Search Results - "POROLA, P"

Activation of plasmacytoid dendritic cells by apoptotic particles – mechanism for the loss of immunological tolerance in Sjögren's syndrome by Ainola, M., Porola, P., Takakubo, Y., Przybyla, B., Kouri, V. P., Tolvanen, T. A., Hänninen, A., Nordström, D. C.

“…Summary Sjögren's syndrome (SS) is a common autoimmune disease targeting salivary and lacrimal glands. It is strongly female‐dominant, characterized by low…”
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Sjögren’s syndome and extragonadal sex steroid formation: A clue to a better disease control? by Konttinen, Y.T., Stegajev, V., Al-Samadi, A., Porola, P., Hietanen, J., Ainola, M.

“…•Salivary gland epithelial cells produce by and for themselves DHT using intracrine enzymes.•Menopause increases the need for intracrine DHEA-DHT conversion in…”
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Brief Report: First identification of H4 histamine receptor in healthy salivary glands and in focal sialadenitis in Sjögren's syndrome by Stegaev, V., Sillat, T., Porola, P., Hänninen, A., Falus, A., Mieliauskaite, D., Buzás, E., Rotar, Z., Mackiewicz, Z., Stark, H., Chazot, P. L., Konttinen, Y. T.

“…Objective The conventional H1 and H2 histamine receptors have >10,000‐fold lower avidity for histamine than H4 histamine receptor, which has been implicated in…”
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Histamine transport and metabolism are deranged in salivary glands in Sjogren's syndrome by Stegaev, Vasily, Nies, Anne T, Porola, Pauliina, Mieliauskaite, Diana, Sánchez-Jiménez, Francisca, Urdiales, Jóse L, Sillat, Tarvo, Schwelberger, Hubert G, Chazot, Paul L, Katebe, Mwape, Mackiewicz, Zygmunt, Konttinen, Yrjö T, Nordström, Dan C E

“…To study histamine transport and metabolism of salivary gland (SG) epithelial cells in healthy controls and SS patients. Enzymes and transporters involved in…”
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Salivary glands - `an unisex organ'? by Konttinen, YT, Stegaev, V, Mackiewicz, Z, Porola, P, Hänninen, A, Szodoray, P

“…Oral Diseases (2010) 16, 577–585 Usually no distinction is made between female and male salivary glands although cyclic changes of and/or differences in serum…”
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Failure of oral DHEA treatment to increase local salivary androgen outputs of female patients with Sjögren's syndrome by Porola, P, Straub, RH, Virkki, LM, Konttinen, YT, Nordström, DC

“…Objectives: Sjögren's syndrome (SS) is a female-dominant autoimmune disease characterized by androgen depletion and defective dehydroepiandrosterone (DHEA)…”
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Acinar epithelial cell laminin-receptors in labial salivary glands in Sjogren's syndrome by LAINE, M, VIRTANEN, I, POROLA, P, ROTAR, Z, ROZMAN, B, PODUVAL, P, KONTTINEN, Y. T

“…To analyze the epithelial cell-basement membrane attachment, in particular in the secretory end pieces (responsible for secretion of saliva) and in Sjögren's…”
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Activation of plasmacytoid dendritic cells by apoptotic particlesￂ -ￂ mechanism for the loss of immunological tolerance in Sjögren's syndrome by Ainola, M, Porola, P, Takakubo, Y, Przybyla, B, Kouri, V P, Tolvanen, T A, Hanninen, A, Nordstrom, D C

“…Summary Sjögren's syndrome (SS) is a common autoimmune disease targeting salivary and lacrimal glands. It is strongly female-dominant, characterized by low…”
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Abnormal basement membrane type IV collagen α‐chain composition in labial salivary glands in Sjögren's syndrome by Poduval, P., Sillat, T., Virtanen, I., Porola, P., Konttinen, Y. T.

“…Objective Sjögren's syndrome (SS) is characterized by atrophy and malfunction of the acinar cells. The aim of this study was to investigate whether type IV…”
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Abnormal distribution of aquaporin-5 in salivary glands in the NOD mouse model for Sjögren's syndrome by KONTTINEN, Yrjö T, TENSING, Eve-Kai, LAINE, Mikael, POROLA, Pauliina, TÖRNWALL, Jyrki, HUKKANEN, Mika

“…To localize aquaporin-5 in healthy salivary gland acinar cells and to check if it is abnormally translocated in an experimental NOD mouse model for Sjögren's…”
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Exosomal secretion of death bullets: a new way of apoptotic escape? by Trokovic, Nina, Pöllänen, Raimo, Porola, Pauliina, Stegaev, Vasily, Hetzel, Udo, Tivesten, Åsa, Engdahl, Cecilia, Carlsten, Hans, Forsblad-d'Elia, Helena, Fagman, Johan Bourghardt, Lagerquist, Marie, Konttinen, Yrjö T

“…Ovariectomy/estrogen deficiency causes selective apoptosis of the serous epithelial cells of the submandibular glands (SMG) in female mice. Because such…”
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Brief Report: First identification of H 4 histamine receptor in healthy salivary glands and in focal sialadenitis in Sjögren's syndrome by Stegaev, V., Sillat, T., Porola, P., Hänninen, A., Falus, A., Mieliauskaite, D., Buzás, E., Rotar, Z., Mackiewicz, Z., Stark, H., Chazot, P. L., Konttinen, Y. T.

“…Abstract Objective The conventional H 1 and H 2 histamine receptors have >10,000‐fold lower avidity for histamine than H 4 histamine receptor, which has been…”
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First Identification of H4 Histamine Receptor in Healthy Salivary Glands and in Focal Sialadenitis in Sjögren's Syndrome by STEGAEV, V, SILLAT, T, CHAZOT, P. L, KONTTINEN, Y. T, POROLA, P, HÄNNINEN, A, FALUS, A, MIELIAUSKAITE, D, BUZAS, E, ROTAR, Z, MACKIEWICZ, Z, STARK, H

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Low salivary dehydroepiandrosterone and androgen‐regulated cysteine‐rich secretory protein 3 levels in Sjögren's syndrome by Laine, Mikael, Porola, Pauliina, Udby, Lene, Kjeldsen, Lars, Cowland, Jack B., Borregaard, Niels, Hietanen, Jarkko, Ståhle, Mona, Pihakari, Antti, Konttinen, Yrjö T.

“…Objective Sjögren's syndrome (SS), an autoimmune disease of exocrine glands, typically starts at the time of adrenopause. We undertook this study to test the…”
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