Search Results - "POPOVIC, ZORAN"
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Multistage nanoparticle delivery system for deep penetration into tumor tissue
Published in Proceedings of the National Academy of Sciences - PNAS (08-02-2011)“…Current Food and Drug Administration-approved cancer nanotherapeutics, which passively accumulate around leaky regions of the tumor vasculature because of an…”
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2
Power to the People: Addressing Big Data Challenges in Neuroscience by Creating a New Cadre of Citizen Neuroscientists
Published in Neuron (Cambridge, Mass.) (02-11-2016)“…Global neuroscience projects are producing big data at an unprecedented rate that informatic and artificial intelligence (AI) analytics simply cannot handle…”
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Prognostic Value of Global Longitudinal Strain in Hypertrophic Cardiomyopathy: A Systematic Review of Existing Literature
Published in JACC. Cardiovascular imaging (01-10-2019)“…The association of left ventricular global longitudinal strain (LV-GLS) with clinical outcomes in patients with hypertrophic cardiomyopathy (HCM) has been…”
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4
Predicting protein structures with a multiplayer online game
Published in Nature (05-08-2010)“…People exert large amounts of problem-solving effort playing computer games. Simple image- and text-recognition tasks have been successfully 'crowd-sourced'…”
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5
Cancer Acidity and Hypertonicity Contribute to Dysfunction of Tumor-Associated Dendritic Cells: Potential Impact on Antigen Cross-Presentation Machinery
Published in Cancers (01-09-2020)“…Macrophages (MΦ) and dendritic cells (DC), major players of the mononuclear phagocyte system (MoPh), are potent antigen presenting cells that steadily sense…”
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6
Crystal structure of a monomeric retroviral protease solved by protein folding game players
Published in Nature structural & molecular biology (01-10-2011)“…Following the failure of a wide range of attempts to solve the crystal structure of M-PMV retroviral protease by molecular replacement, we challenged players…”
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7
Structural consequences of arrested foveal development in preterms with persisting signs of immaturity
Published in Eye (London) (01-06-2020)“…Purpose To evaluate the impact of structural changes in a limited sample of adult preterms with foveal immaturity from optical coherence tomography (OCT)…”
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8
Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels
Published in Nature communications (01-10-2013)“…Cancer and stromal cells actively exert physical forces (solid stress) to compress tumour blood vessels, thus reducing vascular perfusion. Tumour interstitial…”
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9
Late Gadolinium Enhancement in Patients With Hypertrophic Cardiomyopathy and Preserved Systolic Function
Published in Journal of the American College of Cardiology (21-08-2018)“…A high proportion of patients with hypertrophic cardiomyopathy (HCM) have evidence of late gadolinium enhancement (LGE) on cardiac magnetic resonance (CMR)…”
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10
Normalization of tumour blood vessels improves the delivery of nanomedicines in a size-dependent manner
Published in Nature nanotechnology (08-04-2012)“…The blood vessels of cancerous tumours are leaky 1 , 2 , 3 and poorly organized 4 , 5 , 6 , 7 . This can increase the interstitial fluid pressure inside…”
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11
Assessment of glomerular morphological patterns by deep learning algorithms
Published in Journal of nephrology (01-03-2022)“…Background Compilation of different morphological lesion signatures is characteristic of renal pathology. Previous studies have documented the potential value…”
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A comprehensive molecular characterization of the 8q22.2 region reveals the prognostic relevance of OSR2 mRNA in muscle invasive bladder cancer
Published in PloS one (12-03-2021)“…Technological advances in molecular profiling have enabled the comprehensive identification of common regions of gene amplification on chromosomes (amplicons)…”
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13
Deep learning can predict survival directly from histology in clear cell renal cell carcinoma
Published in PloS one (17-08-2022)“…For clear cell renal cell carcinoma (ccRCC) risk-dependent diagnostic and therapeutic algorithms are routinely implemented in clinical practice. Artificial…”
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14
Prognostic implication of relative regional strain ratio in cardiac amyloidosis
Published in Heart (British Cardiac Society) (01-05-2016)“…Cardiac amyloidosis (CA) is a rapidly progressive disease that portends poor prognosis. Our objective was to evaluate the prognostic impact of relative…”
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Incremental Prognostic Utility of Left Ventricular Global Longitudinal Strain in Asymptomatic Patients With Significant Chronic Aortic Regurgitation and Preserved Left Ventricular Ejection Fraction
Published in JACC. Cardiovascular imaging (01-05-2018)“…Abstract Objectives We sought to examine the prognostic utility of left ventricular (LV) global longitudinal strain (GLS) in asymptomatic patients with ≥III+…”
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16
De novo protein design by citizen scientists
Published in Nature (London) (01-06-2019)“…Online citizen science projects such as GalaxyZoo 1 , Eyewire 2 and Phylo 3 have proven very successful for data collection, annotation and processing, but for…”
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Diastolic Stress Echocardiography in Patients With Hypertrophy Cardiomyopathy: Association With Exercise Capacity
Published in The American journal of cardiology (01-12-2024)“…Diastolic dysfunction plays a major role in precipitating congestive heart failure in patients with hypertrophic cardiomyopathy (HCM). In many such patients,…”
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Post-COVID-19 complement-mediated TMA: A case report
Published in Clinical nephrology (01-10-2024)“…Systemic COVID-19 disease is associated with a variety of organ involvement in infected patients. A rarely reported complication is the induction of…”
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Survival After Septal Reduction in Patients >65 Years Old With Obstructive Hypertrophic Cardiomyopathy
Published in Journal of the American College of Cardiology (17-01-2023)“…Obstructive hypertrophic cardiomyopathy (oHCM) is increasingly being diagnosed in elderly patients. The authors sought to study long-term outcomes of septal…”
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20
Short-Range Order in VI3
Published in Inorganic chemistry (16-11-2020)“…We present a detailed investigation of the crystal structure of VI3, a two-dimensional van der Waals material of interest for studies of low-dimensional…”
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