Search Results - "POULET, Claire"

Small-conductance calcium-activated potassium (SK) channels contribute to action potential repolarization in human atria by Skibsbye, Lasse, Poulet, Claire, Diness, Jonas Goldin, Bentzen, Bo Hjorth, Yuan, Lei, Kappert, Utz, Matschke, Klaus, Wettwer, Erich, Ravens, Ursula, Grunnet, Morten, Christ, Torsten, Jespersen, Thomas

“…Small-conductance calcium-activated potassium (SK) channels are expressed in the heart of various species, including humans. The aim of the present study was…”
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A new approach to transcription factor screening for reprogramming of fibroblasts to cardiomyocyte-like cells by Protze, Stephanie, Khattak, Shahryar, Poulet, Claire, Lindemann, Dirk, Tanaka, Elly M, Ravens, Ursula

“…Abstract The simultaneous overexpression of several transcription factors has emerged as a successful strategy to convert fibroblasts into other cell types…”
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Late Sodium Current in Human Atrial Cardiomyocytes from Patients in Sinus Rhythm and Atrial Fibrillation by Poulet, Claire, Wettwer, Erich, Grunnet, Morten, Jespersen, Thomas, Fabritz, Larissa, Matschke, Klaus, Knaut, Michael, Ravens, Ursula

“…Slowly inactivating Na+ channels conducting "late" Na+ current (INa,late) contribute to ventricular arrhythmogenesis under pathological conditions. INa,late…”
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Loss of Trex1 in Dendritic Cells Is Sufficient To Trigger Systemic Autoimmunity by Peschke, Katrin, Achleitner, Martin, Frenzel, Kathrin, Gerbaulet, Alexander, Ada, Servi Remzi, Zeller, Nicolas, Lienenklaus, Stefan, Lesche, Mathias, Poulet, Claire, Naumann, Ronald, Dahl, Andreas, Ravens, Ursula, Günther, Claudia, Müller, Werner, Knobeloch, Klaus-Peter, Prinz, Marco, Roers, Axel, Behrendt, Rayk

“…Defects of the intracellular enzyme 3' repair exonuclease 1 (Trex1) cause the rare autoimmune condition Aicardi-Goutières syndrome and are associated with…”
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Associations between dysbiosis-inducing drugs, overall survival and tumor response in patients treated with immune checkpoint inhibitors by Gaucher, Louis, Adda, Leslie, Séjourné, Alice, Joachim, Camille, Guillaume, Chaby, Poulet, Claire, Liabeuf, Sophie, Gras-Champel, Valérie, Masmoudi, Kamel, Houessinon, Aline, Bennis, Youssef, Batteux, Benjamin

“…Background: There are conflicting data on the effects of dysbiosis-inducing drugs, and especially antibiotics (ATBs), on clinical outcomes in patients treated…”
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Impact of the corticosteroid indication and administration route on overall survival and the tumor response after immune checkpoint inhibitor initiation by Gaucher, Louis, Adda, Leslie, Séjourné, Alice, Joachim, Camille, Chaby, Guillaume, Poulet, Claire, Liabeuf, Sophie, Gras-Champel, Valérie, Masmoudi, Kamel, Moreira, Aurélie, Bennis, Youssef, Batteux, Benjamin

“…Background: Based on their indications, systemic corticosteroids appear to negatively affect clinical outcomes in immune checkpoint inhibitor (ICI)-treated…”
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Nanoscale regulation of L-type calcium channels differentiates between ischemic and dilated cardiomyopathies by Sanchez-Alonso, Jose L., Loucks, Alexandra, Schobesberger, Sophie, van Cromvoirt, Ankie M., Poulet, Claire, Chowdhury, Rasheda A., Trayanova, Natalia, Gorelik, Julia

“…Subcellular localization and function of L-type calcium channels (LTCCs) play an important role in regulating contraction of cardiomyocytes. Understanding how…”
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Partial Mechanical Unloading of the Heart Disrupts L-Type Calcium Channel and Beta-Adrenoceptor Signaling Microdomains by Wright, Peter T, Sanchez-Alonso, Jose L, Lucarelli, Carla, Alvarez-Laviada, Anita, Poulet, Claire E, Bello, Sean O, Faggian, Giuseppe, Terracciano, Cesare M, Gorelik, Julia

“…We investigated the effect of partial mechanical unloading (PMU) of the heart on the physiology of calcium and beta-adrenoceptor-cAMP (βAR-cAMP) microdomains…”
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β3-Adrenoceptor redistribution impairs NO/cGMP/PDE2 signalling in failing cardiomyocytes by Schobesberger, Sophie, Wright, Peter T, Poulet, Claire, Sanchez Alonso Mardones, Jose L, Mansfield, Catherine, Friebe, Andreas, Harding, Sian E, Balligand, Jean-Luc, Nikolaev, Viacheslav O, Gorelik, Julia

“…Cardiomyocyte β3-adrenoceptors (β3-ARs) coupled to soluble guanylyl cyclase (sGC)-dependent production of the second messenger 3’,5’-cyclic guanosine…”
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Salvage Immunotherapy With Pembrolizumab in Patients Hospitalized for Life-Threatening Complications of NSCLC by Roborel de Climens, Ferréol, Chouaid, Christos, Poulet, Claire, Leroy, Vincent, Stoven, Luc, Cortot, Alexis Benjamin, Dhalluin, Xavier, Gauvain, Clément

“…It is not known whether patients with NSCLC who are hospitalized because of cancer-related complications are liable to benefit from salvage immunotherapy. This…”
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Atypical cutaneous hyperpigmentation after multiple chemotherapy agents by Dessirier, Fanny, Arnault, Jean-Philippe, Farre, Isabelle, Poulet, Claire, Chaby, Guillaume, Dairi, Motaz, Lok, Catherine

“…We report a case of cutaneous hyperpigmentation after injection of cisplatin, carboplatin, pemetrexed, and bevacizumab in patient treated for stage IV lung…”
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Atrial selectivity of antiarrhythmic drugs by Ravens, Ursula, Poulet, Claire, Wettwer, Erich, Knaut, Michael

“…New antiarrhythmic drugs for treatment of atrial fibrillation should ideally be atrial selective in order to avoid pro‐arrhythmic effects in the ventricles…”
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Junctophilin-2 tethers T-tubules and recruits functional L-type calcium channels to lipid rafts in adult cardiomyocytes by Poulet, Claire, Sanchez-Alonso, Jose, Swiatlowska, Pamela, Mouy, Florence, Lucarelli, Carla, Alvarez-Laviada, Anita, Gross, Polina, Terracciano, Cesare, Houser, Steven, Gorelik, Julia

“…Abstract Aim In cardiomyocytes, transverse tubules (T-tubules) associate with the sarcoplasmic reticulum (SR), forming junctional membrane complexes (JMCs)…”
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Rapid Improvement After Starting Elexacaftor-tezacaftor-ivacaftor in Patients with Cystic Fibrosis and Advanced Pulmonary Disease by Burgel, Pierre-Régis, Durieu, Isabelle, Chiron, Raphaël, Ramel, Sophie, Danner-Boucher, Isabelle, Prevotat, Anne, Grenet, Dominique, Marguet, Christophe, Reynaud-Gaubert, Martine, Macey, Julie, Mely, Laurent, Fanton, Annlyse, Quetant, Sébastien, Lemonnier, Lydie, Paillasseur, Jean-Louis, Da Silva, Jennifer, Martin, Clémence

“…Elexacaftor-tezacaftor-ivacaftor is a cystic fibrosis transmembrane conductance regulator modulator combination, developed for cystic fibrosis (CF) patients…”
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Weekly paclitaxel plus bevacizumab versus docetaxel as second- or third-line treatment in advanced non-squamous non–small-cell lung cancer: Results of the IFCT-1103 ULTIMATE study by Cortot, Alexis B., Audigier-Valette, Clarisse, Molinier, Olivier, Le Moulec, Sylvestre, Barlesi, Fabrice, Zalcman, Gérard, Dumont, Patrick, Pouessel, Damien, Poulet, Claire, Fontaine-Delaruelle, Clara, Hiret, Sandrine, Dixmier, Adrien, Renault, Patrick-Aldo, Becht, Catherine, Raffy, Olivier, Dayen, Charles, Mazieres, Julien, Pichon, Eric, Langlais, Alexandra, Morin, Franck, Moro-Sibilot, Denis, Besse, Benjamin

“…Second-line chemotherapy regimens have demonstrated poor benefit after failure of platinum-based chemotherapy in advanced non-squamous non–small-cell lung…”
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Real-Life Safety and Effectiveness of Lumacaftor-Ivacaftor in Patients with Cystic Fibrosis by Burgel, Pierre-Régis, Munck, Anne, Durieu, Isabelle, Chiron, Raphaël, Mely, Laurent, Prevotat, Anne, Murris-Espin, Marlene, Porzio, Michele, Abely, Michel, Reix, Philippe, Marguet, Christophe, Macey, Julie, Sermet-Gaudelus, Isabelle, Corvol, Harriet, Bui, Stéphanie, Lemonnier, Lydie, Dehillotte, Clémence, Da Silva, Jennifer, Paillasseur, Jean-Louis, Hubert, Dominique

“…Lumacaftor-ivacaftor is a CFTR (cystic fibrosis transmembrane conductance regulator) modulator combination recently approved for patients with cystic fibrosis…”
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Interaction of the Joining Region in Junctophilin-2 With the L-Type Ca2+ Channel Is Pivotal for Cardiac Dyad Assembly and Intracellular Ca2+ Dynamics by Gross, Polina, Johnson, Jaslyn, Romero, Carlos M., Eaton, Deborah M., Poulet, Claire, Sanchez-Alonso, Jose, Lucarelli, Carla, Ross, Jean, Gibb, Andrew A., Garbincius, Joanne F., Lambert, Jonathan, Varol, Erdem, Yang, Yijun, Wallner, Markus, Feldsott, Eric A., Kubo, Hajime, Berretta, Remus M., Yu, Daohai, Rizzo, Victor, Elrod, John, Sabri, Abdelkarim, Gorelik, Julia, Chen, Xiongwen, Houser, Steven R.

“…Ca2+-induced Ca2+ release (CICR) in normal hearts requires close approximation of L-type calcium channels (LTCCs) within the transverse tubules (T-tubules) and…”
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Rheumatic and musculoskeletal disorders induced by immune checkpoint inhibitors: Consequences on overall survival by Adda, Leslie, Batteux, Benjamin, Saidak, Zuzana, Poulet, Claire, Arnault, Jean-Philippe, Chauffert, Bruno, Séjourné, Alice

“…Immune checkpoint inhibitors (ICIs) frequently induce immune related adverse events (irAEs) that may be associated with more favorable clinical outcomes. We…”
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Circulating tumour cells as a potential biomarker for lung cancer screening: a prospective cohort study by Marquette, Charles-Hugo, Boutros, Jacques, Benzaquen, Jonathan, Ferreira, Marion, Pastre, Jean, Pison, Christophe, Padovani, Bernard, Bettayeb, Faiza, Fallet, Vincent, Guibert, Nicolas, Basille, Damien, Ilie, Marius, Hofman, Véronique, Hofman, Paul, MARQUETTE, Charles-Hugo, BOUTROS, Jacques, Benzaquen, Jonathan, FERREIRA, Marion, PASTRE, Jean, Pison, Christophe, PADOVANI, Bernard, BETTAYEB, Faiza, FALLET, Vincent, GUIBERT, Nicolas, BASILLE, Damien, ILIE, Marius, HOFMAN, Véronique, HOFMAN, Paul, ISRAEL-BIET, Dominique, CHABOT, François, GUILLAUMOT, Anne, DESLEE, Gaetan, PEROTIN, Jeanne-Marie, DURY, Sandra, MAL, Hervé, MARCEAU, Armelle, Kessler, Romain, Vergnon, Jean-Michel, Pelissier, Carole, Di Palma, Fabrice, Cuvelier, Antoine, PATOUT, Maxime, Bourdin, Arnaud, GAMEZ, Anne Sophie, ANDREJAK, Claire, POULET, Claire, FRANCOIS, Géraldine, Jounieaux, Vincent, Roche, Nicolas, Jouneau, Stéphane, Brinchault, Graziella, Bonniaud, Philippe, ZOUAK, Ayoub, Scherpereel, Arnaud, BALDACCI, Simon, CORTOT, Alexis, Mornex, Jean François, Steenhouwer, François, LEROY, Sylvie, BERTHET, Jean-Philippe, FONTAS, Eric, BULSEI, Julie, CRUZEL, Coralie, Pradelli, Johanna, Fontaine, Maureen, MANIEL, Charlotte, Griffonnet, Jennifer, BUTORI, Catherine, SELVA, Eric, POUDENX, Michel, AguilanIu, Bernard, Ferretti, Gilbert, Arbib, François, Briault, Amandine, Toffart, Anne-Claire, Dahalani, Raissa, Destors, Marie, Chanez, Pascal, GREILLIER, Laurent, ASTOUL, Philippe, BARLESI, Fabrice, GAUBERT, Jean-Yves, Mazières, Julien, Marchand-Adam, Sylvain, Cadranel, Jacques, CHAABANE, Nouha, IZADIFAR, Armine, ROSENCHER, Lise, RUPPERT, Anne-Marie, VIEIRA, Thibault, MATHIOT, Nathalie

“…Lung cancer screening with low-dose chest CT (LDCT) reduces the mortality of eligible individuals. Blood signatures might act as a standalone screening tool,…”
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T-tubule remodelling disturbs localized β2-adrenergic signalling in rat ventricular myocytes during the progression of heart failure by Schobesberger, Sophie, Wright, Peter, Tokar, Sergiy, Bhargava, Anamika, Mansfield, Catherine, Glukhov, Alexey V, Poulet, Claire, Buzuk, Andrey, Monszpart, Aron, Sikkel, Markus, Harding, Sian E, Nikolaev, Viacheslav O, Lyon, Alexander R, Gorelik, Julia

“…Cardiomyocyte β2-adrenergic receptor (β2AR) cyclic adenosine monophosphate (cAMP) signalling is regulated by the receptors' subcellular location within…”
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