Search Results - "PIULATS, Jaume"

Amide-to-Ester Substitution Allows Fine-Tuning of the Cyclopeptide Conformational Ensemble by Cupido, Tommaso, Spengler, Jan, Ruiz-Rodriguez, Javier, Adan, Jaume, Mitjans, Francesc, Piulats, Jaume, Albericio, Fernando

“…Without affecting the overall 3D structure, amide‐to‐ester backbone substitution (or ester scan) exerts a pronounced influence on the conformational…”
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Kidney Androgen-regulated Protein Interacts with Cyclophilin B and Reduces Cyclosporine A-mediated Toxicity in Proximal Tubule Cells by Cebrián, Cristina, Aresté, Cristina, Nicolás, Antoni, Olivé, Pere, Carceller, Ana, Piulats, Jaume, Meseguer, Anna

“…The gene for kidney androgen-regulated protein (KAP) is the most abundant and specific gene expressed in mouse kidney proximal tubule cells, where it is…”
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Amide-to-Ester Substitution Allows Fine-Tuning of the Cyclopeptide Conformational Ensemble by Cupido, Tommaso, Spengler, Jan, Ruiz-Rodriguez, Javier, Adan, Jaume, Mitjans, Francesc, Piulats, Jaume, Albericio, Fernando

“…Ohne die dreidimensionale Gesamtstruktur zu beeinflussen, hat eine Substitution von Amid‐ gegen Esterfunktionen im Molekülgerüst deutliche Auswirkungen auf das…”
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Synthesis and biological evaluation of novel indolocarbazoles with anti-angiogenic activity by Acero, Nuria, Braña, Miguel F., Añorbe, Loreto, Domínguez, Gema, Muñoz-Mingarro, Dolores, Mitjans, Francesc, Piulats, Jaume

“…A novel series of indolocarbazoles were synthesized and their antiproliferative activity against HUVEC, LoVo, DLD-1 and ST-486 cell lines, was investigated…”
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In vivo therapy of malignant melanoma by means of antagonists of αv integrins by Mitjans, Francesc, Meyer, Tim, Fittschen, Claus, Goodman, Simon, Jonczyk, Alfred, Marshall, John F., Reyes, German, Piulats, Jaume

“…Integrin αvβ3 (vitronectin receptor) has been implicated in human malignant melanoma progression and angiogenesis as a receptor that provides survival signals…”
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Inhibition of human immunodeficiency virus type 1 infection in macrophages by an alpha-v integrin blocking antibody by Bosch, Berta, Clotet-Codina, Imma, Blanco, Julià, Pauls, Eduardo, Coma, Gemma, Cedeño, Samandhy, Mitjans, Francesc, Llano, Anuska, Bofill, Margarita, Clotet, Bonaventura, Piulats, Jaume, Esté, José A.

“…Macrophages are key cells for HIV infection and HIV spreading inside the organism. Macrophages cultured in vitro can be successfully infected after…”
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Anti-migratory and anti-angiogenic effect of p16 : A novel localization at membrane ruffles and lamellipodia in endothelial cells by ALHAJA, Elena, ADAN, Jaume, PIULATS, Jaume, PAGAN, Roser, MITJANS, Francesc, CASCALLO, Manel, RODRIGUEZ, Mercè, NOE, Veronique, CIUDAD, Carlos J, MAZO, Adela, VILARO, Senen

“…Recent evidence has established different functions for the tumor suppressor protein, p16(INK4A) aside from controlling the cell cycle. Here we report that…”
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Impaired responsiveness to angiotensin II in experimental cirrhosis: role of nitric oxide by Castro, A, Jiménez, W, Clària, J, Ros, J, Martínez, J M, Bosch, M, Arroyo, V, Piulats, J, Rivera, F, Rodés, J

“…Impaired vascular responsiveness to angiotensin II is a common feature in human cirrhosis with ascites. The aim of this study was to investigate whether…”
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Orthotopic xenografts of human pancreatic carcinomas acquire genetic aberrations during dissemination in nude mice by REYES, G, VILLANUEVA, A, GARCIA, C, SANCHO, F. J, PIULATS, J, LLUIS, F, CAPELLA, G

“…Orthotopic transplantation of human tumors in nude mice reproduces the pattern of local growth and distal dissemination. The aim of our study was to determine…”
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Synthesis of OligonucleotidePeptide Conjugates Carrying the c-myc Peptide Epitope as Recognition System by Frieden, Miriam, Aviñó, Anna, Tarrasón, Gema, Escorihuela, Marta, Piulats, Jaume, Eritja, Ramon

“…Oligonucleotidepeptide conjugates 1–3 were prepared by sequential addition of the appropriate Boc‐protected amino acids, followed by nucleoside…”
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Synthesis of Oligodeoxynucleotides Containing N 4-Mercaptoethylcytosine and Their Use in the Preparation of Oligonucleotide−Peptide Conjugates Carrying c-myc Tag-Sequence by Gottschling, Dirk, Seliger, Hartmut, Tarrasón, Gema, Piulats, Jaume, Eritja, Ramon

“…The preparation and properties of oligodeoxynucleotides containing mercaptoethyl groups at position N-4 of cytosine are described. The resulting…”
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Serum amino acid levels after permanent middle cerebral artery occlusion in the rat by Puig, N, Dávalos, A, Adan, J, Piulats, J, Martínez, J M, Castillo, J

“…High levels of glutamate in plasma and cerebrospinal fluid (CSF) have been demonstrated in patients with acute ischemic stroke. Whereas this glutamate increase…”
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RGD Peptides and Monoclonal Antibodies, Antagonists of [alpha]v-Integrin, Enter the Cells by Independent Endocytic Pathways by Castel, Susanna, Pagan, Roser, Mitjans, Francesc, Piulats, Jaume, Goodman, Simon, Jonczyk, Alfred, Huber, Florian, Vilaró, Senén, Reina, Manuel

“…Cyclic synthetic peptides containing the arginine-glycine-aspartate motif (cRGD) and monoclonal antibodies (mAbs) targeted for individual integrins have been…”
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RGD Peptides and Monoclonal Antibodies, Antagonists of αv-Integrin, Enter the Cells by Independent Endocytic Pathways by Castel, Susanna, Pagan, Roser, Mitjans, Francesc, Piulats, Jaume, Goodman, Simon, Jonczyk, Alfred, Huber, Florian, Vilaró, Senén, Reina, Manuel

“…Cyclic synthetic peptides containing the arginine-glycine-aspartate motif (cRGD) and monoclonal antibodies (mAbs) targeted for individual integrins have been…”
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Synthesis and biological evaluation of novel bisindolylmaleimides that inhibit vascular endothelial cell proliferation by Braña, Miguel F, Añorbe, Loreto, Tarrasón, Gema, Mitjans, Francesc, Piulats, Jaume

“…A novel class of bisindolylmaleimides were synthesized and antiproliferative activities (HUVECs and three tumor cell lines) of these compounds were…”
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TGF-B determines leukocyte-endothelial cell interactions in experimental colon cancer by Bessa, Xavier, Castells, Antoni, Mitjans, Francese, Elizalde, J. Ignasi, Panes, Julian, Pinol, Virginia, Piulats, Jaume, Pique, Josep M.

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Alpha v integrin antagonists induce the disassembly of focal contacts in melanoma cells by Castel, Susanna, Pagan, Roser, García, Raquel, Casaroli-Marano, Ricardo P., Reina, Manuel, Mitjans, Francesc, Piulats, Jaume, Vilaró, Senén

“…In recent years, several antagonists of αvβ3 have been used to develop therapeutic approaches to the treatment of melanoma neoplasia. We studied the effects of…”
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Intracellular distribution of digoxigenin-labeled phosphorothioate oligonucleotides by Tarrasón, G, Bellido, D, Eritja, R, Vilaró, S, Piulats, J

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Effects of NMDA-R1 antisense oligodeoxynucleotide administration: behavioral and radioligand binding studies by Zapata, Agustin, Capdevila, Jordi L, Tarrason, Gemma, Adan, Jaume, Martı́nez, Josep Maria, Piulats, Jaume, Trullas, Ramon

“…The effects of an antisense phosphodiester oligodeoxynucleotide (ODN) directed to the NR1 subunit of the NMDA receptor mRNA and of its corresponding sense ODN…”
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Amide‐to‐Ester Substitution Allows Fine‐Tuning of the Cyclopeptide Conformational Ensemble by Cupido, Tommaso, Spengler, Jan, Ruiz‐Rodriguez, Javier, Adan, Jaume, Mitjans, Francesc, Piulats, Jaume, Albericio, Fernando

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