Search Results - "POLYAKOV, Nikolay E"

Redox Interactions of Vitamin C and Iron: Inhibition of the Pro-Oxidant Activity by Deferiprone by Timoshnikov, Viktor A, Kobzeva, Tatyana V, Polyakov, Nikolay E, Kontoghiorghes, George J

“…Ascorbic acid (AscH ) is one of the most important vitamins found in the human diet, with many biological functions including antioxidant, chelating, and…”
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Water soluble biocompatible vesicles based on polysaccharides and oligosaccharides inclusion complexes for carotenoid delivery by Polyakov, Nikolay E., Kispert, Lowell D.

“…•Inclusion complexes of carotenoids were characterized by NMR, EPR and optical techniques.•Noncovalent binding with arabinogalactan and glycyrrhizin enhances…”
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Supramolecular Carotenoid Complexes of Enhanced Solubility and Stability-The Way of Bioavailability Improvement by Focsan, A Ligia, Polyakov, Nikolay E, Kispert, Lowell D

“…Carotenoids are natural dyes and antioxidants widely used in food processing and in therapeutic formulations. However, their practical application is…”
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Improving the Treatment Effect of Carotenoids on Alzheimer's Disease through Various Nano-Delivery Systems by Su, Wenjing, Xu, Wenhao, Liu, Enshuo, Su, Weike, Polyakov, Nikolay E

“…Natural bioactive compounds have recently emerged as a current strategy for Alzheimer's disease treatment. Carotenoids, including astaxanthin, lycopene,…”
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Mechanistic Insights of Chelator Complexes with Essential Transition Metals: Antioxidant/Pro-Oxidant Activity and Applications in Medicine by Timoshnikov, Viktor A, Selyutina, Olga Yu, Polyakov, Nikolay E, Didichenko, Victoria, Kontoghiorghes, George J

“…The antioxidant/pro-oxidant activity of drugs and dietary molecules and their role in the maintenance of redox homeostasis, as well as the implications in…”
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Preparation of curcumin self-micelle solid dispersion with enhanced bioavailability and cytotoxic activity by mechanochemistry by Zhang, Qihong, Polyakov, Nikolay E., Chistyachenko, Yulia S., Khvostov, Mikhail V., Frolova, Tatjana S., Tolstikova, Tatjana G., Dushkin, Alexandr V., Su, Weike

“…An amorphous solid dispersion (SD) of curcumin (Cur) with disodium glycyrrhizin (Na 2 GA) was prepared by mechanical ball milling. Curcumin loaded micelles…”
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The Endless World of Carotenoids-Structural, Chemical and Biological Aspects of Some Rare Carotenoids by Polyakov, Nikolay E, Focsan, A Ligia, Gao, Yunlong, Kispert, Lowell D

“…Carotenoids are a large and diverse group of compounds that have been shown to have a wide range of potential health benefits. While some carotenoids have been…”
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Photochemical and Optical Properties of Water-Soluble Xanthophyll Antioxidants: Aggregation vs Complexation by Polyakov, Nikolay E, Magyar, Adam, Kispert, Lowell D

“…Xanthophyll carotenoids can self-assemble in aqueous solution to form J- and H-type aggregates. This feature significantly changes the photophysical and…”
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Metal Complexes of Omadine ( N -Hydroxypyridine-2-thione): Differences of Antioxidant and Pro-Oxidant Behavior in Light and Dark Conditions with Possible Toxicity Implications by Selyutina, Olga Yu, Timoshnikov, Viktor A, Polyakov, Nikolay E, Kontoghiorghes, George J

“…Omadine or -hydroxypyridine-2-thione and its metal complexes are widely used in medicine and show bactericidal, fungicidal, anticancer, and photochemical…”
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pH-Sensitive Glycyrrhizin Based Vesicles for Nifedipine Delivery by Selyutina, Olga Yu, Mastova, Anna V, Shelepova, Ekaterina A, Polyakov, Nikolay E

“…Glycyrrhizic acid, or glycyrrhizin (GA), a major active component of licorice root, has been widely used in traditional Chinese and Japanese medicine since…”
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Chiral Linked Systems as a Model for Understanding D-Amino Acids Influence on the Structure and Properties of Amyloid Peptides by Ageeva, Aleksandra A, Doktorov, Alexander B, Polyakov, Nikolay E, Leshina, Tatyana V

“…In this review, we provide an illustration of the idea discussed in the literature of using model compounds to study the effect of substitution of L- for…”
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Solubilization and stabilization of macular carotenoids by water soluble oligosaccharides and polysaccharides by Apanasenko, Irina E, Selyutina, Olga Yu, Polyakov, Nikolay E, Suntsova, Lyubov P, Meteleva, Elizaveta S, Dushkin, Alexander V, Vachali, Preejith, Bernstein, Paul S

“…Xanthophyll carotenoids zeaxanthin and lutein play a special role in the prevention and treatment of visual diseases. These carotenoids are not produced by the…”
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Impact of Non-Covalent Interactions of Chiral Linked Systems in Solution on Photoinduced Electron Transfer Efficiency by Magin, Ilya M, Pushkin, Ivan A, Ageeva, Aleksandra A, Martianova, Sofia O, Polyakov, Nikolay E, Doktorov, Alexander B, Leshina, Tatyana V

“…It is well-known that non-covalent interactions play an essential role in the functioning of biomolecules in living organisms. The significant attention of…”
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Antioxidant Activity of Deferasirox and Its Metal Complexes in Model Systems of Oxidative Damage: Comparison with Deferiprone by Timoshnikov, Viktor A., Kichigina, Lilia A., Selyutina, Olga Yu, Polyakov, Nikolay E., Kontoghiorghes, George J.

“…Deferasirox is an orally active, lipophilic iron chelating drug used on thousands of patients worldwide for the treatment of transfusional iron overload. The…”
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Solubility, Permeability, Anti-Inflammatory Action and In Vivo Pharmacokinetic Properties of Several Mechanochemically Obtained Pharmaceutical Solid Dispersions of Nimesulide by Wei, Wei, Evseenko, Veronica I, Khvostov, Mikhail V, Borisov, Sergey A, Tolstikova, Tatyana G, Polyakov, Nikolay E, Dushkin, Aleksandr V, Xu, Wenhao, Min, Lu, Su, Weike

“…Nimesulide (NIM, -(4-nitro-2-phenoxyphenyl)methanesulfonamide) is a relatively new nonsteroidal anti-inflammatory analgesic drug. It is practically insoluble…”
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The Interaction of the Transmembrane Domain of SARS-CoV-2 E-Protein with Glycyrrhizic Acid in Lipid Bilayer by Kononova, Polina A, Selyutina, Olga Yu, Polyakov, Nikolay E

“…The interaction of the transmembrane domain of SARS-CoV-2 E-protein with glycyrrhizic acid in a model lipid bilayer (small isotropic bicelles) is demonstrated…”
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NMR Study of Water-Soluble Carotenoid Crocin: Formation of Mixed Micelles, Interaction with Lipid Membrane and Antioxidant Activity by Su, Wenjing, Mastova, Anna V, Ul'yanova, Maya A, Kononova, Polina A, Selyutina, Olga Yu, Evseenko, Veronika I, Meteleva, Elizaveta S, Dushkin, Alexander V, Su, Weike, Polyakov, Nikolay E

“…Crocin is a unique water-soluble carotenoid found in crocus and gardenia flowers. Crocin has been shown to have a variety of pharmacological activities, such…”
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The Interaction of Anthracycline Based Quinone-Chelators with Model Lipid Membranes: 1H NMR and MD Study by Selyutina, Olga Yu, Mastova, Anna V., Polyakov, Nikolay E.

“…Anthracycline antibiotics, e.g., doxorubicin, daunomycin, and other anthraquinones, are an important family of antitumor agents widely used in chemotherapy,…”
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Photoinduced Processes in Lysine-Tryptophan-Lysine Tripeptide with L and D Tryptophan by Ageeva, Aleksandra A, Lukyanov, Roman S, Martyanova, Sofia O, Magin, Ilya M, Kruppa, Alexander I, Polyakov, Nikolay E, Plyusnin, Victor F, Doktorov, Alexander B, Leshina, Tatyana V

“…Optical isomers of short peptide Lysine-Tryptophan-Lysine (Lys-{L/D-Trp}-Lys) and Lys-Trp-Lys with an acetate counter-ion were used to study photoinduced…”
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Preparation of DNC Solid Dispersion by a Mechanochemical Method with Glycyrrhizic Acid and Polyvinylpyrrolidone to Enhance Bioavailability and Activity by Lu, Min, Wei, Wei, Xu, Wenhao, Polyakov, Nikolay E, Dushkin, Alexandr V, Su, Weike

“…To exploit aqueous-soluble formulation and improve the anticoccidial activity of 4,4'-dinitrocarbanilide (DNC, active component of nicarbazin), this paper…”
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