Search Results - "PONCHEL, F"

T cell subsets: an immunological biomarker to predict progression to clinical arthritis in ACPA-positive individuals by Hunt, L, Hensor, E M, Nam, J, Burska, A N, Parmar, R, Emery, P, Ponchel, F

“…Anticitrullinated protein antibody (ACPA)+ individuals with non-specific musculoskeletal symptoms are at risk of inflammatory arthritis (IA). This study aims…”
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Auto-antibodies to post-translationally modified proteins in osteoarthritis by Xie, X., van Delft, M.A.M., Shuweihdi, F., Kingsbury, S.R., Trouw, L.A., Doody, G.M., Conaghan, P.G., Ponchel, F.

“…Autoantibodies (AutoAbs) have been observed in osteoarthritis (OA) with broad antigenicity, although their prevalence and role remain unclear…”
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PLGA microspheres encapsulating siRNA anti-TNFalpha: Efficient RNAi-mediated treatment of arthritic joints by Présumey, J., Salzano, G., Courties, G., Shires, M., Ponchel, F., Jorgensen, C., Apparailly, F., De Rosa, G.

“…The aim of this study was to investigate potentialities of poly(dl-lactide–co-glycolide) (PLGA) microspheres for the delivery of small interfering RNAs…”
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Changes in peripheral blood immune cell composition in osteoarthritis by Ponchel, F, Burska, A.N, Hensor, E.M.A, Raja, R, Campbell, M, Emery, P, Conaghan, P.G

“…Summary Objectives Immune age-related abnormalities may synergise with osteoarthritis (OA) pathology. We explored whether abnormalities in the blood immune…”
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Interleukin-7 in rheumatoid arthritis by Churchman, S. M., Ponchel, F.

“…Recent data from several groups demonstrate high levels of IL-7 in the joints of RA patients, but much lower levels in OA. In contrast, circulating levels of…”
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Mesenchymal stem cells in rheumatoid synovium: enumeration and functional assessment in relation to synovial inflammation level by Jones, E, Churchman, S M, English, A, Buch, M H, Horner, E A, Burgoyne, C H, Reece, R, Kinsey, S, Emery, P, McGonagle, D, Ponchel, F

“…Achieving joint regeneration in rheumatoid arthritis (RA) represents a future challenge. Autologous synovial mesenchymal stem cells (MSCs) could be…”
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Differential CpG DNA methylation in peripheral naïve CD4 + T-cells in early rheumatoid arthritis patients by Pitaksalee, R, Burska, A N, Ajaib, S, Rogers, J, Parmar, R, Mydlova, K, Xie, X, Droop, A, Nijjar, J S, Chambers, P, Emery, P, Hodgett, R, McInnes, I B, Ponchel, F

“…The genetic risk associated with rheumatoid arthritis (RA) includes genes regulating DNA methylation, one of the hallmarks of epigenetic re-programing, as well…”
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Gene expression analysis in RA: towards personalized medicine by Burska, A N, Roget, K, Blits, M, Soto Gomez, L, van de Loo, F, Hazelwood, L D, Verweij, C L, Rowe, A, Goulielmos, G N, van Baarsen, L G M, Ponchel, F

“…Gene expression has recently been at the forefront of advance in personalized medicine, notably in the field of cancer and transplantation, providing a…”
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HLA-dependent autoantibodies against post-translationally modified collagen type II in type 1 diabetes mellitus by Strollo, R., Rizzo, P., Spoletini, M., Landy, R., Hughes, C., Ponchel, F., Napoli, N., Palermo, A., Buzzetti, R., Pozzilli, P., Nissim, A.

“…Aims/hypothesis In this study the involvement of oxidative stress in type 1 diabetes mellitus autoimmunity and the possible association with rheumatoid…”
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Towards understanding healthy ageing of bone marrow resident multipotential stromal cells by El-Jawhari, J, Ganguly, P, Burska, A, Ponchel, F, Giannoudis, P, Jones, E

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Determination of thymic function directly from peripheral blood: A validated modification to an established method by Lorenzi, A.R., Patterson, A.M., Pratt, A., Jefferson, M., Chapman, C.E., Ponchel, F., Isaacs, J.D.

“…The thymus contributes naïve, self MHC reactive, self tolerant T cells to the peripheral immune system throughout life, albeit with a log-linear decline with…”
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Multiplexing immunoassays for cytokine detection in the serum of patients with rheumatoid arthritis: lack of sensitivity and interference by rheumatoid factor by CHURCHMAN, S. M, GEILER, J, PARMAR, R, HORNER, E. A, CHURCH, L. D, EMERY, P, BUCH, M. H, MCDERMOTT, M. F, PONCHEL, F

“…Accurately measuring cytokines in clinical material remains an important challenge in the development of biomarkers. Enzyme-linked immunoabsorbent assays…”
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Abnormal T cell differentiation persists in patients with rheumatoid arthritis in clinical remission and predicts relapse by Burgoyne, C H, Field, S L, Brown, A K, Hensor, E M, English, A, Bingham, S L, Verburg, R, Fearon, U, Lawson, C A, Hamlin, P J, Straszynski, L, Veale, D, Conaghan, P, Hull, M A, van Laar, J M, Tennant, A, Emery, P, Isaacs, J D, Ponchel, F

“…An abnormal CD4+ T cell subset related to inflammation exposure (inflammation-related cells, IRC) has been identified in rheumatoid arthritis (RA). Patients…”
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Changes in expression of steroid receptors, their downstream target genes and their associated co-regulators during the sequential acquisition of tamoxifen resistance in vitro by SCOTT, D. J, PARKES, A. T, PONCHEL, F, CUMMINGS, M, POOLA, I, SPEIRS, V

“…Tamoxifen resistance (TAMr) in breast cancer is a serious clinical dilemma, with no satisfactory explanation. We hypothesised that changes in the expression of…”
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Potential role of arthroscopy in the management of inflammatory arthritis by GOËB, V, WALSH, C. A. E, REECE, R. J, EMERY, P, PONCHEL, F

“…Despite its advantages in diagnosis, treatment and research, the role of arthroscopy in the management of rheumatic diseases has diminished due to the…”
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Outcome of intensive immunosuppression and autologous stem cell transplantation in patients with severe rheumatoid arthritis is associated with the composition of synovial T cell infiltration by Verburg, R J, Flierman, R, Sont, J K, Ponchel, F, van Dreunen, L, Levarht, E W, Welling, M M, Toes, R E M, Isaacs, J D, van Laar, J M

“…Objective: To determine clinical and immunological correlates of high dose chemotherapy (HDC) + autologous stem cell transplantation (ASCT) in patients with…”
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A 3.8 GHz tunable filter based on ferroelectric interdigitated capacitors by Ghalem, A., Ponchel, F., Remiens, D., Lasri, T.

“…In this paper, a tunable filter using ferroelectric capacitor is described. The interdigitated capacitor (IDC) is based on Barium Strontium Titanate (BST)…”
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LEAD-FREE BNT PIEZOELECTRIC THIN FILMS BY SOL-GEL METHOD by Dargham, S. Abou, Ponchel, F., Soueidan, M., Khoury, A., Assaad, J., Remiens, D., Zaouk, D.

“…The objective of this work is to synthesize lead-free piezoelectric thin films by the Sol-Gel method:bismuth sodium titanate (Bi0.5Na0.5TiO3 or BNT).BNT films…”
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FcγRIIIA‐158V and rheumatoid arthritis: a confirmation study by Morgan, A. W., Keyte, V. H., Babbage, S. J., Robinson, J. I., Ponchel, F., Barrett, J. H., Bhakta, B. B., Bingham, S. J., Buch, M. H., Conaghan, P. G., Gough, A., Green, M., Lawson, C. A., Pease, C. T., Markham, A. F., Ollier, W. E. R., Emery, P., Worthington, J., Isaacs, J. D.

“…Objectives. To develop a robust assay for genotyping the FcγRIIIA‐158V/F polymorphism and to confirm the putative association between the FcγRIIIA‐158V allele…”
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061 Differential leukocyte migration towards chemotactic stimuli in psoriasis by Georgiev, G.P., Ponchel, F., McKimmie, C., Shams, K.

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