Search Results - "PIZZATO, Massimo"

SERINC5 protein inhibits HIV-1 fusion pore formation by promoting functional inactivation of envelope glycoproteins by Sood, Chetan, Marin, Mariana, Chande, Ajit, Pizzato, Massimo, Melikyan, Gregory B.

“…The host proteins, SERINC3 and SERINC5, have been recently shown to incorporate into HIV-1 particles and compromise their ability to fuse with target cells, an…”
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HIV-1 Nef promotes infection by excluding SERINC5 from virion incorporation by Rosa, Annachiara, Chande, Ajit, Ziglio, Serena, De Sanctis, Veronica, Bertorelli, Roberto, Goh, Shih Lin, McCauley, Sean M., Nowosielska, Anetta, Antonarakis, Stylianos E., Luban, Jeremy, Santoni, Federico Andrea, Pizzato, Massimo

“…HIV-1 Nef, a protein important for the development of AIDS, has well-characterized effects on host membrane trafficking and receptor downregulation. By an…”
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S2 from equine infectious anemia virus is an infectivity factor which counteracts the retroviral inhibitors SERINC5 and SERINC3 by Chande, Ajit, Cuccurullo, Emilia Cristiana, Rosa, Annachiara, Ziglio, Serena, Carpenter, Susan, Pizzato, Massimo

“…The lentivirus equine infectious anemia virus (EIAV) encodes the small protein S2, a pathogenic determinant that is important for virus replication and disease…”
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MLV glycosylated-Gag is an infectivity factor that rescues Nef-deficient HIV-1 by Pizzato, Massimo

“…Optimal infectivity of HIV-1 virions requires synthesis of the HIV-1 regulatory protein Nef in some producer cells but not others. A survey of 18 lymphoid cell…”
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Identification of Gammaretroviruses Constitutively Released from Cell Lines Used for Human Immunodeficiency Virus Research by TAKEUCHI, Yasuhiro, MCCLURE, Myra O, PIZZATO, Massimo

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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A bipartite structural organization defines the SERINC family of HIV-1 restriction factors by Pye, Valerie E., Rosa, Annachiara, Bertelli, Cinzia, Struwe, Weston B., Maslen, Sarah L., Corey, Robin, Liko, Idlir, Hassall, Mark, Mattiuzzo, Giada, Ballandras-Colas, Allison, Nans, Andrea, Takeuchi, Yasuhiro, Stansfeld, Phillip J., Skehel, J. Mark, Robinson, Carol V., Pizzato, Massimo, Cherepanov, Peter

“…The human integral membrane protein SERINC5 potently restricts HIV-1 infectivity and sensitizes the virus to antibody-mediated neutralization. Here, using…”
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Quantification of reverse transcriptase activity by real-time PCR as a fast and accurate method for titration of HIV, lenti- and retroviral vectors by Vermeire, Jolien, Naessens, Evelien, Vanderstraeten, Hanne, Landi, Alessia, Iannucci, Veronica, Van Nuffel, Anouk, Taghon, Tom, Pizzato, Massimo, Verhasselt, Bruno

“…Quantification of retroviruses in cell culture supernatants and other biological preparations is required in a diverse spectrum of laboratories and…”
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Host Restriction Factors Modulating HIV Latency and Replication in Macrophages by Pagani, Isabel, Demela, Pietro, Ghezzi, Silvia, Vicenzi, Elisa, Pizzato, Massimo, Poli, Guido

“…In addition to CD4 T lymphocytes, myeloid cells and, particularly, differentiated macrophages are targets of human immunodeficiency virus type-1 (HIV-1)…”
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The host-cell restriction factor SERINC5 restricts HIV-1 infectivity without altering the lipid composition and organization of viral particles by Trautz, Birthe, Wiedemann, Hannah, Lüchtenborg, Christian, Pierini, Virginia, Kranich, Jan, Glass, Bärbel, Kräusslich, Hans-Georg, Brocker, Thomas, Pizzato, Massimo, Ruggieri, Alessia, Brügger, Britta, Fackler, Oliver T.

“…The host-cell restriction factor SERINC5 potently suppresses the infectivity of HIV, type 1 (HIV-1) particles, and is counteracted by the viral pathogenesis…”
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The Antagonism of HIV-1 Nef to SERINC5 Particle Infectivity Restriction Involves the Counteraction of Virion-Associated Pools of the Restriction Factor by Trautz, Birthe, Pierini, Virginia, Wombacher, Rebecka, Stolp, Bettina, Chase, Amanda J, Pizzato, Massimo, Fackler, Oliver T

“…SERINC3 (serine incorporator 3) and SERINC5 are recently identified host cell inhibitors of HIV-1 particle infectivity that are counteracted by the viral…”
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Impaired ability of Nef to counteract SERINC5 is associated with reduced plasma viremia in HIV-infected individuals by Toyoda, Mako, Kamori, Doreen, Tan, Toong Seng, Goebuchi, Kageaki, Ohashi, Jun, Carlson, Jonathan, Kawana-Tachikawa, Ai, Gatanaga, Hiroyuki, Oka, Shinichi, Pizzato, Massimo, Ueno, Takamasa

“…HIV-1 Nef plays an essential role in enhancing virion infectivity by antagonizing the host restriction molecule SERINC5. Because Nef is highly polymorphic due…”
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SERINC5 as a New Restriction Factor for Human Immunodeficiency Virus and Murine Leukemia Virus by Firrito, Claudia, Bertelli, Cinzia, Vanzo, Teresa, Chande, Ajit, Pizzato, Massimo

“…SERINC genes encode for homologous multipass transmembrane proteins with unknown cellular function, despite being highly conserved across eukaryotes. Among the…”
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SARS-CoV-2 and the Host Cell: A Tale of Interactions by Pizzato, Massimo, Baraldi, Chiara, Boscato Sopetto, Giulia, Finozzi, Davide, Gentile, Carmelo, Gentile, Michele Domenico, Marconi, Roberta, Paladino, Dalila, Raoss, Alberto, Riedmiller, Ilary, Ur Rehman, Hamza, Santini, Annalisa, Succetti, Valerio, Volpini, Lorenzo

“…The ability of a virus to spread between individuals, its replication capacity and the clinical course of the infection are macroscopic consequences of a…”
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SARS-CoV-2 vaccination elicits unconventional IgM specific responses in naïve and previously COVID-19-infected individuals by Ruggiero, Alessandra, Piubelli, Chiara, Calciano, Lucia, Accordini, Simone, Valenti, Maria Teresa, Carbonare, Luca Dalle, Siracusano, Gabriel, Temperton, Nigel, Tiberti, Natalia, Longoni, Silvia Stefania, Pizzato, Massimo, Accordini, Silvia, Fantoni, Tobia, Lopalco, Lucia, Beretta, Alberto, Bisoffi, Zeno, Zipeto, Donato

“…Currently, evaluation of the IgG antibodies specific for the SARS-CoV-2 Spike protein following vaccination is used worldwide to estimate vaccine response…”
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SARS-CoV-2 can recruit a heme metabolite to evade antibody immunity by Rosa, Annachiara, Pye, Valerie E, Graham, Carl, Muir, Luke, Seow, Jeffrey, Ng, Kevin W, Cook, Nicola J, Rees-Spear, Chloe, Parker, Eleanor, Dos Santos, Mariana Silva, Rosadas, Carolina, Susana, Alberto, Rhys, Hefin, Nans, Andrea, Masino, Laura, Roustan, Chloe, Christodoulou, Evangelos, Ulferts, Rachel, Wrobel, Antoni G, Short, Charlotte-Eve, Fertleman, Michael, Sanders, Rogier W, Heaney, Judith, Spyer, Moira, Kjær, Svend, Riddell, Andy, Malim, Michael H, Beale, Rupert, MacRae, James I, Taylor, Graham P, Nastouli, Eleni, van Gils, Marit J, Rosenthal, Peter B, Pizzato, Massimo, McClure, Myra O, Tedder, Richard S, Kassiotis, George, McCoy, Laura E, Doores, Katie J, Cherepanov, Peter

“…The coronaviral spike is the dominant viral antigen and the target of neutralizing antibodies. We show that SARS-CoV-2 spike binds biliverdin and bilirubin,…”
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Influence of Different Glycoproteins and of the Virion Core on SERINC5 Antiviral Activity by Diehl, William E, Guney, Mehmet H, Vanzo, Teresa, Kyawe, Pyae P, White, Judith M, Pizzato, Massimo, Luban, Jeremy

“…Host plasma membrane protein SERINC5 is incorporated into budding retrovirus particles where it blocks subsequent entry into susceptible target cells. Three…”
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Trends and symptoms of SARS-CoV-2 infection: a longitudinal study on an Alpine population representative sample by Barbieri, Giulia, Pizzato, Massimo, Gögele, Martin, Giardiello, Daniele, Weichenberger, Christian X, Foco, Luisa, Bottigliengo, Daniele, Bertelli, Cinzia, Barin, Laura, Lundin, Rebecca, Pramstaller, Peter P, Pattaro, Cristian, Melotti, Roberto

“…ObjectivesThe continuous monitoring of SARS-CoV-2 infection waves and the emergence of novel pathogens pose a challenge for effective public health…”
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The antiviral activity of rodent and lagomorph SERINC3 and SERINC5 is counteracted by known viral antagonists by de Sousa-Pereira, Patrícia, Abrantes, Joana, Bauernfried, Stefan, Pierini, Virginia, Esteves, Pedro José, Keppler, Oliver T, Pizzato, Massimo, Hornung, Veit, Fackler, Oliver T, Baldauf, Hanna-Mari

“…A first step towards the development of a human immunodeficiency virus (HIV) animal model has been the identification and surmounting of species-specific…”
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A Conserved Acidic Residue in the C-Terminal Flexible Loop of HIV-1 Nef Contributes to the Activity of SERINC5 and CD4 Downregulation by Firrito, Claudia, Bertelli, Cinzia, Rosa, Annachiara, Chande, Ajit, Ananth, Swetha, van Dijk, Hannah, Fackler, Oliver T, Stoneham, Charlotte, Singh, Rajendra, Guatelli, John, Pizzato, Massimo

“…The host transmembrane protein SERINC5 is incorporated into retrovirus particles and inhibits HIV-1 infectivity. The lentiviral Nef protein counteracts SERINC5…”
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Viral particles imaging through evanescent wave scattering in a total internal reflection laser microscope by Lo Savio, Roberto, Piselli, Sara, Bertelli, Cinzia, Pizzato, Massimo, Carloni, Adolfo

“…Optical imaging of objects at the nanometric scale is limited by light diffraction, and for this reason several sub-diffractive optical microscopy techniques…”
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