Search Results - "PLOWMAN, G. D"

Transgenic expression of the human amphiregulin gene induces a psoriasis-like phenotype by Cook, P W, Piepkorn, M, Clegg, C H, Plowman, G D, DeMay, J M, Brown, J R, Pittelkow, M R

“…Amphiregulin (AR) is a heparin-binding, heparin-inhibited member of the epidermal growth factor (EGF) family and an autocrine growth factor for human…”
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The cellular response to neuregulins is governed by complex interactions of the erbB receptor family by Riese, David J., van Raaij, Tom M., Plowman, Gregory D., Andrews, Glenn C., Stern, David F.

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The amphiregulin gene encodes a novel epidermal growth factor-related protein with tumor-inhibitory activity by PLOWMAN, G. D, GREEN, J. M, MCDONALD, V. L, NEUBAUER, M. G, DISTECHE, C. M, TODARO, G. J, SHOYAB, M

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Molecular Cloning and Expression of an Additional Epidermal Growth Factor Receptor-Related Gene by Plowman, Gregory D., Whitney, Gena S., Neubauer, Michael G., Green, Janell M., McDonald, Vicki L., Todaro, George J., Shoyab, Mohammed

“…Epidermal growth factor (EGF), transforming growth factor α (TGF-α), and amphiregulin are structurally and functionally related growth regulatory proteins…”
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Expression of Betacellulin and Epiregulin Genes in the Mouse Uterus Temporally by the Blastocyst Solely at the Site of Its Apposition Is Coincident with the “Window” of Implantation by Das, S.K., Das, N., Wang, J., Lim, H., Schryver, B., Plowman, G.D., Dey, S.K.

“…In the mouse, the process of implantation is initiated by the attachment reaction between the blastocyst trophectoderm and uterine luminal epithelium that…”
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Receptor tyrosine kinases as targets for inhibition of angiogenesis by Shawver, Laura K., Lipson, Kenneth E., Annie T. Fong, T., McMahon, Gerald, Plowman, Greg D., Strawn, Laurie M.

“…Anti-angiogenic agents potentially have broad applications in the clinic. Although most agents now in development are intended ultimately for use as…”
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Expression of the c-erbB-3 protein in normal human adult and fetal tissues by Prigent, S A, Lemoine, N R, Hughes, C M, Plowman, G D, Selden, C, Gullick, W J

“…c-erbB-3 is a member of the type I family of growth factor receptors which includes the epidermal growth factor (EGF) receptor and c-erbB-2. Whereas for EGF…”
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Differential Expression of Epidermal Growth Factor-Related Proteins in Human Colorectal Tumors by CIARDIELLO, F, KIM, N, SAEKI, T, DONO, R, GRAZIELLA PERSICO, M, PLOWMAN, G. D, GARRIGUES, J, RADKE, S, TODARO, G. J, SALOMON, D. S

“…Amphiregulin (AR) and cripto are proteins that are structurally related to epidermal growth factor (EGF) and transforming growth factor α (TGF-α). AR is also…”
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Interleukin 1α and Tumor Necrosis Factor α Stimulate Autocrine Amphiregulin Expression and Proliferation of Human Papillomavirus-Immortalized and Carcinoma-Derived Cervical Epithelial Cells by Woodworth, Craig D., McMullin, Erin, Iglesias, Maite, Plowman, Gregory D.

“…Infection with multiple sexually transmitted agents has been associated with inflammation of the cervix and an increased risk of cervical cancer in women…”
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Interleukin-6 and interleukin-6 soluble receptor regulate proliferation of normal, human papillomavirus-immortalized, and carcinoma-derived cervical cells in vitro by Iglesias, M, Plowman, GD, Woodworth, CD

“…A variety of sexually transmitted diseases frequently accompany infection with human papillomavirus and stimulate inflammation of the cervical mucosa…”
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A heparin sulfate-regulated human keratinocyte autocrine factor is similar or identical to amphiregulin by COOK, P. W, MATTOX, P. A, KEEBLE, W. W, PITTELKOW, M. R, PLOWMAN, G. D, MOHAMMED SHOYAB, ADELMAN, J. P, SHIPLEY, G. D

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cDNA cloning and sequence analysis of beta ig-h3, a novel gene induced in a human adenocarcinoma cell line after treatment with transforming growth factor-beta by Skonier, J, Neubauer, M, Madisen, L, Bennett, K, Plowman, G D, Purchio, A F

“…Transforming growth factor-beta (TGF-beta) is capable of affecting the proliferation of many cell types. To identify novel genes whose protein products may…”
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Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions by Lev, S, Moreno, H, Martinez, R, Canoll, P, Peles, E, Musacchio, J M, Plowman, G D, Rudy, B, Schlessinger, J

“…The protein tyrosine kinase PYK2, which is highly expressed in the central nervous system, is rapidly phosphorylated on tyrosine residues in response to…”
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The epithelin precursor encodes two proteins with opposing activities on epithelial cell growth by PLOWMAN, G. D, GREEN, J. M, NEUBAUER, M. G, BUCKLEY, S. D, MCDONALD, V. L, TODARO, G. J, SHOYAB, M

“…Epithelin 1 and 2 were originally purified from rat kidneys based on their ability to inhibit the growth of A-431 human epidermoid carcinoma cells (Shoyab, M.,…”
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Structure and Function of Human Amphiregulin: A Member of the Epidermal Growth Factor Family by Shoyab, Mohammed, Plowman, Gregory D., McDonald, Vicki L., Bradley, J. Garrett, Todaro, George J.

“…The complete amino acid sequence of amphiregulin, a bifunctional cell growth modulator, was determined. The truncated form contains 78 amino acids, whereas a…”
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The heparin-binding domain of amphiregulin necessitates the precursor pro-region for growth factor secretion by ETHORNE, B. A, PLOWMAN, G. D

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Epithelins 1 and 2: Isolation and Characterization of Two Cysteine-Rich Growth-Modulating Proteins by Shoyab, Mohammed, McDonald, Vicki L., Byles, Christine, Todaro, George J., Plowman, Gregory D.

“…Two proteins, termed epithelin 1 and epithelin 2, that inhibit the growth of A431 cells, derived from a human epidermal carcinoma of the vulva, have been…”
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Protein tyrosine kinase PYK2 involved in Ca2+-induced regulation of ion channel and MAP kinase functions by Lev, S, Moreno, H, Martinez, R, Canoll, P, Peles, E, Musacchio, J M, Plowman, G D, Rudy, B, Schlessinger, J

“…The protein tyrosine kinase PYK2, which is highly expressed in the central nervous system, is rapidly phosphorylated on tyrosine residues in response to…”
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The protein kinases of budding yeast: six score and more by Hunter, Tony, Plowman, Gregory D.

“…The completion of the budding yeast genome sequencing project has made it possible to determine not only the total number of genes, but also the exact number…”
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A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers by Bischoff, James R., Anderson, Lee, Zhu, Yingfang, Mossie, Kevin, Ng, Lelia, Souza, Brian, Schryver, Brian, Flanagan, Peter, Clairvoyant, Felix, Ginther, Charles, Chan, Clarence S.M., Novotny, Mike, Slamon, Dennis J., Plowman, Gregory D.

“…Genetic and biochemical studies in lower eukaryotes have identified several proteins that ensure accurate segregation of chromosomes. These include the…”
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