Search Results - "PORTOUKALIAN, J"

The lipid alterations in the stratum corneum of dogs with atopic dermatitis are alleviated by topical application of a sphingolipid-containing emulsion by Popa, I., Remoue, N., Osta, B., Pin, D., Gatto, H., Haftek, M., Portoukalian, J.

“…Summary Background.  Atopic dermatitis (AD) results from an altered skin barrier associated with defects in the lipid composition of the skin. Dogs with AD…”
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A procedure for fractionation of sphingolipid classes by solid-phase extraction on aminopropyl cartridges by Bodennec, J, Koul, O, Aguado, I, Brichon, G, Zwingelstein, G, Portoukalian, J

“…Solid-phase extraction (SPE) methods are easy, rapid, and reliable. Their growing popularity is in part due to their operational simplicity and cost reduction…”
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Different mechanisms are involved in apoptosis induced by melanoma gangliosides on human monocyte-derived dendritic cells by Bennaceur, Karim, Popa, Iuliana, Chapman, Jessica Alice, Migdal, Camille, Péguet-Navarro, Josette, Touraine, Jean-Louis, Portoukalian, Jacques

“…Tumor escape is linked to multiple mechanisms, notably the liberation, by tumor cells, of soluble factors that inhibit the function of dendritic cells (DC). We…”
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The weak rate of sphingolipid biosynthesis shown by basal keratinocytes isolated from aged vs. young donors is fully rejuvenated after treatment with peptides of a potato hydrolysate by Popa, I., Abdul-Malak, N., Portoukalian, J.

“…Synopsis A new study was carried out to bring more information on the effect of the potato proteins ferment. Basal keratinocytes obtained from freshly excised…”
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Occurrence of ceramides and neutral glycolipids with unusual long-chain base composition in purified rat liver mitochondria by Ardail, D, Popa, I, Alcantara, K, Pons, A, Zanetta, J.P, Louisot, P, Thomas, L, Portoukalian, J

“…The free ceramide content of rat liver mitochondria was found to be 1.7 nmol/mg protein and outer membranes contained a three-fold higher concentration than…”
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Immunogenity of Glycolipids by Portoukalian, Jacques

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Studies of compounds that enhance sphingolipid metabolism in human keratinocytes by Popa, I., Bennaceur, K., Abdul-Malak, N., Perrier, E., Schmitt, D., Portoukalian, J.

“…Several products are known to inhibit the biosynthesis of ceramides and glucosylceramides, but very few stimulate this process. We studied the influence of a…”
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Subcellular distribution and metabolic fate of exogenous ceramides taken up by HL-60 cells by Ardail, D, Popa, I, Bodennec, J, Famy, C, Louisot, P, Portoukalian, J

“…Ceramides (Cer) are key intermediates in the metabolism of sphingomyelin and are also important second messengers. We report that natural long-chain ceramides…”
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Purification of sphingolipid classes by solid-phase extraction with aminopropyl and weak cation exchanger cartridges by Bodennec, J, Brichon, G, Zwingelstein, G, Portoukalian, J

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Distribution of exogenously added gangliosides in serum proteins depends on the relative affinity of albumin and lipoproteins by Rebbaa, A, Portoukalian, J

“…Gangliosides in normal serum are found only in lipoproteins and the relative content of the three major lipoprotein fractions is low density lipoprotein > high…”
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A set of glycoproteins recognized by A2B5 antibody with major bands at 55 and 76 kDa is overexpressed in human head and neck squamous cell carcinomas by Bolot, G, Popa, I, Paret, M.J, David, M.J, Schmitt, D, Portoukalian, J

“…A2B5 antibody was found to strongly label frozen sections of human head and neck squamous cell carcinomas. The low amount of glycolipids (c-series gangliosides…”
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Purification of Free Sphingoid Bases by Solid-Phase Extraction on Weak Cation Exchanger Cartridges by Bodennec, Jacques, Famy, Cécile, Brichon, Gérard, Zwingelstein, Georges, Portoukalian, Jacques

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Deficiency of ganglioside biosynthesis in metastatic human melanoma cells: relevance of CMP-NeuAc:LacCer alpha 2-3 sialyltransferase (GM3 synthase) by Zebda, N, Pedron, S, Rebbaa, A, Portoukalian, J, Berthier-Vergnes, O

“…The glycosphingolipid patterns were analyzed on two clones derived from a human melanoma cell line and selected for their respectively high and low metastatic…”
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Differential labelling of sphingolipids by [ 3H]serine and ([ 3H]methyl)-methionine in fish leukocytes by Bodennec, J, Brichon, G, Koul, O, Portoukalian, J, Zwingelstein, G

“…Long chain bases are constituents of all sphingolipids and their biosynthesis is presumed to occur via the initial condensation of serine with palmitoyl-CoA…”
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The gangliosides as a possible molecular coupling factor between the proportion of radiosensitive cells in vitro and the metastatic potential in vivo within a human melanoma cell line by THOMAS, C. P, BURONFOSSE, A, PORTOUKALIAN, J, FERTIL, B

“…With an experimental model of spontaneous lung metastases in immunosuppressed newborn rats, seven clones and variants with different metastatic potential and…”
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Two monoclonal anticarbohydrate antibodies directed to glycosphingolipids with a lacto-N-glycosyl type II chain by W W Young, Jr, J Portoukalian, S Hakomori

“…Two monoclonal antibodies directed to the Type II carbohydrate chain of glycosphingolipids have been prepared by the murine hybridoma technique. Their…”
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Effects of L-thyroxine on incorporation of (32)P into phospholipids of freshwater eels by Zwingelstein, G, Brichon, G, Abdul Malak, N, Bodennec, J, Portoukalian, J

“…The effects of L-thyroxine on phospholipid biosynthesis, via (32)P incorporation, were studied in gill, kidney, liver and muscle tissue of eels acclimatized at…”
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Subcellular compartmentalization of ceramide metabolism: MAM (mitochondria-associated membrane) and/or mitochondria? by Bionda, Clara, Portoukalian, Jacques, Schmitt, Daniel, Rodriguez-Lafrasse, Claire, Ardail, Dominique

“…Recent studies by our group and others have disclosed the presence of ceramides in mitochondria, and the activities of ceramide synthase and reverse ceramidase…”
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Analysis of glycosphingolipids of human head and neck carcinomas with comparison to normal tissue by Bolot, G., David, M. J., Taki, T., Handa, S., Kasama, T., Richard, M., Pignat, J. C., Thomas, L., Portoukalian, J.

“…Glycosphingolipids of head and neck carcinomas from six tumor‐bearing patients were analyzed and compared to those of normal tissue from similar areas. The…”
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Induction of IgG antibodies directed to a M(r) 31,000 melanoma antigen in patients immunized with vaccinia virus melanoma oncolysates by Berthier-Vergnes, O, Portoukalian, J, Lefthériotis, E, Doré, J F

“…Pre- and postimmunization sera from eight tumor-free melanoma patients undergoing vaccinia melanoma oncolysate (VMO) therapy were used to investigate the…”
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