Search Results - "PIMPINELLI, Nicola"

Cellular Mechanisms in Acute and Chronic Wounds after PDT Therapy: An Update by Grandi, Vieri, Corsi, Alessandro, Pimpinelli, Nicola, Bacci, Stefano

“…PDT is a two-stage treatment that combines light energy with a photosensitizer designed to destroy cancerous and precancerous cells after light activation…”
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Tolerogenic IDO1 + CD83 - Langerhans Cells in Sentinel Lymph Nodes of Patients with Melanoma by Gerlini, Gianni, Di Gennaro, Paola, Pimpinelli, Nicola, Sestini, Serena, Borgognoni, Lorenzo

“…Langerhans cells (LCs) are crucial regulators of anti-cancer immune responses. Cancer, however, can alter DCs functions leading to tolerance. The enzyme…”
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EORTC, ISCL, and USCLC consensus recommendations for the treatment of primary cutaneous CD30-positive lymphoproliferative disorders: lymphomatoid papulosis and primary cutaneous anaplastic large-cell lymphoma by Kempf, Werner, Pfaltz, Katrin, Vermeer, Maarten H., Cozzio, Antonio, Ortiz-Romero, Pablo L., Bagot, Martine, Olsen, Elise, Kim, Youn H., Dummer, Reinhard, Pimpinelli, Nicola, Whittaker, Sean, Hodak, Emmilia, Cerroni, Lorenzo, Berti, Emilio, Horwitz, Steve, Prince, H. Miles, Guitart, Joan, Estrach, Teresa, Sanches, José A., Duvic, Madeleine, Ranki, Annamari, Dreno, Brigitte, Ostheeren-Michaelis, Sonja, Knobler, Robert, Wood, Gary, Willemze, Rein

“…Primary cutaneous CD30+ lymphoproliferative disorders (CD30+ LPDs) are the second most common form of cutaneous T-cell lymphomas and include lymphomatoid…”
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Revisions to the staging and classification of mycosis fungoides and Sézary syndrome: a proposal of the International Society for Cutaneous Lymphomas (ISCL) and the cutaneous lymphoma task force of the European Organization of Research and Treatment of Cancer (EORTC) by Olsen, Elise, Vonderheid, Eric, Pimpinelli, Nicola, Willemze, Rein, Kim, Youn, Knobler, Robert, Zackheim, Herschel, Duvic, Madeleine, Estrach, Teresa, Lamberg, Stanford, Wood, Gary, Dummer, Reinhard, Ranki, Annamari, Burg, Gunter, Heald, Peter, Pittelkow, Mark, Bernengo, Maria-Grazia, Sterry, Wolfram, Laroche, Liliane, Trautinger, Franz, Whittaker, Sean

“…The ISCL/EORTC recommends revisions to the Mycosis Fungoides Cooperative Group classification and staging system for cutaneous T-cell lymphoma (CTCL). These…”
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Novel Therapeutic Approaches and Targets for the Treatment of Atopic Dermatitis by Pescitelli, Leonardo, Rosi, Elia, Ricceri, Federica, Pimpinelli, Nicola, Prignano, Francesca

“…Atopic Dermatitis is one of the most common inflammatory skin diseases, with an estimated prevalence of 2.1-4.9% in adults. Recently, advances in Atopic…”
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Skin-directed therapy and biologic response modifiers in mycosis fungoides by Grandi, Vieri, Colantuono, Virginia Alba, Pimpinelli, Nicola

“…The most common and widespread type of cutaneous T-cell lymphoma is mycosis fungoides (MF), and it has a multiphasic clinical and biological course, with early…”
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HEDGEHOG-GLI Signaling Drives Self-Renewal and Tumorigenicity of Human Melanoma-Initiating Cells by Santini, Roberta, Vinci, Maria C., Pandolfi, Silvia, Penachioni, Junia Y., Montagnani, Valentina, Olivito, Biagio, Gattai, Riccardo, Pimpinelli, Nicola, Gerlini, Gianni, Borgognoni, Lorenzo, Stecca, Barbara

“…The question of whether cancer stem/tumor‐initiating cells (CSC/TIC) exist in human melanomas has arisen in the last few years. Here, we have used nonadherent…”
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Blastic Plasmacytoid Dendritic Cell Neoplasm: State of the Art and Prospects by Sapienza, Maria Rosaria, Pileri, Alessandro, Derenzini, Enrico, Melle, Federica, Motta, Giovanna, Fiori, Stefano, Calleri, Angelica, Pimpinelli, Nicola, Tabanelli, Valentina, Pileri, Stefano

“…Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is an extremely rare tumour, which usually affects elderly males and presents in the skin with frequent…”
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Endocrine-related adverse events in a large series of cancer patients treated with anti-PD1 therapy by Rubino, Rossella, Marini, Andrea, Roviello, Giandomenico, Presotto, Elena Margherita, Desideri, Isacco, Ciardetti, Isabella, Brugia, Marco, Pimpinelli, Nicola, Antonuzzo, Lorenzo, Mini, Enrico, Livi, Lorenzo, Maggi, Mario, Peri, Alessandro

“…Purpose Immune checkpoint inhibitors have opened a new scenario in the treatment of cancer. These agents can elicit adverse events, which may affect different…”
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TNM classification system for primary cutaneous lymphomas other than mycosis fungoides and Sézary syndrome: a proposal of the International Society for Cutaneous Lymphomas (ISCL) and the Cutaneous Lymphoma Task Force of the European Organization of Research and Treatment of Cancer (EORTC) by Kim, Youn H., Willemze, Rein, Pimpinelli, Nicola, Whittaker, Sean, Olsen, Elise A., Ranki, Annamari, Dummer, Reinhard, Hoppe, Richard T.

“…Currently availabel staging systems for non-Hodgkin lymphomas are not useful for clinical staging classification of most primary cutaneous lymphomas. The…”
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European Organization for Research and Treatment of Cancer and International Society for Cutaneous Lymphoma consensus recommendations for the management of cutaneous B-cell lymphomas by Senff, Nancy J., Noordijk, Evert M., Kim, Youn H., Bagot, Martine, Berti, Emilio, Cerroni, Lorenzo, Dummer, Reinhard, Duvic, Madeleine, Hoppe, Richard T., Pimpinelli, Nicola, Rosen, Steven T., Vermeer, Maarten H., Whittaker, Sean, Willemze, Rein

“…Primary cutaneous B-cell lymphomas (CBCL) represent approximately 20% to 25% of all primary cutaneous lymphomas. With the advent of the World Health…”
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New Screening Strategy Combining Anal Papanicolaou and Human Papillomavirus Tests for Human Papillomavirus–Related Anal Cancer: A Prospective, Single-Center Study by Pisano, Luigi, Grandi, Vieri, Tiradritti, Luana, Zuccati, Giuliano, Caminati, Filippo, Giani, Iacopo, Bisanzi, Simonetta, Matucci, Marzia, Carozzi, Francesca, Pimpinelli, Nicola, Elbetti, Claudio

“…Background The objective of this study was to evaluate the performance of a combined approach of liquid-based anal cytology and human papillomavirus (HPV)…”
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The never-ending story of mpox epidemic: Tracing a new cluster in Florence, Italy by Pisano, Luigi, Magliulo, Manfredi, Turco, Martina, Farini, Jacopo, Rapaccini, Anna Lisa, Lagi, Filippo, Bartoloni, Alessandro, Pimpinelli, Nicola

“…In line with this recent trend, we observed 17 new confirmed mpox cases between January and mid-February 2024 in Florence, Italy: 15 at the Sexually…”
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Effectiveness and tolerability of chlormethine gel for the management of mycosis fungoides: a multicenter real-life evaluation by Alberti-Violetti, Silvia, Ardigò, Marco, Massone, Cesare, Pileri, Alessandro, Sala, Raffaella, Teoli, Miriam, Grandi, Vieri, Quaglino, Pietro, Pimpinelli, Nicola, Berti, Emilio

“…Topical chlormethine (CL) is recommended as a first-line treatment for early-stage mycosis fungoides (MF) and in 2017, the European Medicines Agency approved…”
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Giant Primary Cutaneous Follicle Centre B-Cell Lymphoma by Corrà, Alberto, Ciardetti, Isabella, Gemignani, Andrea, Gherardi, Eleonora, Pimpinelli, Nicola, Grandi, Vieri

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Abscopal Effect After Localized Radiotherapy in a Patient With Sezary Syndrome Under Treatment with Mogamulizumab by Grandi, Vieri, Ciardetti, Isabella, Gemignani, Andrea, Gherardi, Eleonora, Grassi, Tommaso, Pimpinelli, Nicola

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Insights into the Pathogenesis of HS and Therapeutical Approaches by Rosi, Elia, Fastame, Maria Thais, Scandagli, Ilaria, Di Cesare, Antonella, Ricceri, Federica, Pimpinelli, Nicola, Prignano, Francesca

“…Hidradenitis suppurativa (HS) is a debilitating, chronic, (auto)inflammatory disease primarily affecting apocrine gland-rich areas of the body. Although…”
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Granular IgA Deposits in the Skin of Patients with Coeliac Disease: Is it Always Dermatitis Herpetiformis? by Bonciolini, Veronica, Antiga, Emiliano, Bianchi, Beatrice, Del Bianco, Elena, Ninci, Alessandra, Maio, Vincenza, Pimpinelli, Nicola, Caproni, Marzia

“…Coeliac disease is an immune-mediated enteropathy driven by gluten, which can be associated with dermatitis herpetiformis. The presence of granular IgA…”
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CD63 Tetraspanin Is a Negative Driver of Epithelial-to-Mesenchymal Transition in Human Melanoma Cells by Lupia, Antonella, Peppicelli, Silvia, Witort, Ewa, Bianchini, Francesca, Carloni, Vinicio, Pimpinelli, Nicola, Urso, Carmelo, Borgognoni, Lorenzo, Capaccioli, Sergio, Calorini, Lido, Lulli, Matteo

“…The CD63 tetraspanin is highly expressed in the early stages of melanoma and decreases in advanced lesions, suggesting it as a possible suppressor of tumor…”
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ALA-PDT exerts beneficial effects on chronic venous ulcers by inducing changes in inflammatory microenvironment, especially through increased TGF-beta release: A pilot clinical and translational study by Grandi, Vieri, Bacci, Stefano, Corsi, Alessandro, Sessa, Maurizio, Puliti, Elisa, Murciano, Nicoletta, Scavone, Francesca, Cappugi, Pietro, Pimpinelli, Nicola

“…•ALA-PDT seems safe and potentially effective in helping chronic venous wounds’ repair.•ALA-PDT is able to induce beneficial changes on inflammatory wounds…”
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