Search Results - "PLoS biology"

The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research by Percie du Sert, Nathalie, Hurst, Viki, Ahluwalia, Amrita, Alam, Sabina, Avey, Marc T, Baker, Monya, Browne, William J, Clark, Alejandra, Cuthill, Innes C, Dirnagl, Ulrich, Emerson, Michael, Garner, Paul, Holgate, Stephen T, Howells, David W, Karp, Natasha A, Lazic, Stanley E, Lidster, Katie, MacCallum, Catriona J, Macleod, Malcolm, Pearl, Esther J, Petersen, Ole H, Rawle, Frances, Reynolds, Penny, Rooney, Kieron, Sena, Emily S, Silberberg, Shai D, Steckler, Thomas, Würbel, Hanno

“…Reproducible science requires transparent reporting. The ARRIVE guidelines (Animal Research: Reporting of In Vivo Experiments) were originally developed in…”
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Reporting animal research: Explanation and elaboration for the ARRIVE guidelines 2.0 by Percie du Sert, Nathalie, Ahluwalia, Amrita, Alam, Sabina, Avey, Marc T, Baker, Monya, Browne, William J, Clark, Alejandra, Cuthill, Innes C, Dirnagl, Ulrich, Emerson, Michael, Garner, Paul, Holgate, Stephen T, Howells, David W, Hurst, Viki, Karp, Natasha A, Lazic, Stanley E, Lidster, Katie, MacCallum, Catriona J, Macleod, Malcolm, Pearl, Esther J, Petersen, Ole H, Rawle, Frances, Reynolds, Penny, Rooney, Kieron, Sena, Emily S, Silberberg, Shai D, Steckler, Thomas, Würbel, Hanno

“…Improving the reproducibility of biomedical research is a major challenge. Transparent and accurate reporting is vital to this process; it allows readers to…”
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A proteomic atlas of senescence-associated secretomes for aging biomarker development by Basisty, Nathan, Kale, Abhijit, Jeon, Ok Hee, Kuehnemann, Chisaka, Payne, Therese, Rao, Chirag, Holtz, Anja, Shah, Samah, Sharma, Vagisha, Ferrucci, Luigi, Campisi, Judith, Schilling, Birgit

“…The senescence-associated secretory phenotype (SASP) has recently emerged as a driver of and promising therapeutic target for multiple age-related conditions,…”
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Inferring the mammal tree: Species-level sets of phylogenies for questions in ecology, evolution, and conservation by Upham, Nathan S, Esselstyn, Jacob A, Jetz, Walter

“…Big, time-scaled phylogenies are fundamental to connecting evolutionary processes to modern biodiversity patterns. Yet inferring reliable phylogenetic trees…”
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CellProfiler 3.0: Next-generation image processing for biology by McQuin, Claire, Goodman, Allen, Chernyshev, Vasiliy, Kamentsky, Lee, Cimini, Beth A, Karhohs, Kyle W, Doan, Minh, Ding, Liya, Rafelski, Susanne M, Thirstrup, Derek, Wiegraebe, Winfried, Singh, Shantanu, Becker, Tim, Caicedo, Juan C, Carpenter, Anne E

“…CellProfiler has enabled the scientific research community to create flexible, modular image analysis pipelines since its release in 2005. Here, we describe…”
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Revised Estimates for the Number of Human and Bacteria Cells in the Body by Sender, Ron, Fuchs, Shai, Milo, Ron

“…Reported values in the literature on the number of cells in the body differ by orders of magnitude and are very seldom supported by any measurements or…”
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Recommendations for daytime, evening, and nighttime indoor light exposure to best support physiology, sleep, and wakefulness in healthy adults by Brown, Timothy M, Brainard, George C, Cajochen, Christian, Czeisler, Charles A, Hanifin, John P, Lockley, Steven W, Lucas, Robert J, Münch, Mirjam, O'Hagan, John B, Peirson, Stuart N, Price, Luke L A, Roenneberg, Till, Schlangen, Luc J M, Skene, Debra J, Spitschan, Manuel, Vetter, Céline, Zee, Phyllis C, Wright, Jr, Kenneth P

“…Ocular light exposure has important influences on human health and well-being through modulation of circadian rhythms and sleep, as well as neuroendocrine and…”
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A unifying structural and functional model of the coronavirus replication organelle: Tracking down RNA synthesis by Snijder, Eric J, Limpens, Ronald W A L, de Wilde, Adriaan H, de Jong, Anja W M, Zevenhoven-Dobbe, Jessika C, Maier, Helena J, Faas, Frank F G A, Koster, Abraham J, Bárcena, Montserrat

“…Zoonotic coronavirus (CoV) infections, such as those responsible for the current severe acute respiratory syndrome-CoV 2 (SARS-CoV-2) pandemic, cause grave…”
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Microplastic effects on carbon cycling processes in soils by Rillig, Matthias C, Leifheit, Eva, Lehmann, Johannes

“…Microplastics (MPs), plastic particles <5 mm, are found in environments, including terrestrial ecosystems, planetwide. Most research so far has focused on…”
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The biology of extracellular vesicles: The known unknowns by Margolis, Leonid, Sadovsky, Yoel

“…For many years, double-layer phospholipid membrane vesicles, released by most cells, were not considered to be of biological significance. This stance has…”
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The gender gap in science: How long until women are equally represented? by Holman, Luke, Stuart-Fox, Devi, Hauser, Cindy E

“…Women comprise a minority of the Science, Technology, Engineering, Mathematics, and Medicine (STEMM) workforce. Quantifying the gender gap may identify fields…”
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Why are RNA virus mutation rates so damn high? by Duffy, Siobain

“…The high mutation rate of RNA viruses is credited with their evolvability and virulence. This Primer, however, discusses recent evidence that this is, in part,…”
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Urgent need for a non-discriminatory and non-stigmatizing nomenclature for monkeypox virus by Happi, Christian, Adetifa, Ifedayo, Mbala, Placide, Njouom, Richard, Nakoune, Emmanuel, Happi, Anise, Ndodo, Nnaemeka, Ayansola, Oyeronke, Mboowa, Gerald, Bedford, Trevor, Neher, Richard A, Roemer, Cornelius, Hodcroft, Emma, Tegally, Houriiyah, O'Toole, Áine, Rambaut, Andrew, Pybus, Oliver, Kraemer, Moritz U G, Wilkinson, Eduan, Isidro, Joana, Borges, Vítor, Pinto, Miguel, Gomes, João Paulo, Freitas, Lucas, Resende, Paola C, Lee, Raphael T C, Maurer-Stroh, Sebastian, Baxter, Cheryl, Lessells, Richard, Ogwell, Ahmed E, Kebede, Yenew, Tessema, Sofonias K, de Oliveira, Tulio

“…We propose a novel, non-discriminatory classification of monkeypox virus diversity. Together with the World Health Organization, we named three clades (I, IIa…”
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ClipKIT: A multiple sequence alignment trimming software for accurate phylogenomic inference by Steenwyk, Jacob L, Buida, 3rd, Thomas J, Li, Yuanning, Shen, Xing-Xing, Rokas, Antonis

“…Highly divergent sites in multiple sequence alignments (MSAs), which can stem from erroneous inference of homology and saturation of substitutions, are thought…”
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Open science challenges, benefits and tips in early career and beyond by Allen, Christopher, Mehler, David M A

“…The movement towards open science is a consequence of seemingly pervasive failures to replicate previous research. This transition comes with great benefits…”
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The manifold costs of being a non-native English speaker in science by Amano, Tatsuya, Ramírez-Castañeda, Valeria, Berdejo-Espinola, Violeta, Borokini, Israel, Chowdhury, Shawan, Golivets, Marina, González-Trujillo, Juan David, Montaño-Centellas, Flavia, Paudel, Kumar, White, Rachel Louise, Veríssimo, Diogo

“…The use of English as the common language of science represents a major impediment to maximising the contribution of non-native English speakers to science…”
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Microstructural and functional gradients are increasingly dissociated in transmodal cortices by Paquola, Casey, Vos De Wael, Reinder, Wagstyl, Konrad, Bethlehem, Richard A I, Hong, Seok-Jun, Seidlitz, Jakob, Bullmore, Edward T, Evans, Alan C, Misic, Bratislav, Margulies, Daniel S, Smallwood, Jonathan, Bernhardt, Boris C

“…While the role of cortical microstructure in organising neural function is well established, it remains unclear how structural constraints can give rise to…”
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Research priorities for harnessing plant microbiomes in sustainable agriculture by Busby, Posy E, Soman, Chinmay, Wagner, Maggie R, Friesen, Maren L, Kremer, James, Bennett, Alison, Morsy, Mustafa, Eisen, Jonathan A, Leach, Jan E, Dangl, Jeffery L

“…Feeding a growing world population amidst climate change requires optimizing the reliability, resource use, and environmental impacts of food production. One…”
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The Hong Kong Principles for assessing researchers: Fostering research integrity by Moher, David, Bouter, Lex, Kleinert, Sabine, Glasziou, Paul, Sham, Mai Har, Barbour, Virginia, Coriat, Anne-Marie, Foeger, Nicole, Dirnagl, Ulrich

“…For knowledge to benefit research and society, it must be trustworthy. Trustworthy research is robust, rigorous, and transparent at all stages of design,…”
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In vivo antiviral host transcriptional response to SARS-CoV-2 by viral load, sex, and age by Lieberman, Nicole A P, Peddu, Vikas, Xie, Hong, Shrestha, Lasata, Huang, Meei-Li, Mears, Megan C, Cajimat, Maria N, Bente, Dennis A, Shi, Pei-Yong, Bovier, Francesca, Roychoudhury, Pavitra, Jerome, Keith R, Moscona, Anne, Porotto, Matteo, Greninger, Alexander L

“…Despite limited genomic diversity, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has shown a wide range of clinical manifestations in different…”
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