Search Results - "PORTILLA, Federico del RIO"
-
1
Successful refolding and NMR structure of rMagi3: A disulfide‐rich insecticidal spider toxin
Published in Protein science (01-03-2018)“…The need for molecules with high specificity against noxious insects leads the search towards spider venoms that have evolved highly selective toxins for…”
Get full text
Journal Article -
2
Decoding the mechanism governing the structural stability of wheat germ agglutinin and its isolated domains: A combined calorimetric, NMR, and MD simulation study
Published in Protein science (01-06-2024)“…Wheat germ agglutinin (WGA) demonstrates potential as an oral delivery agent owing to its selective binding to carbohydrates and its capacity to traverse…”
Get full text
Journal Article -
3
Bacterial expression, purification and biophysical characterization of wheat germ agglutinin and its four hevein‐like domains
Published in Biopolymers (01-01-2019)“…Wheat germ agglutinin (WGA), a chitin binding lectin, has attracted increasing interest because of its unique characteristics such as conformational stability,…”
Get full text
Journal Article -
4
Novel Blocker of Onco SK3 Channels Derived from Scorpion Toxin Tamapin and Active against Migration of Cancer Cells
Published in ACS medicinal chemistry letters (13-08-2020)“…Peptide-based therapy against cancer is a field of great interest for biomedical developments. Since it was shown that SK3 channels promote cancer cell…”
Get full text
Journal Article -
5
Structure, Function, and Chemical Synthesis of Vaejovis mexicanus Peptide 24: A Novel Potent Blocker of Kv1.3 Potassium Channels of Human T Lymphocytes
Published in Biochemistry (Easton) (15-05-2012)“…Animal venoms are rich sources of ligands for studying ion channels and other pharmacological targets. Proteomic analyses of the soluble venom from the Mexican…”
Get full text
Journal Article -
6
Resin glycosides from Ipomoea tyrianthina and their sedative and vasorelaxant effects
Published in Journal of natural medicines (01-10-2014)“…The methanol-soluble extract from the root of Ipomoea tyrianthina was studied in order to isolate compounds with activity on the central nervous system and…”
Get full text
Journal Article -
7
Structural and functional studies of scorpine: A channel blocker and cytolytic peptide
Published in Toxicon (Oxford) (15-01-2023)“…Scorpine is an antimicrobial and antimalarial peptide isolated from Pandinus imperator scorpion venom. As there are few functional and structural studies…”
Get full text
Journal Article -
8
Cytotoxicity of Recombinant Tamapin and Related Toxin-Like Peptides on Model Cell Lines
Published in Chemical research in toxicology (16-06-2014)“…The scorpion toxin tamapin displays the most potent and selective blockage against KCa2.2 channels known to date. In this work, we report the biosynthesis,…”
Get full text
Journal Article -
9
Encapsulation Enhances the Catalytic Activity of C‐N Coupling: Reaction Mechanism of a Cu(I)/Calix[8]arene Supramolecular Catalyst
Published in ChemCatChem (21-10-2022)“…Development of C−N coupling methodologies based on Earth‐abundant metals is a promising strategy in homogeneous catalysis for sustainable processes. However,…”
Get full text
Journal Article -
10
Solution NMR structure of cementum protein 1 derived peptide (CEMP1-p1) and its role in the mineralization process
Published in Journal of peptide science (01-10-2023)“…We report the characterization of the three-dimensional structure of the CEMP1-p1 peptide [MGTSSTDSQQAQHRRCSTSN: corresponding to residues 1-20 of the…”
Get full text
Journal Article -
11
Changes in quality and quantity of soil organic matter stocks resulting from wastewater irrigation in formerly forested land
Published in Geoderma (15-11-2017)“…Land use changes often diminish soil carbon stocks and alter soil organic matter (SOM) quality affecting soil productivity. Therefore, intensively managed…”
Get full text
Journal Article -
12
Solution structure and antiparasitic activity of scorpine‐like peptides from Hoffmannihadrurus gertschi
Published in FEBS letters (01-07-2016)“…Scorpine‐like peptides are two domain peptides found in different scorpion venoms displaying various antimicrobial, cytolytic, and potassium channel‐blocking…”
Get full text
Journal Article -
13
Insights on Structure and Function of a Late Embryogenesis Abundant Protein from Amaranthus cruentus : An Intrinsically Disordered Protein Involved in Protection against Desiccation, Oxidant Conditions, and Osmotic Stress
Published in Frontiers in plant science (07-04-2017)“…Late embryogenesis abundant (LEA) proteins are part of a large protein family that protect other proteins from aggregation due to desiccation or osmotic…”
Get full text
Journal Article -
14
New tricks of an old pattern: structural versatility of scorpion toxins with common cysteine spacing
Published in The Journal of biological chemistry (06-04-2012)“…Scorpion venoms are a rich source of K(+) channel-blocking peptides. For the most part, they are structurally related small disulfide-rich proteins containing…”
Get full text
Journal Article -
15
Nucleophilic Reactions on 1-Trifluoromethanesulfonylpyridinium Trifluoromethanesulfonate (Triflypyridinium Triflate, TPT).Ring-Opening and "Unexpected" 1, 4-Dihydropyridine Reaction Products
Published in Chemical & pharmaceutical bulletin (1997)“…The reaction products of 1-trifluoromethanesulfonylpyridinium trifluoromethanesulfonate (TPT) with secondary amines have been thoroughly examined by…”
Get full text
Journal Article -
16
Cyclopurpuracin, a cyclopeptide from Annona purpurea seeds
Published in Phytochemistry letters (01-02-2018)Get full text
Journal Article -
17
Hepta‐, hexa‐, penta‐, tetra‐, and trisaccharide resin glycosides from three species of Ipomoea and their antiproliferative activity on two glioma cell lines
Published in Magnetic resonance in chemistry (01-03-2017)“…Six new partially acylated resin glycosides were isolated from convolvulin of Ipomoea purga, Ipomoea stans, and Ipomoea murucoides (Convolvulaceae). The…”
Get full text
Journal Article -
18
Fluorescence, circular dichroism, NMR, and docking studies of the interaction of the alkaloid malbrancheamide with calmodulin
Published in Journal of enzyme inhibition and medicinal chemistry (01-06-2011)“…A new malbrancheamide analogue, isomalbrancheamide B (3), along with three known compounds, malbrancheamide (1), isomalbrancheamide (2), and premalbrancheamide…”
Get more information
Journal Article -
19
Synthesis and full characterization of tert-butyl (4-ethynylphenyl)carbamate
Published in Journal of molecular structure (05-02-2025)“…•High yield synthesis of tert-butyl (4-ethynylphenyl)carbamate.•Complete characterization by NMR, FTIR, HRMS and UV–vis.•Unequivocal assignment of 1H and 13C…”
Get full text
Journal Article -
20
The three-dimensional structure of the toxic peptide Cl13 from the scorpion Centruroides limpidus
Published in Toxicon (Oxford) (01-09-2020)“…Cl13 is a toxin purified previously from the venom of the Mexican scorpion Centruroides limpidus. This toxin affects the function of voltage gated…”
Get full text
Journal Article