Search Results - "POLLIN, Toni I"

Omentin Plasma Levels and Gene Expression Are Decreased in Obesity by DE SOUZA BATISTA, Celia M, YANG, Rong-Ze, FRIED, Susan K, GONG, Da-Wei, SHULDINER, Alan R, POLLIN, Toni I, MCLENITHAN, John C, LEE, Mi-Jeong, GLYNRI, Nicole M, YU, Dao-Zhan, PRAY, Jessica, NDUBUIZU, Kelechi, PATIL, Susheel, SCHWARTZ, Alan, KLIGMAN, Mark

“…Omentin Plasma Levels and Gene Expression Are Decreased in Obesity Celia M. de Souza Batista 1 2 , Rong-Ze Yang 1 , Mi-Jeong Lee 1 , Nicole M. Glynn 1 ,…”
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Common Variants in 40 Genes Assessed for Diabetes Incidence and Response to Metformin and Lifestyle Intervention in the Diabetes Prevention Program by JABLONSKI, Kathleen A, MCATEER, Jarred B, ALTSHULER, David, FLOREZ, Jose C, DE BAKKER, Paul I. W, FRANKS, Paul W, POLLIN, Toni I, HANSON, Robert L, SAXENA, Richa, FOWLER, Sarah, SHULDINER, Alan R, KNOWLER, William C

“…Genome-wide association studies have begun to elucidate the genetic architecture of type 2 diabetes. We examined whether single nucleotide polymorphisms (SNPs)…”
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Challenges and strategies for implementing genomic services in diverse settings: experiences from the Implementing GeNomics In pracTicE (IGNITE) network by Sperber, Nina R, Carpenter, Janet S, Cavallari, Larisa H, J Damschroder, Laura, Cooper-DeHoff, Rhonda M, Denny, Joshua C, Ginsburg, Geoffrey S, Guan, Yue, Horowitz, Carol R, Levy, Kenneth D, Levy, Mia A, Madden, Ebony B, Matheny, Michael E, Pollin, Toni I, Pratt, Victoria M, Rosenman, Marc, Voils, Corrine I, W Weitzel, Kristen, Wilke, Russell A, Ryanne Wu, R, Orlando, Lori A

“…To realize potential public health benefits from genetic and genomic innovations, understanding how best to implement the innovations into clinical care is…”
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A stepwise approach to implementing pharmacogenetic testing in the primary care setting by Weitzel, Kristin Wiisanen, Duong, Benjamin Q, Arwood, Meghan J, Owusu-Obeng, Aniwaa, Abul-Husn, Noura S, Bernhardt, Barbara A, Decker, Brian, Denny, Joshua C, Dietrich, Eric, Gums, John, Madden, Ebony B, Pollin, Toni I, Wu, Rebekah Ryanne, Haga, Susanne B, Horowitz, Carol R

“…Pharmacogenetic testing can help identify primary care patients at increased risk for medication toxicity, poor response or treatment failure and inform drug…”
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A rare functional cardioprotective APOC3 variant has risen in frequency in distinct population isolates by Tachmazidou, Ioanna, Dedoussis, George, Southam, Lorraine, Farmaki, Aliki-Eleni, Ritchie, Graham R. S., Xifara, Dionysia K., Matchan, Angela, Hatzikotoulas, Konstantinos, Rayner, Nigel W., Chen, Yuan, Pollin, Toni I., O’Connell, Jeffrey R., Yerges-Armstrong, Laura M., Kiagiadaki, Chrysoula, Panoutsopoulou, Kalliope, Schwartzentruber, Jeremy, Moutsianas, Loukas, Tsafantakis, Emmanouil, Tyler-Smith, Chris, McVean, Gil, Xue, Yali, Zeggini, Eleftheria

“…Isolated populations can empower the identification of rare variation associated with complex traits through next generation association studies, but the…”
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Acute-phase serum amyloid A: an inflammatory adipokine and potential link between obesity and its metabolic complications by Yang, Rong-Ze, Lee, Mi-Jeong, Hu, Hong, Pollin, Toni I, Ryan, Alice S, Nicklas, Barbara J, Snitker, Soren, Horenstein, Richard B, Hull, Kristen, Goldberg, Nelson H, Goldberg, Andrew P, Shuldiner, Alan R, Fried, Susan K, Gong, Da-Wei

“…Obesity is associated with low-grade chronic inflammation, and serum markers of inflammation are independent risk factors for cardiovascular disease (CVD)…”
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Implementation of pharmacogenetics: The University of Maryland personalized anti-platelet pharmacogenetics program by Shuldiner, Alan R., Palmer, Kathleen, Pakyz, Ruth E., Alestock, Tameka D., Maloney, Kristin A., O'Neill, Courtney, Bhatty, Shaun, Schub, Jamie, Overby, Casey Lynnette, Horenstein, Richard B., Pollin, Toni I., Kelemen, Mark D., Beitelshees, Amber L., Robinson, Shawn W., Blitzer, Miriam G., McArdle, Patrick F., Brown, Lawrence, Jeng, Linda Jo Bone, Zhao, Richard Y., Ambulos, Nicholas, Vesely, Mark R.

“…Despite a substantial evidence base, implementation of pharmacogenetics into routine patient care has been slow due to a number of non‐trivial practical…”
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Gender differences in first and secondhand smoke exposure, spirometric lung function and cardiometabolic health in the old order Amish: A novel population without female smoking by Reed, Robert M, Dransfield, Mark T, Eberlein, Michael, Miller, Michael, Netzer, Giora, Pavlovich, Mary, Pollin, Toni I, Scharf, Steven M, Shuldiner, Alan R, Sin, Don, Mitchell, Braxton D

“…Due to their relatively homogeneous lifestyle and living environment, the Amish offer a novel opportunity to study the health associations of tobacco smoke…”
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Monogenic diabetes: a gateway to precision medicine in diabetes by Zhang, Haichen, Colclough, Kevin, Gloyn, Anna L, Pollin, Toni I

“…Monogenic diabetes refers to diabetes mellitus (DM) caused by a mutation in a single gene and accounts for approximately 1%-5% of diabetes. Correct diagnosis…”
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Statistical evidence for high‐penetrance MODY‐causing genes in a large population‐based cohort by Billings, Liana K., Shi, Zhuqing, Resurreccion, W. Kyle, Wang, Chi‐Hsiung, Wei, Jun, Pollin, Toni I., Udler, Miriam S., Xu, Jianfeng

“…Aims Numerous genes have been proposed as causal for maturity‐onset diabetes of the young (MODY). Scoring systems to annotate mutation pathogenicity have been…”
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Polyherbal dietary supplementation for prediabetic adults: study protocol for a randomized controlled trial by Feinberg, Termeh, Wieland, L Susan, Miller, Larry E, Munir, Kashif, Pollin, Toni I, Shuldiner, Alan R, Amoils, Steve, Gallagher, Lisa, Bahr-Robertson, Mary, D'Adamo, Christopher R

“…Prediabetes describes a state of hyperglycemia outside of normal limits that does not meet the criteria for diabetes diagnosis, is generally symptomless, and…”
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Enrollment of underrepresented racial and ethnic groups in the Rare and Atypical Diabetes Network (RADIANT) by Tosur, Mustafa, Gandolfo, Laura, Balasubramanyam, Ashok, Naylor, Rochelle N, Pollin, Toni I, Rasouli, Neda, Cromer, Sara J, Buse, John B, Redondo, Maria J

“…Diabetes mellitus in underrepresented racial and ethnic groups (URG) is rapidly increasing in incidence and has worse outcomes than diabetes in non-Hispanic…”
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Extension of Type 2 Diabetes Genome-Wide Association Scan Results in the Diabetes Prevention Program by MOORE, Allan F, JABLONSKI, Kathleen A, FLOREZ, Jose C, MCATEER, Jarred B, SAXENA, Richa, POLLIN, Toni I, FRANKS, Paul W, HANSON, Robert L, SHULDINER, Alan R, KNOWLER, William C, ALTSHULER, David

“…Extension of Type 2 Diabetes Genome-Wide Association Scan Results in the Diabetes Prevention Program Allan F. Moore 1 2 3 4 † , Kathleen A. Jablonski 5 ,…”
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Prevalence, control, and treatment of diabetes, hypertension, and high cholesterol in the Amish by He, Shisi, Ryan, Kathleen A, Streeten, Elizabeth A, McArdle, Patrick F, Daue, Melanie, Trubiano, Donna, Rohrer, Yvonne, Donnelly, Patrick, Drolet, Maryann, Newcomer, Sylvia, Shaub, Susan, Weitzel, Nancy, Shuldiner, Alan R, Pollin, Toni I, Mitchell, Braxton D

“…BackgroundThe burden of diabetes and cardiovascular risk is not uniform across the USA, with much of this disparity tracking differences in socioeconomic…”
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Predicting diabetic nephropathy using a multifactorial genetic model by Blech, Ilana, Katzenellenbogen, Mark, Katzenellenbogen, Alexandra, Wainstein, Julio, Rubinstein, Ardon, Harman-Boehm, Ilana, Cohen, Joseph, Pollin, Toni I, Glaser, Benjamin

“…The tendency to develop diabetic nephropathy is, in part, genetically determined, however this genetic risk is largely undefined. In this proof-of-concept…”
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Vitamin and Supplement Use among Old Order Amish: Sex-Specific Prevalence and Associations with Use by Reed, Robert M., MD, Reed, Anna W., MD, McArdle, Patrick F., PhD, Miller, Michael, MD, Pollin, Toni I., PhD, Shuldiner, Alan R., MD, Steinle, Nanette I., MD, Mitchell, Braxton D., PhD

“…Abstract Background Complementary and alternative medicine (CAM) in the form of vitamin and supplement use is increasingly prevalent in the United States. The…”
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Personalized medicine in diabetes mellitus: current opportunities and future prospects by Kleinberger, Jeffrey W., Pollin, Toni I.

“…Diabetes mellitus affects approximately 382 million individuals worldwide and is a leading cause of morbidity and mortality. Over 40 and nearly 80 genetic loci…”
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Living the good life? Mortality and hospital utilization patterns in the Old Order Amish by Mitchell, Braxton D, Lee, Woei-Jyh, Tolea, Magdalena I, Shields, Kelsey, Ashktorab, Zahra, Magder, Laurence S, Ryan, Kathleen A, Pollin, Toni I, McArdle, Patrick F, Shuldiner, Alan R, Schäffer, Alejandro A

“…Lifespan increases observed in the United States and elsewhere throughout the developed world, have been attributed in part to improvements in medical care…”
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An openly available online tool for implementing the ACMG/AMP standards and guidelines for the interpretation of sequence variants by Kleinberger, Jeffrey, Maloney, Kristin A., Pollin, Toni I., Jeng, Linda Jo Bone

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Undiagnosed MODY: Time for Action by Kleinberger, Jeffrey W., Pollin, Toni I.

“…Maturity-onset diabetes of the young (MODY) is a monogenic form of diabetes that accounts for at least 1 % of all cases of diabetes mellitus. MODY classically…”
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