Search Results - "POPA WAGNER, Aurel"
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The post‐stroke young adult brain has limited capacity to re‐express the gene expression patterns seen during early postnatal brain development
Published in Brain pathology (Zurich, Switzerland) (01-09-2024)“…The developmental origins of the brain's response to injury can play an important role in recovery after a brain lesion. In this study, we investigated whether…”
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Post‐stroke depression: mechanisms, translation and therapy
Published in Journal of cellular and molecular medicine (01-09-2012)“…The interaction between depression and stroke is highly complex. Post‐stroke depression (PSD) is among the most frequent neuropsychiatric consequences of…”
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Caloric restriction stabilizes body weight and accelerates behavioral recovery in aged rats after focal ischemia
Published in Aging cell (01-12-2017)“…Summary Obesity and hyperinsulinemia are risk factors for stroke. We tested the hypothesis that caloric restriction, which reduces the incidence of age‐related…”
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Medication‐related osteonecrosis of the jaw: A disease of significant importance for older patients
Published in Journal of the American Geriatrics Society (JAGS) (01-08-2023)“…Background Medication‐related osteonecrosis of the jaw (MRONJ) is clinically defined as a non‐healing jawbone ulcerative‐necrotic lesion appearing after dental…”
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Microglial morphology in the somatosensory cortex across lifespan. A quantitative study
Published in Developmental dynamics (01-08-2023)“…Background Microglia are long‐lived cells that constantly monitor their microenvironment. To accomplish this task, they constantly change their morphology both…”
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Editorial: Advances and challenges in stroke therapy: A regenerative prospective
Published in Frontiers in neuroscience (12-12-2022)Get full text
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Potassium Channels Kv1.3 and Kir2.1 But Not Kv1.5 Contribute to BV2 Cell Line and Primary Microglial Migration
Published in International journal of molecular sciences (19-02-2021)“…(1) Background: As membrane channels contribute to different cell functions, understanding the underlying mechanisms becomes extremely important. A large…”
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Neuroinflammation and comorbidities are frequently ignored factors in CNS pathology
Published in Neural regeneration research (01-09-2015)“…Virtually all drug interventions that have been successful pre-clinically in experimental stroke have failed to prove their efficacy in a dinical setting. This…”
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Dynamic Brain Lipid Profiles Modulate Microglial Lipid Droplet Accumulation and Inflammation Under Ischemic Conditions in Mice
Published in Advanced science (01-11-2024)“…Microglia are critically involved in post‐stroke inflammation affecting neurological outcomes. Lipid droplet (LD) accumulation in microglia results in a…”
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The Treatment of Severe Periodontitis Using a Local Antiseptic Desiccant and Subgingival Mechanical Instrumentation: A Pilot Study
Published in Journal of clinical medicine (26-06-2023)“…This randomized, split-mouth, controlled clinical study assessed the additional clinical benefits of a local desiccant antimicrobial agent (HY) combined with…”
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Oral Mesenchymal Stromal Cells in Systemic Sclerosis: Characterization and Response to a Hyaluronic-Acid-Based Biomaterial
Published in Applied sciences (01-09-2021)“…Introduction. As oral mesenchymal stromal cells (MSCs) have not, to date, been isolated from systemic sclerosis (SSc) patients, the aim of this in vitro…”
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ROS and Brain Diseases : The Good, the Bad, and the Ugly
Published in Oxidative medicine and cellular longevity (01-01-2013)“…The brain is a major metabolizer of oxygen and yet has relatively feeble protective antioxidant mechanisms. This paper reviews the Janus-faced properties of…”
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Multicellular Crosstalk Between Exosomes and the Neurovascular Unit After Cerebral Ischemia. Therapeutic Implications
Published in Frontiers in neuroscience (06-11-2018)“…Restorative strategies after stroke are focused on the remodeling of cerebral endothelial cells and brain parenchymal cells. The latter, i.e., neurons, neural…”
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Ageing and comorbidities in humans with antigliadin antibodies
Published in Journal of gastrointestinal and liver diseases : JGLD (16-09-2022)Get full text
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Proteomic identification of an upregulated isoform of annexin A3 in the rat brain following reversible cerebral ischemia
Published in Glia (01-12-2007)“…We used proteomics to identify regulated proteins following cerebral ischemia in a rat model. Young rats were subjected to reversible middle cerebral artery…”
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Identification of transcriptome alterations in the prefrontal cortex, hippocampus, amygdala and hippocampus of suicide victims
Published in Scientific reports (22-09-2021)“…Suicide is one of the leading causes of death globally for all ages, and as such presents a very serious problem for clinicians worldwide. However, the…”
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Beam narrowing test: a motor index of post-stroke motor evaluation in an aged rat model of cerebral ischemia
Published in Journal of Neural Transmission (01-07-2024)“…Each year, 15 million people worldwide suffer from strokes. Consequently, researchers face increasing pressure to develop reliable behavioural tests for…”
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Monomeric C-Reactive Protein and Cerebral Hemorrhage: From Bench to Bedside
Published in Frontiers in immunology (11-09-2018)“…C-reactive protein (CRP) is an important mediator and a hallmark of the acute-phase response to inflammation. High-sensitivity assays that accurately measure…”
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Dietary habits, lifestyle factors and neurodegenerative diseases
Published in Neural regeneration research (01-03-2020)“…Worldwide stroke is increasing in parallel with modernization, changes in lifestyle, and the growing elderly population. Our review is focused on the link…”
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Translatability of life‐extending pharmacological treatments between different species
Published in Aging cell (01-07-2024)“…Anti‐aging research has made significant strides in identifying treatments capable of extending lifespan across a range of organisms, from simple invertebrates…”
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