Search Results - "PORRO, STEFANIA"
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Reduced SIRT1 and SIRT2 expression promotes adipogenesis of human visceral adipose stem cells and associates with accumulation of visceral fat in human obesity
Published in International Journal of Obesity (01-02-2020)“…Background/Objectives The histone deacetylases SIRT1 and SIRT2 have been shown to be involved in the differentiation of rodent adipocyte precursors. In light…”
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1762-P: Insulin Receptor Isoforms in Human Adipose Tissue and Adipose Stem Cells
Published in Diabetes (New York, N.Y.) (01-06-2019)“…Insulin regulates the development and metabolism of adipose tissue (AT) by activating its tyrosine kinase receptor in this tissue. The insulin receptor (IR)…”
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1763-P: The Secretome from Visceral Adipose Stem Cells of Obese Subjects Induces Apoptosis and Insulin Resistance in Cardiac Progenitor Cells
Published in Diabetes (New York, N.Y.) (01-06-2019)“…Increased abdominal visceral adipose tissue (VAT) is associated with cardiovascular risk in metabolically unhealthy subjects. The viability of cardiac…”
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1134-P: The Secretome of Visceral Adipose Cells Induces Apoptosis of Cardiac Progenitor Cells in Human Obesity: Protective Effects of the SGLT2 Inhibitor Dapagliflozin
Published in Diabetes (New York, N.Y.) (01-06-2020)“…This study aimed to assess whether the secretome from abdominal visceral (AV) and epicardial (E) adipose stem cells (ASC), ASC-derived mature adipocytes, and…”
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Correction of intermittent hypoxia reduces inflammation in obese subjects with obstructive sleep apnea
Published in JCI insight (07-09-2017)“…In obese subjects with obstructive sleep apnea (OSA), chronic intermittent hypoxia (CIH) may be linked to systemic and adipose tissue inflammation. We obtained…”
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The p66Shc protein controls redox signaling and oxidation-dependent DNA damage in human liver cells
Published in American journal of physiology: Gastrointestinal and liver physiology (15-11-2015)“…The p66Shc protein mediates oxidative stress-related injury in multiple tissues. Steatohepatitis is characterized by enhanced oxidative stress-mediated cell…”
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