Search Results - "PIPER, R. D"

TNF and TNFR polymorphisms in severe sepsis and septic shock: a prospective multicentre study by Gordon, A C, Lagan, A L, Aganna, E, Cheung, L, Peters, C J, McDermott, M F, Millo, J L, Welsh, K I, Holloway, P, Hitman, G A, Piper, R D, Garrard, C S, Hinds, C J

“…Tumour necrosis factor (TNF) is an important pro-inflammatory cytokine produced in sepsis. Studies examining the association of individual TNF single…”
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Lineage-Restricted Neural Precursors Can Be Isolated from Both the Mouse Neural Tube and Cultured ES Cells by Mujtaba, T., Piper, D.R., Kalyani, A., Groves, A.K., Lucero, M.T., Rao, M.S.

“…We have previously identified multipotent neuroepithelial (NEP) stem cells and lineage-restricted, self-renewing precursor cells termed NRPs (neuron-restricted…”
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Microcirculatory changes in rat skeletal muscle in sepsis by Piper, R D, Pitt-Hyde, M, Li, F, Sibbald, W J, Potter, R F

“…The aim of this study was to confirm that microvascular perfusion was abnormal during the early phases of normotensive sepsis and to determine whether these…”
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Effects of isoproterenol on myocardial structure and function in septic rats by Piper, R. D, Li, F. Y, Myers, M. L, Sibbald, W. J

“…1  A. C. Burton Vascular Biology Laboratory and 2  Cardiovascular Surgery, London Health Sciences Center, Victoria Campus, London, Ontario, Canada N6A 4G5 In…”
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Introducing Critical Appraisal to studies of animal models investigating novel therapies in sepsis by Piper, Richard D, Cook, Deborah J, Bone, Roger C, Sibbald, William J

“…OBJECTIVESTo discuss theoretical and practical aspects relating to the design of animal studies investigating the efficacy of novel therapeutic agents for the…”
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Cortical blood flow changes during spreading depression in cats by Piper, R D, Lambert, G A, Duckworth, J W

“…Changes in cortical blood flow and cerebrovascular activity occurring during and after cortical spreading depression (CSD) were studied in…”
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Inhalational anesthetics inhibit spreading depression: relevance to migraine by Piper, R D, Lambert, G A

“…Cortical spreading depression (SD) has not been shown in the human neocortex by direct cortical recordings. However, animal studies suggest that cortical…”
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Microvascular perfusion deficits are not a prerequisite for mucosal injury in septic rats by Nevière, R R, Pitt-Hyde, M L, Piper, R D, Sibbald, W J, Potter, R F

“…Our major objective was to investigate whether injury to the mucosa of the small intestine occurred in a normotensive model of sepsis and whether such injury…”
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Leukocyte activation and flow behavior in rat skeletal muscle in sepsis by PIPER, R. D, PITT-HYDE, M. L, ANDERSON, L. A, SIBBALD, W. J, POTTER, R. F

“…In animal models of endotoxemia, sepsis is associated with the accumulation of leukocytes and altered microvascular perfusion. In order to test the hypothesis…”
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Structure-function relationships in the septic rat heart by PIPER, R. D, FU YAN LI, MYERS, M. L, SIBBALD, W. J

“…Myocardial edema and histologic changes consistent with tissue injury are reported in association with sepsis-induced myocardial depression. The objective of…”
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Cortical spreading depression does not result in the release of calcitonin gene-related peptide into the external jugular vein of the cat: relevance to human migraine by Piper, R D, Edvinsson, L, Ekman, R, Lambert, G A

“…There is circumstantial evidence that cortical spreading depression (SD) may account for the scotoma and the "spreading cortical oligemia" seen during migraine…”
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Immunocytochemical and Physiological Characterization of a Population of Cultured Human Neural Precursors by Piper, David R, Mujtaba, Tahmina, Rao, Mahendra S, Lucero, Mary T

“…  1 Department of Physiology, University of Utah School of Medicine, Salt Lake City 84108; and   2 Department of Neurobiology and Anatomy, University of Utah…”
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Identification and characterization of neuronal precursors and their progeny from human fetal tissue by Piper, David R., Mujtaba, Tahmina, Keyoung, Hansoo, Roy, Neeta S., Goldman, Steven A., Rao, Mahendra S., Lucero, Mary T.

“…We have examined primary human neuronal precursors (HNPs) from 18–22‐week‐old fetuses. We showed that E‐NCAM/MAP2/β‐III tubulin‐immunoreactive neuronal…”
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Pressor response to electrical and chemical stimulation of nucleus raphe dorsalis in the cat by PIPER, R. D, GOADSBY, P. J

“…The dorsal raphe nucleus was stimulated electrically and chemically in 57 cats with blood pressure being measured by an arterial catheter. Blood pressure rose…”
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Effect of stimulation of nucleus raphe dorsalis on carotid blood flow. I. The monkey by Goadsby, P J, Piper, R D, Lambert, G A, Lance, J W

“…The dorsal raphe nucleus (DRN) and surrounding midbrain of 16 anaesthetized monkeys were stimulated electrically, and carotid blood flows were measured with…”
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MYOCARDIAL DYSFUNCTION IN SEPSIS by Piper, Richard D

“…SUMMARY 1. Sepsis is the leading reversible cause of death in patients requiring modern intensive care services. 2. In this group of patients, death usually…”
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Effect of stimulation of nucleus raphe dorsalis on carotid blood flow. II. The cat by Goadsby, P J, Piper, R D, Lambert, G A, Lance, J W

“…The dorsal raphe nucleus (DRN) and surrounding midbrain of 74 cats were stimulated both electrically and chemically, and carotid flows were measured with…”
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Calcium signalling in squid olfactory receptor neurons by Piper, D R, Lucero, M T

“…Isolated squid olfactory receptor neurons respond to dopamine and betaine with hyperpolarizing conductances. We used Ca(2+) imaging techniques to determine if…”
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Voltage- and Ca(2+)-gated currents in zebrafish olfactory receptor neurons by Corotto, F S, Piper, D R, Chen, N, Michel, W C

“…Voltage- and Ca(2+)-gated currents were recorded from isolated olfactory receptor neurons (ORNs) of the zebrafish Danio rerio using the whole-cell…”
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Electrolytic Production of Uranium Metal from Uranium Oxides by Piper, R. D, Leifield, R. F

“…Massive uranium metal which exceeds AEC specifications for purity was produced with nearly 100% recovery from uranium oxides. Electrolysis at 1150 deg C in a…”
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