Search Results - "PISCOPO, Paola"
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Circulating miRNAs as biomarkers for neurodegenerative disorders
Published in Molecules (Basel, Switzerland) (23-05-2014)“…Neurodegenerative disorders, such as Alzheimer's disease (AD), Parkinson's disease (PD) and frontotemporal dementias (FTD), are considered distinct entities,…”
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A Sex Perspective in Neurodegenerative Diseases: microRNAs as Possible Peripheral Biomarkers
Published in International journal of molecular sciences (23-04-2021)“…Sex is a significant variable in the prevalence and incidence of neurological disorders. Sex differences exist in neurodegenerative disorders (NDs), where sex…”
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Safety and Efficacy of Monoclonal Antibodies for Alzheimer's Disease: A Systematic Review and Meta-Analysis of Published and Unpublished Clinical Trials
Published in Journal of Alzheimer's disease (01-01-2022)“…Monoclonal antibodies (mAbs) are currently among the most investigated targets for potential disease-modifying therapies in Alzheimer's disease (AD). Our…”
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A Plasma Circular RNA Profile Differentiates Subjects with Alzheimer's Disease and Mild Cognitive Impairment from Healthy Controls
Published in International journal of molecular sciences (31-10-2022)“…The most frequently used biomarkers to support the diagnosis of Alzheimer’s Disease (AD) are Aβ42, total-Tau, and phospho-tau protein levels in CSF. Moreover,…”
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Anticancer drugs repurposed for Alzheimer's disease: a systematic review
Published in Alzheimer's research & therapy (05-05-2021)“…The relationship between cancer and dementia is triggering growing research interest. Several preclinical studies have provided the biological rationale for…”
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Autosomal Dominant Frontotemporal Lobar Degeneration Due to the C9ORF72 Hexanucleotide Repeat Expansion: Late-Onset Psychotic Clinical Presentation
Published in Biological psychiatry (1969) (01-09-2013)“…Background A hexanucleotide repeat expansion in the first intron of C9ORF72 has been shown to be responsible for a high number of familial cases of amyotrophic…”
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M2 Receptor Activation Counteracts the Glioblastoma Cancer Stem Cell Response to Hypoxia Condition
Published in International journal of molecular sciences (02-03-2020)“…Glioblastoma multiforme (GBM) is the most malignant brain tumor. Hypoxic condition is a predominant feature of the GBM contributing to tumor growth and…”
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Identification of miRNAs regulating MAPT expression and their analysis in plasma of patients with dementia
Published in Frontiers in molecular neuroscience (31-05-2023)“…Dementia is one of the most common diseases in elderly people and hundreds of thousand new cases per year of Alzheimer's disease (AD) are estimated. While the…”
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A multicomponent personalized prevention program in the primary care setting: a randomized clinical trial in older people with noncommunicable chronic diseases (Primacare_P3 study)
Published in Current controlled trials in cardiovascular medicine (13-09-2024)“…Multicomponent interventions based on a comprehensive geriatric assessment (CGA) could promote active aging and improve health status in older people with…”
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Adverse Events in Italian Nursing Homes During the COVID-19 Epidemic: A National Survey
Published in Frontiers in psychiatry (30-09-2020)“…Older people living in nursing homes (NHs) are particularly vulnerable in the ongoing COVID-19 pandemic, due to the high prevalence of chronic diseases and…”
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In Vitro Evaluation of the Antioxidant Capacity of 3,3-Disubstituted-3H-benzofuran-2-one Derivatives in a Cellular Model of Neurodegeneration
Published in Life (Basel, Switzerland) (22-03-2024)“…Oxidative stress represents a hallmark for many degenerative pathologies of the Central Nervous System. Throughout life, the constant pressure of noxious…”
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The Encapsulation of Citicoline within Solid Lipid Nanoparticles Enhances Its Capability to Counteract the 6-Hydroxydopamine-Induced Cytotoxicity in Human Neuroblastoma SH-SY5Y Cells
Published in Pharmaceutics (30-08-2022)“…(1) Backgrond: Considering the positive effects of citicoline (CIT) in the management of some neurodegenerative diseases, the aim of this work was to develop…”
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A Systematic Review on Drugs Acting as Nicotinic Acetylcholine Receptor Agonists in the Treatment of Dementia
Published in Cells (Basel, Switzerland) (01-01-2024)“…Acetylcholine signaling is attenuated in early Alzheimer's disease (AD) and other dementias. A significant reduction in the expression of nicotinic…”
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Can Repetitive Transcranial Magnetic Stimulation (rTMS) Promote Neurogenesis and Axonogenesis in Subacute Human Ischemic Stroke?
Published in Biomedicines (01-03-2024)“…Ischemic stroke may trigger neuroplastic changes via proliferation, migration towards the lesion, and differentiation of neuroprogenitor cells into mature…”
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Prevalence of amyotrophic lateral sclerosis in Latium region, Italy
Published in Brain and behavior (01-12-2021)“…Objective Prevalence estimate of amyotrophic lateral sclerosis (ALS) ranged between 1.1/100,000 and 11.2/100,000 inhabitants with different design of the study…”
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SARS-CoV-2 infection predicts larger infarct volume in patients with acute ischemic stroke
Published in Frontiers in cardiovascular medicine (10-01-2023)“…Acute ischemic stroke (AIS) is a fearful complication of Coronavirus Disease-2019 (COVID-19). Aims of this study were to compare clinical/radiological…”
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Development of a prediction model of conversion to Alzheimer's disease in people with mild cognitive impairment: the statistical analysis plan of the INTERCEPTOR project
Published in Diagnostic and prognostic research (25-07-2024)“…In recent years, significant efforts have been directed towards the research and development of disease-modifying therapies for dementia. These drugs focus on…”
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The National Italian Guidelines on the diagnosis and treatment of children with pediatric ataxias
Published in Frontiers in neurology (04-10-2022)“…Background Ataxia is a rare neurological condition causing a deficit in the coordination of motor activities, preventing the fluidity of movements. Children…”
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Biofeedback stimulation in patients with age-related macular degeneration: comparison between 2 different methods
Published in Canadian journal of ophthalmology (01-10-2013)“…Abstract Objective To evaluate changes in patient’s visual performance after rehabilitation training with 2 different biofeedback training programs offered by…”
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