Search Results - "POUDRIER, Johanne"
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Marginal Zone B-Cell Populations and Their Regulatory Potential in the Context of HIV and Other Chronic Inflammatory Conditions
Published in International journal of molecular sciences (21-03-2022)“…Inflammation in the context of Human Immunodeficiency Virus (HIV) establishes early and persists beyond antiretroviral therapy (ART). As such, we have shown…”
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Natural killer cell phenotype is altered in HIV-exposed seronegative women
Published in PloS one (01-09-2020)“…Highly exposed seronegative (HESN) individuals present a unique setting to study mechanisms of protection against HIV acquisition. As natural killer (NK) cell…”
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3
Natural Immunity to HIV: A Template for Vaccine Strategies
Published in Viruses (23-04-2018)“…Africa accounts for the majority of global human immunodeficiency virus (HIV) infections, most of which affect women through heterosexual intercourse…”
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Excess BAFF Alters NR4As Expression Levels and Breg Function of Human Precursor-like Marginal Zone B-Cells in the Context of HIV-1 Infection
Published in International journal of molecular sciences (01-12-2022)“…We have reported excess B-cell activating factor (BAFF) in the blood of HIV-infected progressors, which was concomitant with increased frequencies of…”
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Vaccination after developing long COVID: Impact on clinical presentation, viral persistence, and immune responses
Published in International journal of infectious diseases (01-11-2023)“…•COVID-19 vaccination post-COVID-19 conditions (PCC) reduced the number of symptoms and increased well-being.•COVID-19 vaccination post-PCC down-regulated…”
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Natural Immunity to HIV is associated with Low BLyS/BAFF levels and low frequencies of innate marginal zone like CD1c+ B-cells in the genital tract
Published in PLoS pathogens (01-06-2019)“…BLyS/BAFF is recognized for its role in B-cell ontogenesis, as well as cell fate decision towards the first-line/innate marginal zone (MZ) B-cell pool. Excess…”
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Excess BAFF May Impact HIV-1-Specific Antibodies and May Promote Polyclonal Responses Including Those from First-Line Marginal Zone B-Cell Populations
Published in Current issues in molecular biology (19-12-2023)“…We have previously shown that blood levels of B-cell Activating Factor (BAFF) rise relatively to disease progression status in the context of HIV-1 infection…”
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Dendritic cell status modulates the outcome of HIV-related B cell disease progression
Published in PLoS pathogens (01-08-2011)“…Do Dendritic Cells Drive B Cell Dysregulation in the Context of HIV Disease Progression? B lymphocyte disorders are important consequences of HIV infection…”
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Monocyte Gene and Molecular Expression Profiles Suggest Distinct Effector and Regulatory Functions in Beninese HIV Highly Exposed Seronegative Female Commercial Sex Workers
Published in Viruses (10-02-2022)“…We have previously reported that the female genital tract (FGT) of Beninese HIV highly-exposed seronegative (HESN) commercial sex workers (CSWs), presented…”
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The Importance of Regulation in Natural Immunity to HIV
Published in Vaccines (Basel) (18-03-2021)“…Worldwide, most Human Immunodeficiency Virus (HIV) infections are acquired through heterosexual intercourse, and in sub-Saharan Africa, 59% of new HIV…”
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HIV Infection Affects Blood Myeloid Dendritic Cells after Successful Therapy and despite Nonprogressing Clinical Disease
Published in The Journal of infectious diseases (01-04-2009)“…We assessed the longitudinal changes in blood myeloid dendritic cell (mDC) and plasmacytoid dendritic cell (pDC) populations in subjects with primary human…”
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High expression levels of BLyS/BAFF by blood dendritic cells and granulocytes are associated with B-cell dysregulation in SIV-infected rhesus macaques
Published in PloS one (24-06-2015)“…Dendritic cells (DCs) modulate B-cell survival and differentiation, mainly through production of growth factors such as B lymphocyte stimulator (BLyS/BAFF). In…”
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Subclinical Atherosclerosis Is Associated with Discrepancies in BAFF and APRIL Levels and Altered Breg Potential of Precursor-like Marginal Zone B-Cells in Long-Term HIV Treated Individuals
Published in Vaccines (Basel) (30-12-2022)“…Chronic inflammation persists in people living with HIV (PLHIV) despite antiretrovial therapy (ART) and is involved in their premature development of…”
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Fluctuations in Blood Marginal Zone B-Cell Frequencies May Reflect Migratory Patterns Associated with HIV-1 Disease Progression Status
Published in PloS one (20-05-2016)“…We have previously shown that overexpression of BLyS/BAFF was associated with increased relative frequencies of innate "precursor" marginal zone (MZ)-like…”
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IL-10 and lymphotoxin-α expression profiles within marginal zone-like B-cell populations are associated with control of HIV-1 disease progression
Published in PloS one (08-07-2014)“…Understanding how the immune system facilitates or controls HIV-1 disease progression has important implications for the design of effective interventions. We…”
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Short communication: Anti-HIV-1 envelope immunoglobulin Gs in blood and cervicovaginal samples of Beninese commercial sex workers
Published in AIDS research and human retroviruses (01-11-2014)“…Characterization of the immune correlates of protection against HIV infection is crucial for the development of preventive strategies. This study examined…”
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Natural Immunity to HIV : A Delicate Balance between Strength and Control
Published in Clinical & developmental immunology (01-01-2012)“…Understanding how the mucosal immune system in the human female reproductive tract might prevent or facilitate HIV infection has important implications for the…”
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High level of soluble HLA-G in the female genital tract of Beninese commercial sex workers is associated with HIV-1 infection
Published in PloS one (23-09-2011)“…Most HIV infections are transmitted across mucosal epithelium. Understanding the role of innate and specific mucosal immunity in susceptibility or protection…”
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NR4A Expression by Human Marginal Zone B-Cells
Published in Antibodies (Basel) (11-10-2019)“…We have previously characterized a human blood CD19 CD1c IgM CD27 CD21 CD10 innate-like B-cell population, which presents features shared by both transitional…”
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Naturally-occurring genetic variants in human DC-SIGN increase HIV-1 capture, cell-transfer and risk of mother-to-child transmission
Published in PloS one (10-07-2012)“…Mother-to-child transmission (MTCT) is the main cause of HIV-1 infection in children worldwide. Dendritic cell-specific ICAM-3 grabbing-nonintegrin (DC-SIGN,…”
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