Search Results - "PINTO, Maria Do Carmo F. R"

Synthesis and anti- Trypanosoma cruzi activity of derivatives from nor-lapachones and lapachones by da Silva Júnior, Eufrânio N., de Souza, Maria Cecília B.V., Fernandes, Michelle C., Menna-Barreto, Rubem F.S., Pinto, Maria do Carmo F.R., de Assis Lopes, Francisco, de Simone, Carlos Alberto, Andrade, Carlos Kleber Z., Pinto, Antônio V., Ferreira, Vitor F., de Castro, Solange L.

“…New naphthoquinone derivatives were synthesized and assayed against bloodstream trypomastigote forms of Trypanosoma cruzi, the etiological agent of Chagas’…”
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New oxirane derivatives of 1,4-naphthoquinones and their evaluation against T. cruzi epimastigote forms by Carneiro, Paula F., do Nascimento, Samara B., Pinto, Antonio V., Pinto, Maria do Carmo F.R., Lechuga, Guilherme C., Santos, Dilvani O., dos Santos Júnior, Helvécio M., Resende, Jackson A.L.C., Bourguignon, Saulo C., Ferreira, Vitor F.

“…New oxirane derivatives were synthesized using six naphthoquinones as the starting material. Our biological results showed that these oxiranes acted as…”
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Identification of Nor-β-Lapachone Derivatives as Potential Antibacterial Compounds against Enterococcus faecalis Clinical Strain by Lourenço, André L, Abreu, Paula A, Leal, Bruno, da Silva Júnior, Eufrânio N, Pinto, Antonio V, Pinto, Maria do Carmo F. R, Souza, Alessandra M. T, Novais, Juliana S, Paiva, Marcela B, Cabral, Lucio M, Rodrigues, Carlos R, Ferreira, Vitor F, Castro, Helena C

“…A broad-spectrum antibiotic therapy has led to medical complications and emergence of multiresistant bacteria including Enterococcus faecalis. In this study,…”
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Insight into and Computational Studies of the Selective Synthesis of 6H‑Dibenzo[b,h]xanthenes by Carneiro, Paula F, Pinto, Maria do Carmo F. R, Marra, Roberta K. F, Campos, Vinícius R, Resende, Jackson Antônio L. C, Delarmelina, Maicon, Carneiro, José Walkimar M, Lima, Emerson S, da Silva, Fernando de C, Ferreira, Vitor F

“…Starting from 2-hydroxy-1,4-naphthoquinone (lawsone), we synthesized eight new 6H-dibenzo­[b,h]­xanthene derivatives selectively under solvent-free conditions…”
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Naphthoquinoidal [1,2,3]-triazole, a new structural moiety active against Trypanosoma cruzi by da Silva, Eufrânio N., Menna-Barreto, Rubem F.S., Pinto, Maria do Carmo F.R., Silva, Raphael S.F., Teixeira, Daniel V., de Souza, Maria Cecília B.V., De Simone, Carlos Alberto, De Castro, Solange L., Ferreira, Vitor F., Pinto, Antônio V.

“…[1,2,3]-Triazole derivatives of nor-β-lapachone were synthesized and assayed against the infective bloodstream trypomastigote form of Trypanosoma cruzi, the…”
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3-Arylamino and 3-Alkoxy-nor-β-lapachone Derivatives: Synthesis and Cytotoxicity against Cancer Cell Lines by da Silva Júnior, Eufrânio N, de Deus, Clara F, Cavalcanti, Bruno C, Pessoa, Cláudia, Costa-Lotufo, Letícia V, Montenegro, Raquel C, de Moraes, Manoel O, Pinto, Maria do Carmo F. R, de Simone, Carlos A, Ferreira, Vitor F, Goulart, Marilia O. F, Andrade, Carlos Kleber Z, Pinto, Antônio V

“…Several 3-arylamino and 3-alkoxy-nor-β-lapachone derivatives were synthesized in moderate to high yields and found to be highly potent against cancer cells…”
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1,3-Azoles from ortho-naphthoquinones: Synthesis of aryl substituted imidazoles and oxazoles and their potent activity against Mycobacterium tuberculosis by Moura, Kelly C.G., Carneiro, Paula F., Pinto, Maria do Carmo F.R., da Silva, José A., Malta, Valéria R.S., de Simone, Carlos A., Dias, Gleiston G., Jardim, Guilherme A.M., Cantos, Jéssica, Coelho, Tatiane S., da Silva, Pedro E. Almeida, da Silva, Eufrânio N.

“…Twenty-three naphthoimidazoles and six naphthoxazoles were synthesised and evaluated against susceptible and rifampicin- and isoniazid-resistant strains of…”
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The evaluation of quinonoid compounds against Trypanosoma cruzi: Synthesis of imidazolic anthraquinones, nor-β-lapachone derivatives and β-lapachone-based 1,2,3-triazoles by da Silva Júnior, Eufrânio N., Guimarães, Tiago T., Menna-Barreto, Rubem F.S., Pinto, Maria do Carmo F.R., de Simone, Carlos A., Pessoa, Claudia, Cavalcanti, Bruno C., Sabino, José R., Andrade, Carlos Kleber Z., Goulart, Marilia O.F., de Castro, Solange L., Pinto, Antônio V.

“…In continuation to our screening program of napththoquinones with activity against bloodstream trypomastigote forms of Trypanosoma cruzi, the etiological agent…”
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Synthesis and potent antitumor activity of new arylamino derivatives of nor-β-lapachone and nor-α-lapachone by da Silva Júnior, Eufrânio N., de Souza, Maria Cecília B.V., Pinto, Antônio V., Pinto, Maria do Carmo F.R., Goulart, Marilia O.F., Barros, Francisco W.A., Pessoa, Claudia, Costa-Lotufo, Letícia V., Montenegro, Raquel C., de Moraes, Manoel O., Ferreira, Vitor F.

“…Several arylamino derivatives of nor-β-lapachone and one derivative of nor-α-lapachone were synthesized in moderate to high yields and found to show very…”
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Quinonoid and phenazine compounds: Synthesis and evaluation against H37Rv, rifampicin and isoniazid-resistance strains of Mycobacterium tuberculosis by CARNEIRO, Paula F, PINTO, Maria Do Carmo F. R, DE MOURA, Kelly C. G, DA SILVA, Pedro A, DA SILVA JUNIOR, Eufranio N, COELHO, Tatiane S, CAVALCANTI, Bruno C, PESSOA, Cláudia, DE SIMONE, Carlos A, NUNES, Isabelle K. C, DE OLIVEIRA, Nathalia M, DE ALMEIDA, Renata G, PINTO, Antonio V

“…Several quinonoid and phenazine compounds were synthesized in moderate to high yields and showed activity against H(37)Rv, rifampicin and isoniazid-resistance…”
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Separation of New Naphthoxazole Derivatives of Lapachol by High-Speed Counter-Current Chromatography by Del Rio, Karina P., de Moura, Kelly C. G., Pinto, Maria do Carmo F. R., Leitão, Gilda G.

“…This work describes the use of high-speed counter-current chromatography as an efficient and economic method in the separation and purification of new…”
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A Trypanocidal Phenazine Derived from β-Lapachone by Neves-Pinto, Cleverson, Malta, Valéria R. S, Pinto, Maria do Carmo F. R, Santos, Regina H. A, de Castro, Solange L, Pinto, Antônio Ventura

“…An intensive effort has been directed toward finding alternative drugs for treatment of Chagas' disease, caused by Trypanosoma cruzi, and prophylaxis of blood…”
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A macrolactone from benzo[ a]phenazine with potent activity against Mycobacterium tuberculosis by Silva, Raphael S.F., Pinto, Maria do Carmo F.R., Goulart, Marília O.F., de Souza Filho, José D., Neves, Ivan, Lourenço, Maria Cristina S., Pinto, Antonio V.

“…We report here an alternative to the MCPBA or ozonolysis-based oxidation methods of quinoxaline-featuring compounds prepared from beta-lapachones. The use of…”
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Applications of counter-current chromatography in organic synthesis purification of heterocyclic derivatives of lapachol by Silva, Raphael S.F., Leitão, Gilda G., Brum, Thiago B., Lobato, Ana Paula G., Pinto, Maria do Carmo F.R., Pinto, Antonio V.

“…This work describes the application of counter-current chromatography (CCC) as a useful, fast and economic alternative for the isolation and purification of…”
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Trypanocidal activity of isolated naphthoquinones from Tabebuia and some heterocyclic derivatives: a review from an interdisciplinary study by De Moura, Kelly C. G., Emery, Flávio S., Neves-Pinto, Cleverson, Pinto, Maria do Carmo F. R., Dantas, Andrea P., Salomão, Kelly, Castro, Solange L. de, Pinto, Antônio V.

“…Naphthoquinones isolated from the wood of trees of the families Bignoniaceae and Verbenaceae have been subjected to an interdisciplinary study since the…”
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Synthesis and characterisation of a new polycyclic phenazine from 1,4-naphthoquinone by da Silva, Matuzalém J., Pinto, Maria do Carmo F.R., de Simone, Carlos A., Soares, Janaína G., Reys, José R. Machado, de Souza Filho, José D., Harrison, William T.A., Carvalho, Carlos E.M., Goulart, Marília O.F., da Silva Júnior, Eufrânio N., Pinto, Antonio V.

“…Bioactive naphthoquinone-derived heterocyclic compounds have been prepared. Herein, we describe the semisynthesis of a new phenazine, through modified Hooker’s…”
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Potent naphthoquinones against antimony-sensitive and -resistant Leishmania parasites: Synthesis of novel α- and nor-α-lapachone-based 1,2,3-triazoles by copper-catalyzed azide–alkyne cycloaddition by Guimarães, Tiago T., Pinto, Maria do Carmo F.R., Lanza, Juliane S., Melo, Maria N., do Monte-Neto, Rubens L., de Melo, Isadora M.M., Diogo, Emilay B.T., Ferreira, Vitor F., Camara, Celso A., Valença, Wagner O., de Oliveira, Ronaldo N., Frézard, Frédéric, da Silva Júnior, Eufrânio N.

“…Continuing our screening program for novel anti-parasite compounds, we synthesized seven 1,4-naphthoquinones coupled to 1,2,3-triazoles, five…”
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Synthesis and evaluation of quinonoid compounds against tumor cell lines by da Silva, Eufrânio N., Cavalcanti, Bruno C., Guimarães, Tiago T., Pinto, Maria do Carmo F.R., Cabral, Igor O., Pessoa, Cláudia, Costa-Lotufo, Letícia V., de Moraes, Manoel O., de Andrade, Carlos K.Z., dos Santos, Marcelo R., de Simone, Carlos A., Goulart, Marilia O.F., Pinto, Antonio V.

“…Thirty two compounds were synthesized in moderate to high yields and showed activity against cancer cells HL-60 (leukemia), MDA-MB435 (melanoma), HCT-8 (colon)…”
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Complete and unambiguous assignments of 1H and 13C chemical shifts of new arylamino derivatives of ortho-naphthofuranquinones by da Silva Júnior, Eufrânio N., de Souza, Maria Cecília B. V., Pinto, Antônio V., Pinto, Maria do Carmo F. R., Nogueira, Christiane M., Ferreira, Vitor F., Azeredo, Rodrigo B. V.

“…Six new nor‐β‐lapachones have been synthesized from reaction of 3‐bromo‐nor‐β‐lapachone with arylamines. These derivatives have potent anticancer properties…”
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Antimalarial activity of phenazines from lapachol, β-lapachone and its derivatives against Plasmodium falciparum in vitro and Plasmodium berghei in vivo by DE ANDRADE-NETO, Valter F, GOULART, Marilia O. F, DA SILVA, Jorge F, DA SILVA, Matuzalém J, PINTO, Maria Do Carmo F. R, PINTO, Antonio V, ZALIS, Mariano G, CARVALHO, Luzia H, KRETTLI, Antoniana U

“…The antimalarial activity of benzo[a]phenazines synthesized from 1,2-naphthoquinone, lapachol, beta-lapachone and several derivatives have been tested against…”
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