Search Results - "POLLAKIS, G"

Improved metastasis‐free survival in nonadjuvantly treated postmenopausal breast cancer patients with chemokine receptor 5 del32 frameshift mutations by Span, P.N., Pollakis, G., Paxton, W.A., Sweep, F.C.G.J., Foekens, J.A., Martens, J.W.M., Sieuwerts, A.M., van Laarhoven, H.W.M.

“…The CC‐chemokine receptor CCR5 has been associated with cancer progression and metastasis. CCR5 blockers such as Maraviroc are tested in metastatic cancer…”
Get full text

Apelin, the Natural Ligand of the Orphan Seven-Transmembrane Receptor APJ, Inhibits Human Immunodeficiency Virus Type 1 Entry by Cayabyab, M, Hinuma, S, Farzan, M, Choe, H, Fukusumi, S, Kitada, C, Nishizawa, N, Hosoya, M, Nishimura, O, Messele, T, Pollakis, G, Goudsmit, J, Fujino, M, Sodroski, J

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Human Immunodeficiency Virus Type 1 Subtypes Have a Distinct Long Terminal Repeat That Determines the Replication Rate in a Host-Cell-Specific Manner by VAN OPIJNEN, Tim, JEENINGA, Rienk E, BOERLIJST, Maarten C, POLLAKIS, Georgios P, ZETTERBERG, Veera, SALMINEN, Mika, BERKHOUT, Ben

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

P07-10. Natural compounds in bodily fluids which bind DC-SIGN and prevent HIV-1 capture and transfer to CD4 cells by Stax, MJ, Pollakis, G, Sprenger, RR, Melchers, M, van Montfort, T, Sanders, RW, Speijer, D, Paxton, WA

Get full text

Respiration of Bloodstream Forms of the Parasite Trypanosoma brucei brucei Is Dependent on a Plant-like Alternative Oxidase by Clarkson, A B C, Bienen, E J, Pollakis, G, Grady, R W

“…CoQ links the sn-glycerol-3-phosphate dehydrogenase and oxidase components of the cyanide-insensitive, non-cytochrome-mediated respiratory system of…”
Get full text

Identification of a genetic subcluster of HIV type 1 subtype C (C') widespread in Ethiopia by Abebe, A, Pollakis, G, Fontanet, A L, Fisseha, B, Tegbaru, B, Kliphuis, A, Tesfaye, G, Negassa, H, Cornelissen, M, Goudsmit, J, Rinke de Wit, T F

“…Others and we have previously shown that subtype C is the predominant HIV-1 subtype and the major cause of AIDS in Ethiopia. The present study shows that…”
Get more information

Nucleocapsid-specific T cell responses associate with control of SARS-CoV-2 in the upper airways before seroconversion by Eser, Tabea M., Baranov, Olga, Huth, Manuel, Ahmed, Mohammed I. M., Deák, Flora, Held, Kathrin, Lin, Luming, Pekayvaz, Kami, Leunig, Alexander, Nicolai, Leo, Pollakis, Georgios, Buggert, Marcus, Price, David A., Rubio-Acero, Raquel, Reich, Jakob, Falk, Philine, Markgraf, Alissa, Puchinger, Kerstin, Castelletti, Noemi, Olbrich, Laura, Vanshylla, Kanika, Klein, Florian, Wieser, Andreas, Hasenauer, Jan, Kroidl, Inge, Hoelscher, Michael, Geldmacher, Christof

“…Despite intensive research since the emergence of SARS-CoV-2, it has remained unclear precisely which components of the early immune response protect against…”
Get full text

Lewis X component in human milk binds DC-SIGN and inhibits HIV-1 transfer to CD4+ T lymphocytes by Naarding, Marloes A, Ludwig, Irene S, Groot, Fedde, Berkhout, Ben, Geijtenbeek, Teunis B H, Pollakis, Georgios, Paxton, William A

“…DC-specific ICAM3-grabbing non-integrin (DC-SIGN), which is expressed on DCs, can interact with a variety of pathogens such as HIV-1, hepatitis C, Ebola,…”
Get full text

Systematic comparison of HIV-1 Envelope-specific IgG responses induced by different vaccination regimens: Can we steer IgG recognition towards regions of viral vulnerability? by Horvath, Augusta, Rogers, Lisa, Pollakis, Georgios, Baranov, Olga, Pieroth, Nora, Joseph, Sarah, Chachage, Mkunde, Heitzer, Asli, Maganga, Lucas, Msafiri, Frank, Joachim, Agricola, Viegas, Edna, Eller, Leigh-Anne, Kibuuka, Hannah, Rerks-Ngarm, Supachai, Pitisuttithum, Punnee, Nitayapan, Sorachai, Dhitavat, Jittima, Premsri, Nakorn, Fidler, Sarah, Shattock, Robin J, Robb, Merlin Lee, Weber, Jonathan, McCormack, Sheena, Munseri, Patricia Jane, Lyamuya, Eligius, Nilsson, Charlotta, Kroidl, Arne, Hoelscher, Michael, Wagner, Ralf, Geldmacher, Christof, Held, Kathrin

“…Immunogens and vaccination regimens can influence patterns of immune-epitope recognition, steering them towards or away from epitopes of potential viral…”
Get full text

Improved metastasis-free survival in nonadjuvantly treated postmenopausal breast cancer patients with chemokine receptor 5 del32 frameshift mutations: CCR5 genotype and breast cancer prognosis by Span, P.N., Pollakis, G., Paxton, W.A., Sweep, F.C.G.J., Foekens, J.A., Martens, J.W.M., Sieuwerts, A.M., van Laarhoven, H.W.M.

Get full text

Induction of Identical IgG HIV-1 Envelope Epitope Recognition Patterns After Initial HIVIS-DNA/MVA-CMDR Immunization and a Late MVA-CMDR Boost by Joachim, Agricola, Ahmed, Mohamed I M, Pollakis, Georgios, Rogers, Lisa, Hoffmann, Verena S, Munseri, Patricia, Aboud, Said, Lyamuya, Eligius F, Bakari, Muhammad, Robb, Merlin L, Wahren, Britta, Sandstrom, Eric, Nilsson, Charlotta, Biberfeld, Gunnel, Geldmacher, Christof, Held, Kathrin

“…In the RV144 trial, to date the only HIV-1 vaccine efficacy trial demonstrating a modestly reduced risk of HIV-1 acquisition, antibody responses toward the HIV…”
Get full text

Dendritic cells potently purge latent HIV-1 beyond TCR-stimulation, activating the PI3K-Akt-mTOR pathway by van Montfort, Thijs, van der Sluis, Renée, Darcis, Gilles, Beaty, Doyle, Groen, Kevin, Pasternak, Alexander O., Pollakis, Georgios, Vink, Monique, Westerhout, Ellen M., Hamdi, Mohamed, Bakker, Margreet, van der Putten, Boas, Jurriaans, Suzanne, Prins, Jan H., Jeeninga, Rienk, Thomas, Adri A.M., Speijer, Dave, Berkhout, Ben

“…The latent HIV-1 reservoir in treated patients primarily consists of resting memory CD4+ T cells. Stimulating the T-cell receptor (TCR), which facilitates…”
Get full text

Envelope-Specific Recognition Patterns of HIV Vaccine-Induced IgG Antibodies Are Linked to Immunogen Structure and Sequence by Nadai, Yuka, Held, Kathrin, Joseph, Sarah, Ahmed, Mohamed I M, Hoffmann, Verena S, Peterhoff, David, Missanga, Marco, Bauer, Asli, Joachim, Agricola, Reimer, Ulf, Zerweck, Johannes, McCormack, Sheena, Cope, Alethea V, Tatoud, Roger, Shattock, Robin J, Robb, Merlin Lee, Sandstroem, Eric G, Hoelscher, Michael, Maboko, Leonard, Bakari, Muhammad, Kroidl, Arne, Wagner, Ralf, Weber, Jonathan, Pollakis, Georgios, Geldmacher, Christof

“…A better understanding of the parameters influencing vaccine-induced IgG recognition of individual antigenic regions and their variants within the HIV Envelope…”
Get full text

Mitochondrial membrane modifications induced by adriamycin-mediated electron transport by Goormaghtigh, E, Pollakis, G, Ruysschaert, J M

“…Adriamycin (ADM) was found to have a two-step mode of action on the cardiac mitochondrial membrane. (1) An interaction with cardiolipin (CL) resulted in the…”
Get more information

A new class of free radical scavengers reducing adriamycin mitochondrial toxicity by Praet, M, Calderon, P B, Pollakis, G, Roberfroid, M, Ruysschaert, J M

“…Beef heart mitochondria were incubated with ADM and NADH. An adriamycin semiquinone radical was detected using ESR spectroscopy. The semiquinone radical…”
Get more information

HIV RNA levels in transmission sources only weakly predict plasma viral load in recipients by VAN DER KUYL, Antoinette C, JURRIAANS, Suzanne, POLLAKIS, Georgios, BAKKER, Margreet, CORNELISSEN, Marion

“…In a typical HIV-1-infected patient, plasma viral load (pVL) increases steeply in the first week after acute infection, then decreases as the immune system…”
Get full text

N-Linked Glycosylation of the HIV Type-1 gp120 Envelope Glycoprotein as a Major Determinant of CCR5 and CXCR4 Coreceptor Utilization by Pollakis, G, Kang, S, Kliphuis, A, Chalaby, M I, Goudsmit, J, Paxton, W A

“…The variable V1V2 and V3 regions of the human immunodeficiency virus type-1 (HIV-1) envelope glycoprotein (gp120) can influence viral coreceptor usage. To…”
Get full text

Increased HIV-1 Activity in Anal High-Grade Squamous Intraepithelial Lesions Compared With Unaffected Anal Mucosa in Men Who Have Sex With Men by Pollakis, Georgios, Richel, Olivier, Vis, Joost D., Prins, Jan M., Paxton, William A., de Vries, Henry J. C.

“…We studied 3 patients with focal intra-anal tissue high-grade squamous intraepithelial lesions (HSILs). All had increased human immunodeficiency virus type 1…”
Get full text

HIV type 1 mother-to-child transmission facilitated by distinctive glycosylation sites in the gp120 envelope glycoprotein by Baan, Elly, de Ronde, Anthony, Luchters, Stanley, Vyankandondera, Joseph, Lange, Joep M, Pollakis, Georgios, Paxton, William A

“…The human immunodeficiency virus type 1 (HIV-1) characteristics associated with mother-to-child transmission (MTCT) are still poorly understood. We studied a…”
Get more information

Intrapatient Alterations in the Human Immunodeficiency Virus Type 1 gp120 V1V2 and V3 Regions Differentially Modulate Coreceptor Usage, Virus Inhibition by CC/CXC Chemokines, Soluble CD4, and the b12 and 2G12 Monoclonal Antibodies by NABATOV, Alexey A, POLLAKIS, Georgios, LINNEMANN, Thomas, KLIPHIUS, Aletta, CHALABY, Moustapha I. M, PAXTON, William A

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text