Search Results - "POTSE, MARK"
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Scalable and Accurate ECG Simulation for Reaction-Diffusion Models of the Human Heart
Published in Frontiers in physiology (20-04-2018)“…Realistic electrocardiogram (ECG) simulation with numerical models is important for research linking cellular and molecular physiology to clinically observable…”
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The ‘Digital Twin’ to enable the vision of precision cardiology
Published in European heart journal (21-12-2020)“…Abstract Providing therapies tailored to each patient is the vision of precision medicine, enabled by the increasing ability to capture extensive data about…”
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Fibrosis and Conduction Abnormalities as Basis for Overlap of Brugada Syndrome and Early Repolarization Syndrome
Published in International journal of molecular sciences (04-02-2021)“…Brugada syndrome and early repolarization syndrome are both classified as J-wave syndromes, with a similar mechanism of arrhythmogenesis and with the same…”
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Differences in ventricular wall composition may explain inter-patient variability in the ECG response to variations in serum potassium and calcium
Published in Frontiers in physiology (11-10-2023)“…Objective: Chronic kidney disease patients have a decreased ability to maintain normal electrolyte concentrations in their blood, which increases the risk for…”
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Epicardial Fibrosis Explains Increased Endo-Epicardial Dissociation and Epicardial Breakthroughs in Human Atrial Fibrillation
Published in Frontiers in physiology (21-02-2020)“…Atrial fibrillation (AF) is accompanied by progressive epicardial fibrosis, dissociation of electrical activity between the epicardial layer and the…”
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Monitoring of Serum Potassium and Calcium Levels in End-Stage Renal Disease Patients by ECG Depolarization Morphology Analysis
Published in Sensors (Basel, Switzerland) (12-04-2022)“…Non-invasive estimation of serum potassium, [K+], and calcium, [Ca2+], can help to prevent life-threatening ventricular arrhythmias in patients with advanced…”
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Evaluation of a Rapid Anisotropic Model for ECG Simulation
Published in Frontiers in physiology (02-05-2017)“…State-of-the-art cardiac electrophysiology models that are able to deliver physiologically motivated activation maps and electrocardiograms (ECGs) can only be…”
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Impact of the Endocardium in a Parameter Optimization to Solve the Inverse Problem of Electrocardiography
Published in Frontiers in physiology (22-01-2019)“…Electrocardiographic imaging aims at reconstructing cardiac electrical events from electrical signals measured on the body surface. The most common approach…”
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Why Ablation of Sites With Purkinje Activation Is Antiarrhythmic: The Interplay Between Fast Activation and Arrhythmogenesis
Published in Frontiers in physiology (23-03-2021)“…Ablation of sites showing Purkinje activity is antiarrhythmic in some patients with idiopathic ventricular fibrillation (iVF). The mechanism for the…”
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ST segment elevation by current-to-load mismatch: an experimental and computational study
Published in Heart rhythm (2011)“…Background Recently, we demonstrated that ajmaline caused ST segment elevation in the heart of an SCN5A mutation carrier by excitation failure in structurally…”
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In vivo electromechanical assessment of heart failure patients with prolonged QRS duration
Published in Heart rhythm (01-06-2015)“…Background Combined measurement of electrical activation and mechanical dyssynchrony in heart failure (HF) patients is scarce but may contain important…”
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Mechanoelectrical coupling enhances initiation and affects perpetuation of atrial fibrillation during acute atrial dilation
Published in Heart rhythm (01-03-2011)“…Background Acute atrial dilation increases the susceptibility to atrial fibrillation (AF). However, the mechanisms by which atrial stretch may contribute to…”
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13
Critical appraisal of the mechanism underlying J waves
Published in Journal of electrocardiology (01-09-2013)“…In this article we briefly discuss the genesis of electrocardiographic waveforms in general, potential mechanisms of J wave formation, and methods to…”
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An in-silico analysis of the effect of heart position and orientation on the ECG morphology and vectorcardiogram parameters in patients with heart failure and intraventricular conduction defects
Published in Journal of electrocardiology (01-07-2015)“…Abstract Aim The aim of this study was to investigate the influence of geometrical factors on the ECG morphology and vectorcardiogram (VCG) parameters. Methods…”
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The effect of reduced intercellular coupling on electrocardiographic signs of left ventricular hypertrophy
Published in Journal of electrocardiology (01-09-2011)“…Abstract Background The electrocardiographic (ECG) diagnosis of left ventricular hypertrophy (LVH) is based on the assumption that QRS voltage increases with…”
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P-wave complexity in normal subjects and computer models
Published in Journal of electrocardiology (01-07-2016)“…Abstract Background P waves reported in electrocardiology literature uniformly appear smooth. Computer simulation and signal analysis studies have shown much…”
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Reduced Sodium Current in the Lateral Ventricular Wall Induces Inferolateral J-Waves
Published in Frontiers in physiology (26-08-2016)“…J-waves in inferolateral leads are associated with a higher risk for idiopathic ventricular fibrillation. We aimed to test potential mechanisms (depolarization…”
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The Early Repolarization Pattern
Published in Journal of the American College of Cardiology (28-07-2015)“…Abstract The term early repolarization has been in use for more than 50 years. This electrocardiographic pattern was considered benign until 2008, when it was…”
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Computer simulation of ECG manifestations of left ventricular electrical remodeling
Published in Journal of electrocardiology (01-11-2012)“…Abstract An increased QRS voltage is considered to be specific for the electrocardiogram (ECG) diagnosis of left ventricular hypertrophy (LVH). However, the…”
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Early repolarization patterns: The good, the bad, and the ugly?
Published in Heart rhythm (01-02-2012)Get full text
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