Search Results - "PIETRAS, R. J"

Antibody to HER-2/neu receptor blocks DNA repair after cisplatin in human breast and ovarian cancer cells by Pietras, R J, Fendly, B M, Chazin, V R, Pegram, M D, Howell, S B, Slamon, D J

“…Approximately 30% of human breast and ovarian cancers have amplification and/or overexpression of HER-2/neu gene which encodes a cell surface growth-factor…”
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Remission of human breast cancer xenografts on therapy with humanized monoclonal antibody to HER-2 receptor and DNA-reactive drugs by PIETRAS, R. J, PEGRAM, M. D, FINN, R. S, MANEVAL, D. A, SLAMON, D. J

“…HER-2 oncogene encodes a transmembrane growth factor receptor that is overexpressed in 25-30% of patients with primary breast and ovarian cancer. A murine…”
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The effect of HER-2/neu overexpression on chemotherapeutic drug sensitivity in human breast and ovarian cancer cells by PEGRAM, M. D, FINN, R. S, ARZOO, K, BERYT, M, PIETRAS, R. J, SLAMON, D. J

“…Recent studies indicate that oncogenes may be involved in determining the sensitivity of human cancers to chemotherapeutic agents. To define the effect of…”
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Biologic effects of heregulin/neu differentiation factor on normal and malignant human breast and ovarian epithelial cells by AGUILAR, Z, AKITA, R. W, FINN, R. S, RAMOS, B. L, PEGRAM, M. D, KABBINAVAR, F. F, PIETRAS, R. J, PISACANE, P, SLIWKOWSKI, M. X, SLAMON, D. J

“…The heregulins are a family of ligands with ability to induce phosphorylation of the p185HER-2/neu receptor. Various investigators have reported a variety of…”
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Steroid hormone receptors in target cell membranes by Pietras, R J, Nemere, I, Szego, C M

“…Numerous reports of rapid steroid hormone effects in diverse cell types cannot be explained by the generally prevailing theory that centers on the activity of…”
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Membrane-associated binding sites for estrogen contribute to growth regulation of human breast cancer cells by MARQUEZ, Diana C, PIETRAS, Richard J

“…Membrane-associated binding sites for estrogen may mediate rapid effects of estradiol-17beta that contribute to proliferation of human breast cancers. After…”
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Monoclonal Antibody to HER-2/neu Receptor Modulates Repair of Radiation-induced DNA Damage and Enhances Radiosensitivity of Human Breast Cancer Cells Overexpressing This Oncogene by Pietras, R J, Poen, J C, Gallardo, D, Wongvipat, P N, Lee, HJ, Slamon, D J

“…The management of human breast cancer frequently includes radiation therapy as an important intervention, and improvement in the clinical efficacy of radiation…”
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Estrogen-signaling pathways in lung cancer by Márquez-Garbán, D C, Pietras, R J

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Urolithiasis update: clinical experience with the Swiss LithoClast by Schock, J, Barsky, R I, Pietras, J R

“…This article describes the authors' first experience using the EMS Swiss LithoClast pneumatic lithotriptor in the management of middle and distal ureteral…”
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Partial purification and characterization of oestrogen receptors in subfractions of hepatocyte plasma membranes by Pietras, R J, Szego, C M

“…To assess the subcellular distribution of oestrogen-binding components in their native state, plasma membrane and other cell fractions were prepared from…”
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Cell membrane estrogen receptors resurface by Pietras, Richard J, Szego, Clara M

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Wegener's granulomatosis with ureteric obstruction by Adelizzi, R A, Shockley, F K, Pietras, J R

“…Other than renal involvement, the urologic manifestations of Wegener's granulomatosis are relatively rare. A case of Wegener's is presented with both ureteric…”
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Epidermal growth factor receptor and tyrosine phosphorylation of estrogen receptor by Márquez, D C, Lee, J, Lin, T, Pietras, R J

“…Activation of estrogen receptor-alpha (ERalpha) by growth factors in the absence of estrogen is a well-documented phenomenon. To study further this process of…”
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Cathepsin B-like enzymes. Subcellular distribution and properties in neoplastic and control cells from human ectocervix by Pietras, R J, Roberts, J A

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The effects of cycle length on cardiac refractory periods in man by Denes, P, Wu, D, Dhingra, R, Pietras, R J, Rosen, K M

“…The effects of pacing-induced changes in cycle length on the refractory periods of the atrium, A-V node and His-Purkinje system were studied in 24 patients…”
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Lysosomal cathepsin B-like activity: mobilization in prereplicative and neoplastic epithelial cells by Pietras, RJ, Szego, CM, Roberts, JA, Seeler, BJ

“…Extracellular release of acid thiol proteinase activity by prereplicative and neoplastic epithelial cells was studied in serum-free, chemically defined media…”
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THE TOTAL WORK OF BREATHING IN NORMAL AND OBESE MEN by SHARP, J T, HENRY, J P, SWEANY, S K, MEADOWS, W R, PIETRAS, R J

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Estrogen-Induced Membrane Alterations and Growth Associated with Proteinase Activity in Endometrial Cells by Pietras, Richard J., Szego, Clara M.

“…Endometrial cells isolated from uteri of ovariectomized rats were treated in vitro with 1× 10-9M estradiol-17 β ( E2β ) to analyze early changes in membrane…”
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A characteristic precordial repolarization abnormality with intermittent left bundle-branch block by Denes, P, Pick, A, Miller, R H, Pietras, R J, Rosen, K M

“…We reviewed electrocardiograms of 23 patients with intermittent left bundle-branch block. A characteristic electrocardiographic pattern consisting of right and…”
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Comparative angiographic right and left ventricular volumes by Pietras, R J, Kondos, G T, Kaplan, D, Lam, W

“…Comparative angiographic right and left ventricular volumes and right and left ventricular ejection fractions have been reported in the same normal infants and…”
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