Search Results - "PLoS pathogens"

One Health: A new definition for a sustainable and healthy future by Adisasmito, Wiku B, Almuhairi, Salama, Behravesh, Casey Barton, Bilivogui, Pépé, Bukachi, Salome A, Casas, Natalia, Cediel Becerra, Natalia, Charron, Dominique F, Chaudhary, Abhishek, Ciacci Zanella, Janice R, Cunningham, Andrew A, Dar, Osman, Debnath, Nitish, Dungu, Baptiste, Farag, Elmoubasher, Gao, George F, Hayman, David T S, Khaitsa, Margaret, Koopmans, Marion P G, Machalaba, Catherine, Mackenzie, John S, Markotter, Wanda, Mettenleiter, Thomas C, Morand, Serge, Smolenskiy, Vyacheslav, Zhou, Lei

“…Following a proposal made by the French and German Ministers for Foreign Affairs at the November 2020 Paris Peace Forum, 4 global partners, the Food and…”
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Interplay between SARS-CoV-2 and the type I interferon response by Sa Ribero, Margarida, Jouvenet, Nolwenn, Dreux, Marlène, Nisole, Sébastien

“…The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is responsible for the current COVID-19 pandemic. An unbalanced immune response, characterized…”
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Cryo-EM structure of the SARS coronavirus spike glycoprotein in complex with its host cell receptor ACE2 by Song, Wenfei, Gui, Miao, Wang, Xinquan, Xiang, Ye

“…The trimeric SARS coronavirus (SARS-CoV) surface spike (S) glycoprotein consisting of three S1-S2 heterodimers binds the cellular receptor…”
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The hallmarks of COVID-19 disease by Tang, Daolin, Comish, Paul, Kang, Rui

“…Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a novel coronavirus that has caused a worldwide pandemic of the human respiratory illness…”
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Discovery of a rich gene pool of bat SARS-related coronaviruses provides new insights into the origin of SARS coronavirus by Hu, Ben, Zeng, Lei-Ping, Yang, Xing-Lou, Ge, Xing-Yi, Zhang, Wei, Li, Bei, Xie, Jia-Zheng, Shen, Xu-Rui, Zhang, Yun-Zhi, Wang, Ning, Luo, Dong-Sheng, Zheng, Xiao-Shuang, Wang, Mei-Niang, Daszak, Peter, Wang, Lin-Fa, Cui, Jie, Shi, Zheng-Li

“…A large number of SARS-related coronaviruses (SARSr-CoV) have been detected in horseshoe bats since 2005 in different areas of China. However, these bat…”
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Are pangolins the intermediate host of the 2019 novel coronavirus (SARS-CoV-2)? by Liu, Ping, Jiang, Jing-Zhe, Wan, Xiu-Feng, Hua, Yan, Li, Linmiao, Zhou, Jiabin, Wang, Xiaohu, Hou, Fanghui, Chen, Jing, Zou, Jiejian, Chen, Jinping

“…The outbreak of a novel corona Virus Disease 2019 (COVID-19) in the city of Wuhan, China has resulted in more than 1.7 million laboratory confirmed cases all…”
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Furin cleavage of SARS-CoV-2 Spike promotes but is not essential for infection and cell-cell fusion by Papa, Guido, Mallery, Donna L, Albecka, Anna, Welch, Lawrence G, Cattin-Ortolá, Jérôme, Luptak, Jakub, Paul, David, McMahon, Harvey T, Goodfellow, Ian G, Carter, Andrew, Munro, Sean, James, Leo C

“…Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) infects cells by binding to the host cell receptor ACE2 and undergoing virus-host membrane fusion…”
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Sex-specific clinical characteristics and prognosis of coronavirus disease-19 infection in Wuhan, China: A retrospective study of 168 severe patients by Meng, Yifan, Wu, Ping, Lu, Wanrong, Liu, Kui, Ma, Ke, Huang, Liang, Cai, Jiaojiao, Zhang, Hong, Qin, Yu, Sun, Haiying, Ding, Wencheng, Gui, Lingli, Wu, Peng

“…To confirm the relationship between sex and the progression of Coronavirus Disease-19 (COVID-19), and its potential mechanism, among severe patients. For this…”
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From bacterial killing to immune modulation: Recent insights into the functions of lysozyme by Ragland, Stephanie A, Criss, Alison K

“…Lysozyme is a cornerstone of innate immunity. The canonical mechanism for bacterial killing by lysozyme occurs through the hydrolysis of cell wall…”
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K18-hACE2 mice develop respiratory disease resembling severe COVID-19 by Yinda, Claude Kwe, Port, Julia R, Bushmaker, Trenton, Offei Owusu, Irene, Purushotham, Jyothi N, Avanzato, Victoria A, Fischer, Robert J, Schulz, Jonathan E, Holbrook, Myndi G, Hebner, Madison J, Rosenke, Rebecca, Thomas, Tina, Marzi, Andrea, Best, Sonja M, de Wit, Emmie, Shaia, Carl, van Doremalen, Neeltje, Munster, Vincent J

“…SARS-CoV-2 emerged in late 2019 and resulted in the ongoing COVID-19 pandemic. Several animal models have been rapidly developed that recapitulate the…”
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Lipid droplets fuel SARS-CoV-2 replication and production of inflammatory mediators by Dias, Suelen Silva Gomes, Soares, Vinicius Cardoso, Ferreira, André C, Sacramento, Carolina Q, Fintelman-Rodrigues, Natalia, Temerozo, Jairo R, Teixeira, Lívia, Nunes da Silva, Marcos Alexandre, Barreto, Ester, Mattos, Mayara, de Freitas, Caroline S, Azevedo-Quintanilha, Isaclaudia G, Manso, Pedro Paulo A, Miranda, Milene D, Siqueira, Marilda Mendonça, Hottz, Eugenio D, Pão, Camila R R, Bou-Habib, Dumith C, Barreto-Vieira, Debora F, Bozza, Fernando A, Souza, Thiago M L, Bozza, Patricia T

“…Viruses are obligate intracellular parasites that make use of the host metabolic machineries to meet their biosynthetic needs. Thus, identifying the host…”
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Candida auris: A rapidly emerging cause of hospital-acquired multidrug-resistant fungal infections globally by Chowdhary, Anuradha, Sharma, Cheshta, Meis, Jacques F

“…About the Authors: Anuradha Chowdhary * E-mail: dranuradha@hotmail.com Affiliation: Department of Medical Mycology, Vallabhbhai Patel Chest Institute,…”
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Structural basis of RNA recognition by the SARS-CoV-2 nucleocapsid phosphoprotein by Dinesh, Dhurvas Chandrasekaran, Chalupska, Dominika, Silhan, Jan, Koutna, Eliska, Nencka, Radim, Veverka, Vaclav, Boura, Evzen

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of the coronavirus disease 2019 (COVID-19). SARS-CoV-2 is a single-stranded…”
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Biological sex impacts COVID-19 outcomes by Klein, Sabra L, Dhakal, Santosh, Ursin, Rebecca L, Deshpande, Sharvari, Sandberg, Kathryn, Mauvais-Jarvis, Franck

“…The current novel coronavirus disease 2019 (COVID-19) pandemic is revealing profound differences between men and women in disease outcomes worldwide. In the…”
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Climate change and the emergence of fungal pathogens by Nnadi, Nnaemeka Emmanuel, Carter, Dee A

“…Climate change, defined by the United Nations Framework Convention on Climate Change as “a change of climate which is attributed directly or indirectly to…”
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Interferon regulatory factor 1 (IRF1) and anti-pathogen innate immune responses by Feng, Hui, Zhang, Yi-Bing, Gui, Jian-Fang, Lemon, Stanley M, Yamane, Daisuke

“…The eponymous member of the interferon regulatory factor (IRF) family, IRF1, was originally identified as a nuclear factor that binds and activates the…”
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Development and evaluation of a rapid CRISPR-based diagnostic for COVID-19 by Hou, Tieying, Zeng, Weiqi, Yang, Minling, Chen, Wenjing, Ren, Lili, Ai, Jingwen, Wu, Ji, Liao, Yalong, Gou, Xuejing, Li, Yongjun, Wang, Xiaorui, Su, Hang, Gu, Bing, Wang, Jianwei, Xu, Teng

“…The recent outbreak of human infections caused by SARS-CoV-2, the third zoonotic coronavirus has raised great public health concern globally. Rapid and…”
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On the whereabouts of SARS-CoV-2 in the human body: A systematic review by Trypsteen, Wim, Van Cleemput, Jolien, Snippenberg, Willem van, Gerlo, Sarah, Vandekerckhove, Linos

“…Since SARS-CoV-2 appeared in the human population, the scientific community has scrambled to gather as much information as possible to find good strategies for…”
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Microbiota-host communications: Bacterial extracellular vesicles as a common language by Ñahui Palomino, Rogers A, Vanpouille, Christophe, Costantini, Paolo E, Margolis, Leonid

“…Both gram-negative and gram-positive bacteria release extracellular vesicles (EVs) that contain components from their mother cells. Bacterial EVs are similar…”
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The coronavirus proofreading exoribonuclease mediates extensive viral recombination by Gribble, Jennifer, Stevens, Laura J, Agostini, Maria L, Anderson-Daniels, Jordan, Chappell, James D, Lu, Xiaotao, Pruijssers, Andrea J, Routh, Andrew L, Denison, Mark R

“…Recombination is proposed to be critical for coronavirus (CoV) diversity and emergence of SARS-CoV-2 and other zoonotic CoVs. While RNA recombination is…”
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