Search Results - "POGNONEC, Philippe"
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Quantitative phase microscopy for non-invasive live cell population monitoring
Published in Scientific reports (24-02-2021)“…We present here a label-free development based on preexisting Quantitative Phase Imaging (QPI) that allows non-invasive live monitoring of both individual…”
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ERK and cell death: cadmium toxicity, sustained ERK activation and cell death
Published in The FEBS journal (01-01-2010)“…Extracellular signal-related kinase (ERK) is a key player in cell signaling. After 25 years of investigation, ERK has been associated with every major aspect…”
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A novel function for fragile X mental retardation protein in translational activation
Published in PLoS biology (01-01-2009)“…Fragile X syndrome, the most frequent form of inherited mental retardation, is due to the absence of Fragile X Mental Retardation Protein (FMRP), an…”
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Deletion of a Single Allele of the Dkk1 Gene Leads to an Increase in Bone Formation and Bone Mass
Published in Journal of bone and mineral research (01-06-2006)“…Wnt/β‐catenin signaling has been proven to play a central role in bone biology. Unexpectedly, the Wnt antagonist Dkk2 is required for terminal osteoblast…”
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A caspase 8-based suicide switch induces apoptosis in nanobody-directed chimeric receptor expressing T cells
Published in International journal of hematology (01-04-2012)“…In accordance with the two-step hypothesis of T cell activation and the observation that stimulation through the T cell receptor (TCR) alone may lead to…”
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Lentiviral Vectors Efficiently Transduce Quiescent Mature 3T3-L1 Adipocytes
Published in Molecular therapy (01-02-2004)“…Obesity is associated with many serious afflictions such as cardiovascular disease, cancer, and diabetes. One of the main cellular systems used to study the…”
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Non Invasive Live Cell Cycle Monitoring using Quantitative Phase Imaging and Proximal Machine Learning Methods
Published in 2019 IEEE 32nd International Symposium on Computer-Based Medical Systems (CBMS) (01-06-2019)“…This interdisciplinary work focuses on the interest of a new proximal algorithm (ADRS ) for supervised classification of live cell populations growing in a…”
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Conference Proceeding -
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Long-term extracellular signal-related kinase activation following cadmium intoxication is negatively regulated by a protein kinase C-dependent pathway affecting cadmium transport
Published in The FEBS journal (01-03-2009)“…Extracellular signal-related kinase (ERK) is a well-known kinase taking part in a signal transduction cascade in response to extracellular stimuli. ERK is…”
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Manganese is highly effective in protecting cells from cadmium intoxication
Published in Biochemical and biophysical research communications (08-12-2006)“…Cadmium poisoning results in cell death. Although several intracellular pathways have been identified in this response, transport systems responsible for…”
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Development of a new bicistronic retroviral vector with strong IRES activity
Published in BMC biotechnology (12-01-2006)“…Internal Ribosome Entry Site (IRES)-based bicistronic vectors are important tools in today's cell biology. Among applications, the expression of two proteins…”
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A new generation of pPRIG-based retroviral vectors
Published in BMC biotechnology (30-11-2007)“…Retroviral vectors are valuable tools for gene transfer. Particularly convenient are IRES-containing retroviral vectors expressing both the protein of interest…”
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Development of an inducible suicide gene system based on human caspase 8
Published in Cancer gene therapy (01-07-2005)“…Suicide gene-therapy strategies are promising approaches in treating various diseases such as cancers, atherosclerosis, and graft-versus-host-disease. Here, we…”
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The Role of the Ets2 Transcription Factor in the Proliferation, Maturation, and Survival of Mouse Thymocytes
Published in The Journal of immunology (1950) (01-11-2002)“…In this study, we investigated the effects of Ets2 expression on the proliferation, maturation, and survival of thymocytes by establishing transgenic mice that…”
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REtools: a laboratory program for restriction enzyme work: enzyme selection and reaction condition assistance
Published in BMC bioinformatics (28-02-2006)“…Restriction enzymes are one of the everyday tools used in molecular biology. The continuously expanding panel of known restriction enzymes (several thousands)…”
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Bcl-xL Expression Correlates with Primary Macrophage Differentiation, Activation of Functional Competence, and Survival and Results from Synergistic Transcriptional Activation by Ets2 and PU.1
Published in The Journal of biological chemistry (25-05-2001)“…Depriving primary bone marrow-derived macrophages of colony-stimulating factor-1 (CSF-1) induces programmed cell death by apoptosis. We show that cell death is…”
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ERK and cell death: overview
Published in The FEBS journal (01-01-2010)Get full text
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Cross-family interaction between the bHLHZip USF and bZip Fra1 proteins results in down-regulation of AP1 activity
Published in Oncogene (01-05-1997)“…Heterodimerization among the basic-leucine zipper (bZIP) proteins or among the basic-helix-loop-helix-leucine zipper (bHLHZip) proteins confers a multitude of…”
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Mitotic Index Determination on Live Cells From Label-Free Acquired Quantitative Phase Images Using a Supervised Autoencoder
Published in IEEE/ACM transactions on computational biology and bioinformatics (01-11-2021)“…This interdisciplinary work focuses on the interest of a new auto-encoder for supervised classification of live cell populations growing in a thermostated…”
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Virtual nitrogen tank to monitor frozen cell stocks
Published in BioTechniques (01-07-2000)“…We developed a program to facilitate the monitoring of biological samples (cell lines, sera, etc.) that are stored in liquid nitrogen containers. The program…”
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A systematic evaluation of sorting motifs in the sodium-iodide symporter (NIS)
Published in Biochemical journal (01-04-2016)“…The sodium-iodide symporter (NIS) is an integral membrane protein that plays a crucial role in iodide accumulation, especially in the thyroid. As for many…”
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