Search Results - "POLKEY, C"

Reward-related reversal learning after surgical excisions in orbito-frontal or dorsolateral prefrontal cortex in humans by Hornak, J, O'Doherty, J, Bramham, J, Rolls, E T, Morris, R G, Bullock, P R, Polkey, C E

“…Neurophysiological studies in primates and neuroimaging studies in humans suggest that the orbito-frontal cortex is involved in representing the reward value…”
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Changes in emotion after circumscribed surgical lesions of the orbitofrontal and cingulate cortices by Hornak, J., Bramham, J., Rolls, E. T., Morris, R. G., O’Doherty, J., Bullock, P. R., Polkey, C. E.

“…To analyse the functions of different parts of the prefrontal cortex in emotion, patients with different prefrontal surgical excisions were compared on four…”
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The impact of early and late damage to the human amygdala on ‘theory of mind’ reasoning by Shaw, P., Lawrence, E. J., Radbourne, C., Bramham, J., Polkey, C. E., David, A. S.

“…There is a burgeoning interest in the neural basis of the ability to attribute mental states to others; a capacity referred to as ‘theory of mind’ (ToM). We…”
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The evolution of epilepsy surgery by Polkey, CE

“…This review traces the evolution of epilepsy surgery from its early beginnings in the 20th century with the development of neurophysiology, and later the…”
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Long-term clinical and positron emission tomography outcome of fetal striatal transplantation in Huntington’s disease by Reuter, I, Tai, Y F, Pavese, N, Chaudhuri, K R, Mason, S, Polkey, C E, Clough, C, Brooks, D J, Barker, R A, Piccini, P

“…Two patients with moderate Huntington’s disease (HD) received bilateral fetal striatal allografts. One patient demonstrated, for the first time, increased…”
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Probabilistic learning and reversal deficits in patients with Parkinson’s disease or frontal or temporal lobe lesions: possible adverse effects of dopaminergic medication by Swainson, R., Rogers, R.D., Sahakian, B.J., Summers, B.A., Polkey, C.E., Robbins, T.W.

“…Three groups of patients with Parkinson’s disease (PD) — mild, unmedicated (UPD), mild, medicated (MPD) and severe, medicated (SPD) — and patients with lesions…”
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Is it worth pursuing surgery for epilepsy in patients with normal neuroimaging? by Alarcón, G, Valentín, A, Watt, C, Selway, R P, Lacruz, M E, Elwes, R D C, Jarosz, J M, Honavar, M, Brunhuber, F, Mullatti, N, Bodi, I, Salinas, M, Binnie, C D, Polkey, C E

“…Objective: To determine whether it is worth pursuing surgery for the treatment of epilepsy in patients with normal neuroimaging. Methods: Two patient…”
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Single-pulse electrical stimulation identifies epileptogenic frontal cortex in the human brain by VALENTIN, A, ALARCON, G, GARCIA-SEOANE, J. J, LACRUZ, M. E, NAYAK, S. D, HONAVAR, M, SELWAY, R. P, BINNIE, C. D, POLKEY, C. E

“…To assess the value of single-pulse electrical stimulation (SPES) to identify frontal epileptogenic cortex during presurgical assessment. SPES (1-millisecond…”
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Dissociating executive mechanisms of task control following frontal lobe damage and Parkinson's disease by ROGERS, R. D, SAHAKIAN, B. J, HODGES, J. R, POLKEY, C. E, KENNARD, C, ROBBINS, T. W

“…Twelve patients with focal damage of the frontal cortex and 12 patients with mild, medicated, early stage Parkinson's disease switched between letter- and…”
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Responses to single pulse electrical stimulation identify epileptogenesis in the human brain in vivo by Valentín, A., Anderson, M., Alarcón, G., Seoane, J. J. García, Selway, R., Binnie, C. D., Polkey, C. E.

“…The aim of the present study was to investigate in vivo cortical excitability in the human brain. We studied 45 consecutive patients with refractory epilepsy…”
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Social and emotional functioning following bilateral and unilateral neurosurgical prefrontal cortex lesions by Bramham, J., Morris, R. G., Hornak, J., Bullock, P., Polkey, C. E.

“…Alterations in emotional and social functioning such as impaired ability to recognize emotions in others, a lack of empathy and poor insight have commonly been…”
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Spatial memory deficits in patients with unilateral damage to the right hippocampal formation by Abrahams, S, Pickering, A, Polkey, C.E, Morris, R.G

“…Patients with unilateral temporal lobe damage resulting from intractable temporal lobe epilepsy (TLE, n=30) or from temporal lobe resection (temporal…”
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Predictors of outcome and pathological considerations in the surgical treatment of intractable epilepsy associated with temporal lobe lesions by Hennessy, M J, Elwes, R D C, Honavar, M, Rabe-Hesketh, S, Binnie, C D, Polkey, C E

“…OBJECTIVES To evaluate the influence of clinical, investigative, and pathological factors on seizure remission after temporal lobectomy for medically…”
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Histological heterogeneity of dysembryoplastic neuroepithelial tumour: identification and differential diagnosis in a series of 74 cases by HONAVAR, M, JANOTA, I, POLKEY, C. E

“…Aims In a retrospective study of resected specimens from 416 patients being treated for long‐standing epilepsy, 74 cases of dysembryoplastic neuroepithelial…”
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Neuropsychological effects associated with temporal lobectomy and amygdalohippocampectomy depending on Wada test failure by Lacruz, M E, Alarcón, G, Akanuma, N, Lum, F C K, Kissani, N, Koutroumanidis, M, Adachi, N, Binnie, C D, Polkey, C E, Morris, R G

“…Objective: To compare the neuropsychological effects of temporal lobectomy (TL) and amygdalohippocampectomy (AH), depending on whether the patients had passed…”
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Prognostic factors in presurgical assessment of frontal lobe epilepsy by Ferrier, C H, Engelsman, J, Alarcón, G, Binnie, C D, Polkey, C E

“…OBJECTIVES To determine predictors for surgical outcome in the presurgical assessment of frontal lobe epilepsy. METHODS Thirty seven patients were operated on…”
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Origin and propagation of interictal discharges in the acute electrocorticogram: Implications for pathophysiology and surgical treatment of temporal lobe epilepsy by ALARCON, G, GARCIA SEOANE, J. J, BINNIE, C. D, MARTIN MIGUEL, M. C, JULER, J, POLKEY, C. E, ELWES, R. D. C, ORTIZ BLASCO, J. M

“…Although acute electrocorticography (ECoG) is routinely performed during epilepsy surgery there is little evidence that the extent of the discharging regions…”
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Differential spatial memory impairment after right temporal lobectomy demonstrated using temporal titration by NUNN, J. A, GRAYDON, F. J. X, POLKEY, C. E, MORRIS, R. G

“…In this study a temporal titration method to explore the extent to which spatial memory is differentially impaired following right temporal lobectomy was…”
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Schizophrenia-like psychosis arising de novo following a temporal lobectomy: timing and risk factors by Shaw, P, Mellers, J, Henderson, M, Polkey, C, David, A S, Toone, B K

“…Objectives: To clarify risk factors for the development of schizophrenia-like psychotic disorders following temporal lobectomy, and to explore the possibility…”
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Impaired dimensional selection but intact use of reward feedback during visual discrimination learning in Parkinson's disease by Swainson, R., SenGupta, D., Shetty, T., Watkins, L.H.A., Summers, B.A., Sahakian, B.J., Polkey, C.E., Barker, R.A., Robbins, T.W.

“…It has been suggested that Parkinson's disease (PD) impairs the ability to learn on the basis of reward or reinforcing feedback i.e., by trial-and-error. In…”
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