Search Results - "PLATTON, S."

The incidence and magnitude of fibrinolytic activation in trauma patients by RAZA, I., DAVENPORT, R., ROURKE, C., PLATTON, S., MANSON, J., SPOORS, C., KHAN, S., De'ATH, H. D., ALLARD, S., HART, D. P., PASI, K. J., HUNT, B. J., STANWORTH, S., MacCALLUM, P. K., BROHI, K.

“…Background:  Trauma is a global disease, with over 2.5 million deaths annually from hemorrhage and coagulopathy. Overt hyperfibrinolysis is rare in trauma, and…”
Get full text

Every minute counts: A comparison of thawing times and haemostatic quality of plasma thawed at 37°C and 45°C using four different methods by McCullagh, J., Booth, C., Lancut, J., Platton, S., Richards, P., Green, L.

“…Background Having faster plasma thawing devices could be beneficial for transfusion services, as it may improve the rapid availability of thawed plasma for…”
Get full text

Prothrombin complex concentrate vs. fresh frozen plasma in adult patients undergoing heart surgery – a pilot randomised controlled trial (PROPHESY trial) by Green, L., Roberts, N., Cooper, J., Agarwal, S., Brunskill, S.J., Chang, I., Gill, R., Johnston, A., Klein, A. A., Platton, S., Rossi, A., Sepehripour, A., Stanworth, S., Monk, V., O'Brien, B.

“…Summary There is equipoise regarding the use of prothrombin complex concentrate vs. fresh frozen plasma in bleeding patients undergoing cardiac surgery. We…”
Get full text

Optimization of pre‐analytical heat treatment for inhibitor detection in haemophilia A by Batty, P., Hart, D. P., Platton, S.

“…Introduction Factor VIII (FVIII) antibody formation is the greatest clinical and laboratory challenge within the haemophilia centre. The Nijmegen‐Bethesda…”
Get full text

Impact of prothrombin complex concentrate and fresh frozen plasma on correction of haemostatic abnormalities in bleeding patients undergoing cardiac surgery (PROPHESY trial results) by Green, L., Roberts, N., Platton, S., O’Brien, B., Agarwal, S., Gill, R., Klein, A. A., Stanworth, S., Cooper, J.

“…There is increased interest in the use of prothrombin complex concentrate (PCC) to treat bleeding in patients who do not require reversal of vitamin K…”
Get full text

A computer‐based model to assess costs associated with the use of factor VIII and factor IX one‐stage and chromogenic activity assays by Kitchen, S., Blakemore, J., Friedman, K. D., Hart, D. P., Ko, R. H., Perry, D., Platton, S., Tan‐Castillo, D., Young, G., Luddington, R. J.

“…Essentials Chromogenic factor VIII and factor IX assays have not been widely adopted partly due to perceived cost. Chromogenic assays may be needed for…”
Get full text

Safety and efficacy of a von Willebrand factor/factor VIII concentrate (Wilate®): a single centre experience by Batty, P., Chen, Y. -H., Bowles, L., Hart, D. P., Platton, S., Pasi, K. J.

“…Summary von Willebrand disease (VWD) is the commonest inherited bleeding disorder. Management of major surgery or bleeding often requires treatment with a…”
Get full text

Wilate use in 47 children with von Willebrand disease: the North London paediatric haemophilia network experience by Khair, K., Batty, P., Riat, R., Bowles, L., Burgess, C., Chen, Y. -H., Hart, D., Platton, S., Pasi, J., Liesner, R.

“…Summary Children with von Willebrand disease (VWD) in whom DDAVP is ineffective or contraindicated require treatment with a coagulation factor concentrate…”
Get full text

PB1126 The Use of Slope Ratio to Identify the Presence of Inhibitors in One- Stage Intrinsic Clotting Factor Assays on Sysmex CN-Series Analysers by Platton, S., Narisada, R., Ram, K.

Get full text

Phase I clinical trial of oral curcumin: Biomarkers of systemic activity and compliance by SHARMA, Ricky A, EUDEN, Stephanie A, PIRMOHAMED, Munir, GESCHER, Andreas J, STEWARD, William P, PLATTON, Sharon L, COOKE, Darren N, SHAFAYAT, Aisha, HEWITT, Heather R, MARCZYLO, Timothy H, MORGAN, Bruno, HEMINGWAY, David, PLUMMER, Simon M

“…Curcumin, a polyphenolic antioxidant derived from a dietary spice, exhibits anticancer activity in rodents and in humans. Its efficacy appears to be related to…”
Get full text

ENHANCED CELL GROWTH OF PRIMARY CULTURES OF PANCREATIC CELLS FROM HYPERINSULINAEMIC PATIENTS USING LOW GRAVITY CULTURE by Platton, S, Webb, M A, Skouteris, G, James, R F L

Get full text