Lignocellulose is a renewable but complex material exhibiting high recalcitrance to enzymatic hydrolysis, which is attributed, in part, to the presence of…”
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Unliganded and substrate bound structures of the cellooligosaccharide active lytic polysaccharide monooxygenase LsAA9A at low pH by Frandsen, Kristian E.H., Poulsen, Jens-Christian N., Tandrup, Tobias, Lo Leggio, Leila

“…Lytic polysaccharide monooxygenases (LPMOs) have been found to be key components in microbial (bacterial and fungal) degradation of biomass. They are copper…”
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Structural and Functional Analysis of a Multimodular Hyperthermostable Xylanase-Glucuronoyl Esterase from Caldicellulosiruptor kristjansonii by Krska, Daniel, Mazurkewich, Scott, Brown, Haley A, Theibich, Yusuf, Poulsen, Jens-Christian N, Morris, Adeline L, Koropatkin, Nicole M, Lo Leggio, Leila, Larsbrink, Johan

“…The hyperthermophilic bacterium Caldicellulosiruptor kristjansonii encodes an unusual enzyme, CkXyn10C-GE15A, which incorporates two catalytic domains, a…”
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The molecular basis of polysaccharide cleavage by lytic polysaccharide monooxygenases by Frandsen, Kristian E H, Simmons, Thomas J, Dupree, Paul, Poulsen, Jens-Christian N, Hemsworth, Glyn R, Ciano, Luisa, Johnston, Esther M, Tovborg, Morten, Johansen, Katja S, von Freiesleben, Pernille, Marmuse, Laurence, Fort, Sébastien, Cottaz, Sylvain, Driguez, Hugues, Henrissat, Bernard, Lenfant, Nicolas, Tuna, Floriana, Baldansuren, Amgalanbaatar, Davies, Gideon J, Lo Leggio, Leila, Walton, Paul H

“…Lytic polysaccharide monooxygenases (LPMOs) are a class of copper-dependent enzymes that oxidatively degrade polysaccharides and find use in industrial…”
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Insights into an unusual Auxiliary Activity 9 family member lacking the histidine brace motif of lytic polysaccharide monooxygenases by Frandsen, Kristian E.H., Tovborg, Morten, Jørgensen, Christian I., Spodsberg, Nikolaj, Rosso, Marie-Noëlle, Hemsworth, Glyn R., Garman, Elspeth F., Grime, Geoffrey W., Poulsen, Jens-Christian N., Batth, Tanveer S., Miyauchi, Shingo, Lipzen, Anna, Daum, Chris, Grigoriev, Igor V., Johansen, Katja S., Henrissat, Bernard, Berrin, Jean-Guy, Lo Leggio, Leila

“…Lytic polysaccharide monooxygenases (LPMOs) are redox-enzymes involved in biomass degradation. All characterized LPMOs possess an active site of two highly…”
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Structure–function analyses reveal that a glucuronoyl esterase from Teredinibacter turnerae interacts with carbohydrates and aromatic compounds by Arnling Bååth, Jenny, Mazurkewich, Scott, Poulsen, Jens-Christian Navarro, Olsson, Lisbeth, Lo Leggio, Leila, Larsbrink, Johan

“…Glucuronoyl esterases (GEs) catalyze the cleavage of ester linkages found between lignin and glucuronic acid moieties on glucuronoxylan in plant biomass. As…”
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An 1,4-α-Glucosyltransferase Defines a New Maltodextrin Catabolism Scheme in Lactobacillus acidophilus by Andersen, Susan, Møller, Marie S, Poulsen, Jens-Christian N, Pichler, Michael J, Svensson, Birte, Lo Leggio, Leila, Goh, Yong Jun, Abou Hachem, Maher

“…The maltooligosaccharide (MOS) utilization locus in NCFM, a model for human small-intestine lactobacilli, encodes three glycoside hydrolases (GHs): a putative…”
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Camel and bovine chymosin: the relationship between their structures and cheese-making properties by Langholm Jensen, Jesper, Mølgaard, Anne, Navarro Poulsen, Jens-Christian, Harboe, Marianne Kirsten, Simonsen, Jens Bæk, Lorentzen, Andrea Maria, Hjernø, Karin, van den Brink, Johannes M., Qvist, Karsten Bruun, Larsen, Sine

“…Bovine and camel chymosin are aspartic peptidases that are used industrially in cheese production. They cleave the Phe105‐Met106 bond of the milk protein…”
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Structure of a hyperthermostable carbonic anhydrase identified from an active hydrothermal vent chimney by Fredslund, Folmer, Borchert, Martin S., Poulsen, Jens-Christian N., Mortensen, Steen Bennike, Perner, Mirjam, Streit, Wolfgang R., Lo Leggio, Leila

“…[Display omitted] •A carbonic anhydrase gene was identified from an hydrothermal vent metagenome.•The gene product LOGACA is a dimeric α-type carbonic…”
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Enzymology and Structure of the GH13_31 Glucan 1,6-α-Glucosidase That Confers Isomaltooligosaccharide Utilization in the Probiotic Lactobacillus acidophilus NCFM by Møller, Marie S, Fredslund, Folmer, Majumder, Avishek, Nakai, Hiroyuki, Poulsen, Jens-Christian N, Lo Leggio, Leila, Svensson, Birte, Abou Hachem, Maher

“…Isomaltooligosaccharides (IMO) have been suggested as promising prebiotics that stimulate the growth of probiotic bacteria. Genomes of probiotic lactobacilli…”
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Synthesis of Isofagomine Derivatives as New Fluorescence pH Indicators/Glycosidase Inhibitors by Wang, Bo, Bogh, Sidsel Ammitzbøll, Poulsen, Jens Christian Navarro, Laursen, Bo W., Bols, Mikael

“…Inhibitor protonation of azasugars of the isofagomine type when bound to enzyme can be investigated using photon induced electron transfer (PET) quenching of…”
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Structure of Aspergillus aculeatus β‐1,4‐galactanase in complex with galactobiose by Torpenholt, Søs, Poulsen, Jens-Christian N., Muderspach, Sebastian Jannick, De Maria, Leonardo, Lo Leggio, Leila

“…β‐1,4‐Galactanases are glycoside hydrolases that are involved in the degradation of pectin and belong to family 53 in the classification of glycoside…”
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Determination of protonation states of iminosugar-enzyme complexes using photoinduced electron transfer by Wang, Bo, Olsen, Jacob Ingemar, Laursen, Bo W, Navarro Poulsen, Jens Christian, Bols, Mikael

“…A series of -alkylated analogues of 1-deoxynojirimycin containing a fluorescent 10-chloro-9-anthracene group in the -alkyl substituent were prepared. The…”
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