Search Results - "POLMAN, C. H"

Differential diagnosis of suspected multiple sclerosis: a consensus approach by Miller, DH, Weinshenker, BG, Filippi, M, Banwell, BL, Cohen, JA, Freedman, MS, Galetta, SL, Hutchinson, M, Johnson, RT, Kappos, L, Kira, J, Lublin, FD, McFarland, HF, Montalban, X, Panitch, H, Richert, JR, Reingold, SC, Polman, CH

“…Background and objectives Diagnosis of multiple sclerosis (MS) requires exclusion of diseases that could better explain the clinical and paraclinical findings…”
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Treatment with interferon beta-1b delays conversion to clinically definite and McDonald MS in patients with clinically isolated syndromes by KAPPOS, L, POLMAN, C. H, POHL, C, SANDBRINK, R, FREEDMAN, M. S, EDAN, G, HARTUNG, H. P, MILLER, D. H, MONTALBAN, X, BARKHOF, F, BAUER, L, JAKOBS, P

“…To assess efficacy, safety, and tolerability of every-other-day interferon beta-1b treatment in patients with a first clinical event suggestive of multiple…”
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Postmortem verification of MS cortical lesion detection with 3D DIR by SEEWANN, A, KOOI, E.-J, ROOSENDAAL, S. D, POUWELS, P. J. W, WATTJES, M. P, VAN DER VALK, P, BARKHOF, F, POLMAN, C. H, GEURTS, J. J. G

“…To assess the sensitivity and specificity of 3D double inversion recovery (DIR) MRI for detecting multiple sclerosis (MS) cortical lesions (CLs) using a direct…”
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EFNS guidelines on diagnosis and management of neuromyelitis optica by Sellner, J., Boggild, M., Clanet, M., Hintzen, R. Q., Illes, Z., Montalban, X., Du Pasquier, R. A., Polman, C. H., Sorensen, P. S., Hemmer, B.

“…Background and purpose:  Neuromyelitis optica (NMO) or Devic′s disease is a rare inflammatory and demyelinating autoimmune disorder of the central nervous…”
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Structural degree predicts functional network connectivity: A multimodal resting-state fMRI and MEG study by Tewarie, P., Hillebrand, A., van Dellen, E., Schoonheim, M.M., Barkhof, F., Polman, C.H., Beaulieu, C., Gong, G., van Dijk, B.W., Stam, C.J.

“…Communication between neuronal populations in the human brain is characterized by complex functional interactions across time and space. Recent studies have…”
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Functional brain network analysis using minimum spanning trees in Multiple Sclerosis: An MEG source-space study by Tewarie, P., Hillebrand, A., Schoonheim, M.M., van Dijk, B.W., Geurts, J.J.G., Barkhof, F., Polman, C.H., Stam, C.J.

“…Cognitive dysfunction in Multiple Sclerosis (MS) is closely related to altered functional brain network topology. Conventional network analyses to compare…”
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Bidirectional trans-synaptic axonal degeneration in the visual pathway in multiple sclerosis by Balk, L J, Steenwijk, M D, Tewarie, P, Daams, M, Killestein, J, Wattjes, M P, Vrenken, H, Barkhof, F, Polman, C H, Uitdehaag, B M J, Petzold, A

“…Objective To investigate the coexistence of anterograde and retrograde trans-synaptic axonal degeneration, and to explore the relationship between selective…”
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Magnetic resonance imaging correlates of physical disability in relapse onset multiple sclerosis of long disease duration by Kearney, H, Rocca, MA, Valsasina, P, Balk, L, Sastre-Garriga, J, Reinhardt, J, Ruggieri, S, Rovira, A, Stippich, C, Kappos, L, Sprenger, T, Tortorella, P, Rovaris, M, Gasperini, C, Montalban, X, Geurts, JJG, Polman, CH, Barkhof, F, Filippi, M, Altmann, DR, Ciccarelli, O, Miller, DH, Chard, DT

“…Background: Understanding long-term disability in multiple sclerosis (MS) is a key goal of research; it is relevant to how we monitor and treat the disease…”
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MRI outcomes in a placebo-controlled trial of natalizumab in relapsing MS by MILLER, D. H, SOON, D, KAPPOS, L, HUTCHINSON, M, HAVRDOVA, E, LUBLIN, F. D, GIOVANNONI, G, WAJGT, A, RUDICK, R, LYNN, F, PANZARA, M. A, SANDROCK, A. W, FERNANDO, K. T, MACMANUS, D. G, BARKER, G. J, YOUSRY, T. A, FISHER, E, O'CONNOR, P. W, PHILLIPS, J. T, POLMAN, C. H

“…In a 2-year, placebo-controlled trial (the Natalizumab Safety and Efficacy in Relapsing Remitting Multiple Sclerosis [AFFIRM] study), involving 942 patients…”
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Oxysterols and cholesterol precursors correlate to magnetic resonance imaging measures of neurodegeneration in multiple sclerosis by van de Kraats, C, Killestein, J, Popescu, V, Rijkers, E, Vrenken, H, Lütjohann, D, Barkhof, F, Polman, CH, Teunissen, CE

“…Background: Cholesterol homeostasis is important for formation and maintenance of myelin and axonal membranes in the central nervous system (CNS). The…”
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Greater loss of axons in primary progressive multiple sclerosis plaques compared to secondary progressive disease by Tallantyre, E. C., Bø, L., Al-Rawashdeh, O., Owens, T., Polman, C. H., Lowe, J., Evangelou, N.

“…The pathological substrate of progressive disability in multiple sclerosis is hypothesized to be axonal loss. Differences in the demographic, pathological and…”
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Disease course heterogeneity and OCT in multiple sclerosis by Balk, LJ, Tewarie, P, Killestein, J, Polman, CH, Uitdehaag, BMJ, Petzold, A

“…Background: The heterogeneity of the disease course in multiple sclerosis (MS) remains a challenge for patient management and clinical trials. Objective: The…”
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Differences in cognitive impairment of relapsing remitting, secondary, and primary progressive MS by HUIJBREGTS, S. C. J, KALKERS, N. F, DE SONNEVILLE, L. M. J, DE GROOT, V, REULING, I. E. W, POLMAN, C. H

“…To investigate the cognitive skills of patients with relapsing remitting multiple sclerosis (RRMS), secondary progressive MS (SPMS), and primary progressive MS…”
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Sample sizes for brain atrophy outcomes in trials for secondary progressive multiple sclerosis by ALTMANN, D. R, JASPERSE, B, WAGNER, K, YOUSRY, T. A, MILLER, D. H, BARKHOF, F, BECKMANN, K, FILIPPI, M, KAPPOS, L. D, MOLYNEUX, P, POLMAN, C. H, POZZILLI, C, THOMPSON, A. J

“…Progressive brain atrophy in multiple sclerosis (MS) may reflect neuroaxonal and myelin loss and MRI measures of brain tissue loss are used as outcome measures…”
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Changes in functional network centrality underlie cognitive dysfunction and physical disability in multiple sclerosis by Schoonheim, M M, Geurts, J J G, Wiebenga, O T, De Munck, J C, Polman, C H, Stam, C J, Barkhof, F, Wink, A M

“…Background: Cognitive dysfunction in multiple sclerosis (MS) has a large impact on the quality of life and is poorly understood. Objective: The aim of this…”
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POSTWITHDRAWAL REBOUND INCREASE IN T2 LESIONAL ACTIVITY IN NATALIZUMAB-TREATED MS PATIENTS by VELLINGA, M. M, CASTELIJNS, J. A, BARKHOF, F, UITDEHAAG, B. M. J, POLMAN, C. H

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Evaluation of the symbol digit modalities test (SDMT) and MS neuropsychological screening questionnaire (MSNQ) in natalizumab-treated MS patients over 48 weeks by Morrow, SA, O'Connor, PW, Polman, CH, Goodman, AD, Kappos, L, Lublin, FD, Rudick, RA, Jurgensen, S, Paes, D, Forrestal, F, Benedict, RHB

“…Background and Objectives: Brief cognitive tests to monitor cognitive impairment in patients with multiple sclerosis (MS) are needed. Methods: Performance on…”
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Early detection of neutralizing antibodies to interferon-beta in multiple sclerosis patients: binding antibodies predict neutralizing antibody development by Hegen, H, Millonig, A, Bertolotto, A, Comabella, M, Giovanonni, G, Guger, M, Hoelzl, M, Khalil, M, Killestein, J, Lindberg, R, Malucchi, S, Mehling, M, Montalban, X, Polman, CH, Rudzki, D, Schautzer, F, Sellebjerg, F, Sørensen, PS, Deisenhammer, F

“…Background: Neutralizing antibodies (NAb) affect efficacy of interferon-beta (IFN-b) treatment in multiple sclerosis (MS) patients. NAbs evolve in up to 44% of…”
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Normal CSF ferritin levels in MS suggest against etiologic role of chronic venous insufficiency by WORTHINGTON, V, KILLESTEIN, J, EIKELENBOOM, M. J, TEUNISSEN, C. E, BARKHOF, F, POLMAN, C. H, UITDEHAAG, B. M. J, PETZOLD, A

“…Chronic cerebrospinal venous insufficiency (CCSVI) has been suggested to be a possible cause of multiple sclerosis (MS). If the presumed mechanism of venous…”
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Spinal cord abnormalities in recently diagnosed MS patients: Added value of spinal MRI examination by BOT, J. C. J, BARKHOF, F, POLMAN, C. H, LYCKLAMA A NIJEHOLT, G. J, DE GROOT, V, BERGERS, E, ADER, H. J, CASTELIJNS, J. A

“…The most recent diagnostic criteria for multiple sclerosis (MS) ascertain that findings from spinal cord MRI can be used to demonstrate dissemination in space…”
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