Search Results - "POULAIN, B"

Inhibition promotes long-term potentiation at cerebellar excitatory synapses by Binda, F., Dorgans, K., Reibel, S., Sakimura, K., Kano, M., Poulain, B., Isope, P.

“…The ability of the cerebellar cortex to learn from experience ensures the accuracy of movements and reflex adaptation, processes which require long-term…”
Get full text

Botulinum neurotoxin by Poulain, B

“…Botulinum toxin is a multi-molecular complex comprised of a neuro-active moiety (i.e. botulinum neurotoxin) and several associated non-toxic proteins. The…”
Get full text

Pore-forming epsilon toxin causes membrane permeabilization and rapid ATP depletion-mediated cell death in renal collecting duct cells by Chassin, C, Bens, M, de Barry, J, Courjaret, R, Bossu, J L, Cluzeaud, F, Ben Mkaddem, S, Gibert, M, Poulain, B, Popoff, M R, Vandewalle, A

“…Clostridium perfringens epsilon toxin (ET) is a potent pore-forming cytotoxin causing fatal enterotoxemia in livestock. ET accumulates in brain and kidney,…”
Get more information

The staphylococcal Panton and Valentine Leukocidin and γ-haemolysin HlgC/HlgB share C5aR as a receptor, but operate diverse intracellular activities in human polymorphonuclear neutrophils by Zimmermann-Meisse, G., Tawk, M.Y., Bossu, J.-L., Potrich, C., Bourcier, T., Dalla Serra, M., Poulain, B., Prevost, G., Jover, E.

Get full text

Synapsin Controls Both Reserve and Releasable Synaptic Vesicle Pools during Neuronal Activity and Short-Term Plasticity in Aplysia by Humeau, Yann, Doussau, Frederic, Vitiello, Francesco, Greengard, Paul, Benfenati, Fabio, Poulain, Bernard

“…Neurotransmitter release is a highly efficient secretory process exhibiting resistance to fatigue and plasticity attributable to the existence of distinct…”
Get full text

La neurotoxine botulinique by Poulain, B.

“…La toxine botulinique est un complexe multimoléculaire comprenant une entité neuroactive -la neurotoxine botulinique- et des protéines associées, non…”
Get full text

Tetanus toxin is a zinc protein and its inhibition of neurotransmitter release and protease activity depend on zinc by Schiavo, G., Poulain, B., Rossetto, O., Benfenati, F., Tauc, L., Montecucco, C.

“…Tetanus and botulinum neurotoxins are the most potent toxins known. They bind to nerve cells, penetrate the cytosol and block neurotransmitter release…”
Get full text

Mechanisms of action of botulinum toxins and neurotoxins by Poulain, B, Lonchamp, E, Jover, E, Popoff, M R, Molgó, J

“…Several bacteria of the Clostridium genus (C. botulinum) produce 150 kDa di-chainal protein toxins referred as botulinum neurotoxins or BoNTs. They associate…”
Get full text

A reminder of the structure and function of the skeletal neuromuscular junction by Molgó, J, Colasante, C, Benoit, E, Poulain, B

“…The skeletal neuromuscular junction has been considered as a model of chemical synapses due to its relatively simple organization. It is made up of three…”
Get full text

A role for the interchain disulfide or its participating thiols in the internalization of botulinum neurotoxin A revealed by a toxin derivative that binds to ecto-acceptors and inhibits transmitter release intracellularly by DE PAIVA, A, POULAIN, B, LAWRENCE, G. W, SHONE, C. C, TAUC, L, DOLLY, J. O

“…Botulinum neurotoxin type A consists of a disulfide-linked light and heavy chain, with an intradisulfide present within the C-terminal half of the latter. The…”
Get full text

Mécanismes d’action des toxines et neurotoxines botuliques by Poulain, B., Lonchamp, E., Jover, E., Popoff, M.R., Molgó, J.

“…Les neurotoxines botuliques (BoNTs, 7 sérotypes, A-G) sont des protéines produites par des bactéries du genre Clostridium. Les BoNTs sont associées à des…”
Get full text

Rappels structuraux et fonctionnels de la jonction neuromusculaire squelettique by Molgó, J., Colasante, C., Benoit, E., Poulain, B.

“…La jonction neuromusculaire squelettique est considérée comme un modèle de synapses à transmission chimique en raison de son organisation relativement simple…”
Get full text

Minimal essential domains specifying toxicity of the light chains of tetanus toxin and botulinum neurotoxin type A by KURAZONO, H, MOCHIDA, S, BINZ, T, EISEL, U, QUANZ, M, GREBENSTEIN, O, WERNARS, K, POULAIN, B, TAUC, L, NIEMANN, H

“…To define conserved domains within the light (L) chains of clostridial neurotoxins, we determined the sequence of botulinum neurotoxin type B (BoNT/B) and…”
Get full text

In vitro physiological studies on clostridial neurotoxins. Biological models and procedures for extracellular and intracellular application of toxins by Poulain, B, Bader, M F, Molgó, J

Get more information

Neurotransmitter Release is Blocked Intracellularly by Botulinum Neurotoxin, and this Requires Uptake of Both Toxin Polypeptides by a Process Mediated by the Larger Chain by Poulain, B., Tauc, L., Maisey, E. A., Wadsworth, J. D. F., Mohan, P. M., Dolly, J. O.

“…Botulinum neurotoxins (types A and B), which are microbial proteins consisting of two disulfide-linked chains, inhibit specifically and with high potency the…”
Get full text

Quantal neurotransmitter release and the clostridial neurotoxins' targets by Poulain, B, Molgó, J, Thesleff, S

Get more information

The metallo-proteinase activity of tetanus and botulism neurotoxins by Rossetto, O, Deloye, F, Poulain, B, Pellizzari, R, Schiavo, G, Montecucco, C

“…Tetanus and botulinum neurotoxins are produced by several Clostridia and cause the paralytic syndromes of tetanus and botulism by blocking neurotransmitter…”
Get full text

How botulinum and tetanus neurotoxins block neurotransmitter release by Humeau, Yann, Doussau, Frédéric, Grant, Nancy J, Poulain, Bernard

“…Botulinum neurotoxins (BoNT, serotypes A-G) and tetanus neurotoxin (TeNT) are bacterial proteins that comprise a light chain ( M r ≈50) disulfide linked to a…”
Get full text

Heterologous combinations of heavy and light chains from botulinum neurotoxin A and tetanus toxin inhibit neurotransmitter release in Aplysia by POULAIN, B, MOCHIDA, S, WELLER, U, HOGY, B, HABERMANN, E, WADSWORTH, J. D. F, SHONE, C. C, DOLLY, J. O, TAUC, L

“…The neuroparalytic activities of botulinum neurotoxin type A (BoNT A), tetanus toxin (TeTx), or homologous and heterologous combinations of their constituent…”
Get full text

On the Shaping of Circumstellar Envelopes by Pascoli, G., Leclercq, J., Poulain, B.

“…In this paper, we examine the evolutionary process of expansion of a magnetized ring of cool matter ejected from a red giant. The subsequent formation of a…”
Get full text