Search Results - "POON, Donald"

Multicenter phase II study of sequential radioembolization-sorafenib therapy for inoperable hepatocellular carcinoma by Chow, Pierce K H, Poon, Donald Y H, Khin, Maung-Win, Singh, Harjit, Han, Ho-Seong, Goh, Anthony S W, Choo, Su-Pin, Lai, Hee-Kit, Lo, Richard H G, Tay, Kiang-Hiong, Lim, Teong-Guan, Gandhi, Mihir, Tan, Say-Beng, Soo, Khee-Chee

“…The safety and tolerability of sequential radioembolization-sorafenib therapy is unknown. An open-label, single arm, investigator-initiated Phase II study…”
Get full text

Analysis of Prognostic Factors of Comprehensive Geriatric Assessment and Development of a Clinical Scoring System in Elderly Asian Patients With Cancer by KANESVARAN, Ravindran, HUIHUA LI, KOO, Khai-Nee, POON, Donald

“…To determine the impact of each comprehensive geriatric assessment (CGA) domain on overall survival (OS) and develop a prognostic scoring system for elderly…”
Get full text

Management of hepatocellular carcinoma in Asia: consensus statement from the Asian Oncology Summit 2009 by Poon, Donald, Dr, Anderson, Benjamin O, Prof, Chen, Li-Tzong, MD, Tanaka, Koichi, Prof, Lau, Wan Yee, Prof, Van Cutsem, Eric, Prof, Singh, Harjit, MD, Chow, Wan Cheng, Prof, Ooi, London Lucien, Prof, Chow, Pierce, MD, Khin, Maung Win, Prof, Koo, Wen Hsin, MD

“…Summary Asia has a disproportionately large share of the world's hepatocellular carcinoma (HCC), mainly because of the endemic status of chronic hepatitis B…”
Get full text

Dynamic contrast-enhanced CT imaging of hepatocellular carcinoma in cirrhosis: feasibility of a prolonged dual-phase imaging protocol with tracer kinetics modeling by Koh, Tong San, Thng, Choon Hua, Hartono, Septian, Lee, Puor Sherng, Choo, Su Pin, Poon, Donald Y. H., Toh, Han Chong, Bisdas, Sotirios

“…Dynamic contrast-enhanced (DCE) CT imaging of four patients with hepatocellular carcinoma (HCC) was performed using a dual-phase imaging protocol designed with…”
Get full text

Identification of Comprehensive Geriatric Assessment Based Risk Factors for Malnutrition in Elderly Asian Cancer Patients by Tan, Tira, Ong, Whee Sze, Rajasekaran, Tanujaa, Nee Koo, Khai, Chan, Li Li, Poon, Donald, Roy Chowdhury, Anupama, Krishna, Lalit, Kanesvaran, Ravindran

“…Elderly cancer patients are at increased risk for malnutrition. We aim to identify comprehensive geriatric assessment (CGA) based clinical factors associated…”
Get full text

Sorafenib and rapamycin induce growth suppression in mouse models of hepatocellular carcinoma by Huynh, Hung, Ngo, Van Chanh, Koong, Heng Nung, Poon, Donald, Choo, Su Pin, Thng, Choon Hua, Chow, Pierce, Ong, Hock Soo, Chung, Alexander, Soo, Khee Chee

“…Hepatocellular carcinoma (HCC) is the fifth most common malignancy worldwide. Vascular endothelial growth factor, platelet derived growth factor and the…”
Get full text

AZD6244 enhances the anti-tumor activity of sorafenib in ectopic and orthotopic models of human hepatocellular carcinoma (HCC) by Huynh, Hung, Ngo, Van Chanh, Koong, Heng Nung, Poon, Donald, Choo, Su Pin, Toh, Han Chong, Thng, Choon Hua, Chow, Pierce, Ong, Hock Soo, Chung, Alexander, Goh, Boon Cher, Smith, Paul D, Soo, Khee Chee

“…Background & Aims Hepatocellular carcinoma (HCC) is a particularly vascularized solid tumor where the Raf/MEK/ERK pathway is activated; suggesting that…”
Get full text

Activity of thalidomide and capecitabine in patients with advanced hepatocellular carcinoma by Ang, Soo-Fan, Tan, Sze-Huey, Toh, Han-Chong, Poon, Donald Y H, Ong, Simon Y K, Foo, Kian-Fong, Choo, Su-Pin

“…Thalidomide has shown modest activity in advanced hepatocellular carcinomas (HCCs). Single-agent capecitabine has also been used in patients with HCC, with…”
Get full text

Phase II trial of gemcitabine in combination with cisplatin in inoperable or advanced hepatocellular carcinoma by Chia, Whay Kuang, Ong, Simon, Toh, Han Chong, Hee, Siew Wan, Choo, Su Pin, Poon, Donald Y H, Tay, Miah Hiang, Tan, Chee Kiat, Koo, Wen Hsin, Foo, Kian Fong

“…Advanced hepatocellular carcinoma (HCC) has a dismal prognosis and is notoriously chemo-resistant. We conducted a Phase II prospective study to evaluate the…”
Get more information

Gastrointestinal stromal tumour in the elderly by Tham, Chee-Kian, Poon, Donald Yew-Hee, Li, Hui-Hua, Tan, Min-Han, Choo, Su-Pin, Foo, Kian-Fong

“…Abstract Aim To analyze the outcome of elderly patients compared with the younger age group patients who were diagnosed with gastrointestinal stromal tumours…”
Get full text

Stage 4 pancreatic adenocarcinoma harbouring an FGFR2-TACC2 fusion mutation with complete response to erdafitinib a pan-fibroblastic growth factor receptor inhibitor by Poon, Donald, Tan, Min Han, Khor, Damian

“…We report a case of a frail 68-year-old woman with stage 4 pancreatic carcinoma harbouring a fibroblastic growth factor receptor 2 (FGFR2) fusion who achieved…”
Get full text

Phase III study of pasireotide long-acting release in patients with metastatic neuroendocrine tumors and carcinoid symptoms refractory to available somatostatin analogues by Wolin, Edward M, Jarzab, Barbara, Eriksson, Barbro, Walter, Thomas, Toumpanakis, Christos, Morse, Michael A, Tomassetti, Paola, Weber, Matthias M, Fogelman, David R, Ramage, John, Poon, Donald, Gadbaw, Brian, Li, Jiang, Pasieka, Janice L, Mahamat, Abakar, Swahn, Fredrik, Newell-Price, John, Mansoor, Wasat, Öberg, Kjell

“…In a randomized, double-blind, Phase III study, we compared pasireotide long-acting release (pasireotide LAR) with octreotide long-acting repeatable…”
Get full text

Molecular and Other Novel Advances in Treatment of Metastatic Epithelial and Medullary Thyroid Cancers by Tai, David, Poon, Donald

“…An understanding of the mutations of the proto-oncogenes and tumor suppressor genes that occur in thyroid cancers should eventually explain the diverse…”
Get full text

RAD001 (everolimus) inhibits tumour growth in xenograft models of human hepatocellular carcinoma by Huynh, Hung, Pierce Chow, K.H., Soo, Khee Chee, Toh, Han Chong, Choo, Su Pin, Foo, Kian Fong, Poon, Donald, Ngo, Van Chanh, Tran, Evelyn

“…Hepatocellular carcinoma (HCC) is the fifth most common malignancy worldwide and highly resistant to available chemotherapies. Mammalian target of rapamycin…”
Get full text

Abstract 6399: Real-world experience of an Asian pan-cancer combined DNA/RNA next generation sequencing (NGS) tissue biopsy assay by Chan, Jason Yongsheng, Lee, Jing Yi, Wan, Zi Yi, Lim, Abner Herbert, Ko, Tun Kiat, Ng, Cedric Chuan-Young, Poon, Donald, Samol, Jens, So, Tsz Him, Choo, Su Pin, Kanesvaran, Ravindran, Hui, Cheng-Vai, Au, Joseph Siu-Kie, Helali, Aya El, Yip, Timothy, Rajasegaran, Vikneswari, Lim, Sandy, Weng, Ruifen, Tan, Puay Hoon, Teh, Bin Tean, Tan, Min-Han, Poh, Jonathan

“…Abstract Introduction: Comprehensive molecular profiling with combined DNA-RNA next-generation sequencing (NGS) on tumor tissue is now increasingly being used…”
Get full text

Comprehensive Geriatric Assessment (CGA) based risk factors for increased caregiver burden among elderly Asian patients with cancer by Rajasekaran, Tanujaa, Tan, Tira, Ong, Whee Sze, Koo, Khai Nee, Chan, Lili, Poon, Donald, Roy Chowdhury, Anupama, Krishna, Lalit, Kanesvaran, Ravindran

“…Abstract Objective This study aims to identify Comprehensive Geriatric Assessment (CGA) based risk factors to help predict caregiver burden among elderly…”
Get full text

Identification of comprehensive geriatric assessment based risk factors for malnutrition in elderly Asian patients with cancer by Tan, Tira Jing Ying, Ong, Whee Sze, Koo, Khai-Nee, Tan, Iain B., Poon, Donald, Kanesvaran, Ravindran

“…Abstract only 9552 Background: Elderly patients with cancer are at increased risk for poor nutrition. Malnutrition is associated with increased morbidity and…”
Get full text

The Influence of Primary Site on Outcomes in Leiomyosarcoma: A Review of Clinicopathologic Differences Between Uterine and Extrauterine Disease by FARID, Mohamad, WHEE SZE ONG, JEEVAN, Raaj, CHIN, Francis, TEO, Melissa, QUEK, Richard, MANN HONG TAN, LEON SIANG SHEN FOO, YONG KUEI LIM, WHAY KUANG CHIA, LAY TIN SOH, POON, Donald, JIN FU LEE, Marcus, ZHEN CHONG HO

“…Leiomyosarcomas (LMS) comprise 25% of soft tissue sarcomas. Recent reports suggest differences in treatment outcomes between uterine (uLMS) and extrauterine…”
Get full text

Triplet combination of gemcitabine, paclitaxel, and carboplatin followed by maintenance 5‐fluorouracil and folinic acid in patients with metastatic nasopharyngeal carcinoma by Leong, Swan Swan, Wee, Joseph, Rajan, Sandeep, Toh, Chee Keong, Lim, Wan Teck, Hee, Siew Wan, Tay, Miah Hiang, Poon, Donald, Tan, Eng Huat

“…BACKGROUND. Nasopharyngeal carcinoma (NPC) is a disease that is highly responsive to various chemotherapeutic agents. In the metastatic setting, 2‐drug…”
Get full text

Quality of life of elderly patients undergoing concomitant chemoradiation therapy for head and neck cancers, including assessment of geriatric parameters by Extermann, Martine, Fulp, William J, Lee, Ji-Hyun, Kish, Julie Ann, Sehovic, Marina, Poon, Donald, Gwede, Clement

“…Abstract only 6100 Background: Data on the quality of life of older patients undergoing concomitant chemoradiation therapy (CCRT) for head and neck (H&N)…”
Get full text