Search Results - "PLEASURE, D"

Stress and glucocorticoids promote oligodendrogenesis in the adult hippocampus by Chetty, S, Friedman, A R, Taravosh-Lahn, K, Kirby, E D, Mirescu, C, Guo, F, Krupik, D, Nicholas, A, Geraghty, A C, Krishnamurthy, A, Tsai, M-K, Covarrubias, D, Wong, A T, Francis, D D, Sapolsky, R M, Palmer, T D, Pleasure, D, Kaufer, D

“…Stress can exert long-lasting changes on the brain that contribute to vulnerability to mental illness, yet mechanisms underlying this long-term vulnerability…”
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A Smoothened receptor agonist is neuroprotective and promotes regeneration after ischemic brain injury by Chechneva, O V, Mayrhofer, F, Daugherty, D J, Krishnamurty, R G, Bannerman, P, Pleasure, D E, Deng, W

“…Ischemic stroke occurs as a result of blood supply interruption to the brain causing tissue degeneration, patient disabilities or death. Currently, treatment…”
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The neuronal metabolite NAA regulates histone H3 methylation in oligodendrocytes and myelin lipid composition by Singhal, N. K., Huang, H., Li, S., Clements, R., Gadd, J., Daniels, A., Kooijman, E. E., Bannerman, P., Burns, T., Guo, F., Pleasure, D., Freeman, E., Shriver, L., McDonough, J.

“…The neuronal mitochondrial metabolite N -acetylaspartate (NAA) is decreased in the multiple sclerosis (MS) brain. NAA is synthesized in neurons by the enzyme N…”
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Olig2/Plp-positive progenitor cells give rise to Bergmann glia in the cerebellum by Chung, S-H, Guo, F, Jiang, P, Pleasure, D E, Deng, W

“…NG2 (nerve/glial antigen2)-expressing cells represent the largest population of postnatal progenitors in the central nervous system and have been classified as…”
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Motor neuron pathology in experimental autoimmune encephalomyelitis: studies in THY1-YFP transgenic mice by Bannerman, P. G., Hahn, A., Ramirez, S., Morley, M., Bönnemann, C., Yu, S., Zhang, G.-X., Rostami, A., Pleasure, D.

“…Using adult male C57BL/6 mice that express a yellow fluorescent protein transgene in their motor neurons, we induced experimental autoimmune encephalomyelitis…”
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ZPK/DLK and MKK4 form the critical gateway to axotomy-induced motoneuron death in neonates by Itoh, Takayuki, Horiuchi, Makoto, Ikeda, Jr, Raymond H, Xu, Jie, Bannerman, Peter, Pleasure, David, Penninger, Josef M, Tournier, Cathy, Itoh, Aki

“…Motoneuron death after transection of the axons (axotomy) in neonates is believed to share the same mechanistic bases as naturally occurring programmed cell…”
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The p38α mitogen-activated protein kinase is a key regulator of myelination and remyelination in the CNS by Chung, S-H, Biswas, S, Selvaraj, V, Liu, X-B, Sohn, J, Jiang, P, Chen, C, Chmilewsky, F, Marzban, H, Horiuchi, M, Pleasure, D E, Deng, W

“…The p38 α mitogen-activated protein kinase (MAPK) is one of the serine/threonine kinases regulating a variety of biological processes, including cell-type…”
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Induction of apoptosis by La Crosse virus infection and role of neuronal differentiation and human bcl-2 expression in its prevention by Pekosz, A, Phillips, J, Pleasure, D, Merry, D, Gonzalez-Scarano, F

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Acute and chronic alterations in calcium homeostasis in 3-nitropropionic acid-treated human NT2-N neurons by Lee, W.-T, Itoh, T, Pleasure, D

“…3-Nitropropionic acid (3-NP), an irreversible inhibitor of succinate dehydrogenase, induced ATP depletion and both necrosis and apoptosis in human NT2-N…”
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Non- N-methyl- d-aspartate glutamate receptors mediate oxygen–glucose deprivation-induced oligodendroglial injury by Yoshioka, Akira, Yamaya, Yoko, Saiki, Shinji, Kanemoto, Masumi, Hirose, Genjiro, Beesley, Jacqueline, Pleasure, David

“…Cells of oligodendroglial lineage are susceptible to oxygen and glucose deprivation. When oligodendrocyte-like cells differentiated from CG-4-immortalized rat…”
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Opposing Contributions of NR1 and NR2 to Protein Kinase C Modulation of NMDA Receptors by Grant, Elfrida R., Bacskai, Brian J., Anegawa, Norifusa J., Pleasure, David E., Lynch, David R.

“…: N‐Methyl‐d‐aspartate (NMDA) receptors mediate increases in intracellular calcium that can be modulated by protein kinase C (PKC). As PKC modulation of NMDA…”
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Schwann cell-autonomous role of neuropilin-2 by Ara, J., Bannerman, P., Shaheen, F., Pleasure, D.E.

“…Neuropilins and group A plexins are components of receptor complexes for class 3 semaphorins, gradients of which help to guide migration of neural progenitor…”
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Inducible Expression of Neuronal Glutamate Receptor Channels in the NT2 Human Cell Line by Younkin, Donald P., Tang, Cha-Min, Hardy, Mattie, Reddy, Usha R., Shi, Qing-Yao, Pleasure, Samuel J., Virginia M.-Y. Lee, Pleasure, David

“…Glutamate receptor (GluR) channels are responsible for a number of fundamental properties of the mammalian central nervous system, including nearly all…”
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ECK, a human EPH-related gene, maps to 1p36.1, a common region of alteration in human cancers by SULMAN, E. P, TANG, X. X, ALLEN, C, BIEGEL, J. A, PLEASURE, D. E, BRODEUR, G. M, IKEGAKI, N

“…Mouse eck, a member of the EPH gene family, has been mapped to mouse chromosome 4. The syntenic relationship between this chromosome and human chromosome 1…”
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Trophic effects of basic fibroblast growth factor (bFGF) on differentiated oligodendroglia: a mechanism for regeneration of the oligodendroglial lineage by Grinspan, J B, Stern, J L, Franceschini, B, Pleasure, D

“…We have investigated the effect of basic fibroblast growth factor (bFGF) on the proliferation and phenotype of differentiated oligodendroglia. Using primary…”
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Conditional ablation of astroglial CCL2 suppresses CNS accumulation of M1 macrophages and preserves axons in mice with MOG peptide EAE by Moreno, Monica, Bannerman, Peter, Ma, Joyce, Guo, Fuzheng, Miers, Laird, Soulika, Athena M, Pleasure, David

“…Current multiple sclerosis (MS) therapies only partially prevent chronically worsening neurological deficits, which are largely attributable to progressive…”
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Basic fibroblast growth factor prevents cAMP-induced apoptosis in cultured Schwann cells by Shaw, R., Cianchetti, R., Pleasure, D., Kreider, B.

“…Peripheral nerve axotomy induces apoptosis in Schwann cell precursors; basic fibroblast growth factor (bFGF) protects these cells from axotomy‐induced…”
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Cloning of a novel putative protein kinase having a leucine zipper domain from human brain by Reddy, U R, Pleasure, D

“…We report a novel putative serine/threonine protein kinase containing a leucine-zipper domain, isolated from an human neuronal cell line. The teratocarcinoma…”
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Platelet-derived growth factor and regulation of Schwann cell proliferation in vivo by Hardy, M, Reddy, U R, Pleasure, D

“…To examine the role of platelet-derived growth factor (PDGF) in the in vivo regulation of Schwann cell proliferation, steady-state levels of mRNAs encoding…”
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Cerebral white matter contains PDGF-responsive precursors to O2A cells by Grinspan, JB, Stern, JL, Pustilnik, SM, Pleasure, D

“…Cells dissociated from the cerebral white matter of immature rats were maintained in monolayer culture. Treatment with platelet-derived growth factor (PDGF)…”
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