Search Results - "PILETTE, C."

Dendritic cells revisited in human allergic rhinitis and asthma by Froidure, A., Shen, C., Pilette, C.

“…The role of dendritic cells (DCs) in airway allergy has been studied for 15 years; recent data has highlighted the cross talk with airway epithelial cells and…”
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Chronic inflammatory airway diseases: the central role of the epithelium revisited by Gohy, S. T., Hupin, C., Pilette, C., Ladjemi, M. Z.

“…Summary The respiratory epithelium plays a critical role for the maintenance of airway integrity and defense against inhaled particles. Physical barrier…”
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Myeloid dendritic cells are primed in allergic asthma for thymic stromal lymphopoietin‐mediated induction of Th2 and Th9 responses by Froidure, A., Shen, C., Gras, D., Van Snick, J., Chanez, P., Pilette, C.

“…Background Type 1 myeloid dendritic cells (mDCs) contribute to inception of allergic asthma (AA) and are regulated by epithelial‐derived cytokines. Objectives…”
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The epithelial barrier and immunoglobulin A system in allergy by Carlier, F. M., Sibille, Y., Pilette, C.

“…Summary Airway and intestinal epithelial layers represent first‐line physical barriers, playing a key role in mucosal immunity. Barrier dysfunction,…”
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The role of allergen components for the diagnosis of latex‐induced occupational asthma by Vandenplas, O., Froidure, A., Meurer, U., Rihs, H.‐P., Rifflart, C., Soetaert, S., Jamart, J., Pilette, C., Raulf, M.

“…Background Recombinant Hevea brasiliensis (rHev b) natural rubber latex (NRL) allergen components have been developed to assess the patients’ allergen…”
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Features of mesenchymal transition in the airway epithelium from chronic rhinosinusitis by Hupin, C., Gohy, S., Bouzin, C., Lecocq, M., Polette, M., Pilette, C.

“…Background Chronic rhinosinusitis (CRS) defines a group of disorders characterized by persistent inflammation of the sinonasal tract. Epithelial changes and…”
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From the hygiene hypothesis to A20: the protective effect of endotoxins against asthma development by Froidure, A., Pilette, C.

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Chronic oral corticosteroids use and persistent eosinophilia in severe asthmatics from the Belgian severe asthma registry by Graff, S, Vanwynsberghe, S, Brusselle, G, Hanon, S, Sohy, C, Dupont, L J, Peche, R, Michils, A, Pilette, C, Joos, G, Louis, R E, Schleich, F N

“…Severe asthma (SA) may require frequent courses or chronic use of oral corticosteroids (OCS), inducing many known side effects and complications. Therefore, it…”
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Aberrant dendritic cell function conditions Th2‐cell polarization in allergic rhinitis by Pilette, C., Jacobson, M. R., Ratajczak, C., Detry, B., Banfield, G., VanSnick, J., Durham, S. R., Nouri‐Aria, K. T.

“…Background Myeloid (m) and plasmacytoid (p) dendritic cells (DCs) regulate immune responses to allergens, whereas it remains unclear whether abnormal DC…”
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FcεRI expression and IgE binding by dendritic cells and basophils in allergic rhinitis and upon allergen immunotherapy by Berings, M., Gevaert, P., De Ruyck, N., Derycke, L., Holtappels, G., Pilette, C., Bachert, C., Lambrecht, B. N., Dullaers, M.

“…Summary Background In humans, both basophils and dendritic cells (DCs) express the high‐affinity IgE receptor (FcεRI). Objective To gain more insight into the…”
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Sublingual grass pollen immunotherapy is associated with increases in sublingual Foxp3-expressing cells and elevated allergen-specific immunoglobulin G4, immunoglobulin A and serum inhibitory activity for immunoglobulin E-facilitated allergen binding to B cells by Scadding, G. W., Shamji, M. H., Jacobson, M. R., Lee, D. I., Wilson, D., Lima, M. T., Pitkin, L., Pilette, C., Nouri-Aria, K., Durham, S. R.

“…Summary Background The mechanisms of sublingual immunotherapy (SLIT) are less well understood than those of subcutaneous immunotherapy (SCIT). Objectives To…”
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Allergic hypersensitivity to topical and systemic corticosteroids: a review by Baeck, M., Marot, L., Nicolas, J.‐F., Pilette, C., Tennstedt, D., Goossens, A.

“…Corticosteroids, which are potent anti‐inflammatory and immunomodulator agents used in the treatment of various inflammatory diseases including allergic…”
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Impaired ICOSL in human myeloid dendritic cells promotes Th2 responses in patients with allergic rhinitis and asthma by Shen, C., Hupin, C., Froidure, A., Detry, B., Pilette, C.

“…Summary Background Myeloid dendritic cells (mDCs) and costimulatory molecules such as ICOSL/B7H2 play a pivotal role in murine experimental asthma, while…”
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Potential therapeutic implication of focal adhesion kinase in small-cell lung cancer by Decouvreur, C, Lecocq, M, Pilette, C, Aboubakar Nana, F, Ocak, S

“…The molecular steps leading to small cell lung cancer (SCLC) development and progression are still poorly understood, resulting in the absence of targeted…”
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“Real-life” effectiveness of omalizumab in patients with severe persistent allergic asthma: The PERSIST study by Brusselle, G, Michils, A, Louis, R, Dupont, L, Van de Maele, B, Delobbe, A, Pilette, C, Lee, C.S, Gurdain, S, Vancayzeele, S, Lecomte, P, Hermans, C, MacDonald, K, Song, M, Abraham, I

“…Summary Objective To evaluate the 16- and 52-week effectiveness of add-on omalizumab treatment under real-life heterogeneity in patients, settings, and…”
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Downregulation of polymeric immunoglobulin receptor and secretory IgA antibodies in eosinophilic upper airway diseases by Hupin, C., Rombaux, P., Bowen, H., Gould, H., Lecocq, M., Pilette, C.

“…Background Immunoglobulin (Ig) A represents a first‐line defence mechanism in the airways, but little is known regarding its implication in upper airway…”
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Heterogeneity of phenotypes in severe asthmatics. The Belgian Severe Asthma Registry (BSAR) by Schleich, F, Brusselle, G, Louis, R, Vandenplas, O, Michils, A, Pilette, C, Peche, R, Manise, M, Joos, G

“…Summary The Belgian severe asthma registry is a web-based registry encompassing demographic, clinical, functional and inflammatory data of severe asthmatics…”
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CCR4 ligands are up-regulated in the airways of atopic asthmatics after segmental allergen challenge by Pilette, C, Francis, J.N, Till, S.J, Durham, S.R

“…T-helper (Th) 2 cytokines are thought to mediate most features of allergic inflammation in atopic asthma. However, it remains unclear whether chemokine…”
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A Belgian survey on the diagnosis of asthma-COPD overlap syndrome by Cataldo, Didier, Corhay, Jean-Louis, Derom, Eric, Louis, Renaud, Marchand, Eric, Michils, Alain, Ninane, Vincent, Peché, Rudi, Pilette, Charles, Vincken, Walter, Janssens, Wim

“…Patients with chronic airway disease may present features of both asthma and COPD, commonly referred to as asthma-COPD overlap syndrome (ACOS). Recommendations…”
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Update on the roles of distal airways in COPD by Burgel, P-R, Bourdin, A, Chanez, P, Chabot, F, Chaouat, A, Chinet, T, de Blic, J, Devillier, P, Deschildre, A, Didier, A, Garcia, G, Jebrak, G, Laurent, F, Morel, H, Perez, T, Pilette, C, Roche, N, Tillie-Leblond, I, Verbanck, S, Dusser, D

“…This review is the summary of a workshop on the role of distal airways in chronic obstructive pulmonary disease (COPD), which took place in 2009 in Vence,…”
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