Search Results - "PIERSON, A. Scott"

A phase I and pharmacokinetic study of silybin-phytosome in prostate cancer patients by Flaig, Thomas W, Gustafson, Daniel L, Su, Lih-Jen, Zirrolli, Joseph A, Crighton, Frances, Harrison, Gail S, Pierson, A Scott, Agarwal, Rajesh, Glodé, L Michael

“…Silibinin is a polyphenolic flavonoid isolated from milk thistle with anti-neoplastic activity in several in vitro and in vivo models of cancer, including…”
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A Phase I and Pharmacokinetic Study of Exisulind and Docetaxel in Patients with Advanced Solid Tumors by WITTA, Samir E, GUSTAFSON, Daniel L, LONG, Michael E, GIBBS, Amy, KELLY, Karen, BUNN, Paul A, CHAN, Daniel C, PALLANSCH, Patrick, ECKHARDT, S. Gail, PIERSON, A. Scott, MENTER, Alexander, HOLDEN, Scott N, BASCHE, Michele, PERSKY, Martha, O'BRYANT, Cindy L, CHAN ZENG, BARON, Anna

“…Purpose: Exisulind (sulindac sulfone, FGN-1, Aptosyn) is a sulindac metabolite that induces apoptosis via inhibition of cyclic GMP-phosphodiesterase. This…”
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Analysis of docetaxel pharmacokinetics in humans with the inclusion of later sampling time-points afforded by the use of a sensitive tandem LCMS assay by GUSTAFSON, Daniel L, LONG, Michael E, ZIRROLLI, Joseph A, DUNCAN, Mark W, HOLDEN, Scott N, PIERSON, A. Scott, ECKHARDT, S. Gail

“…Docetaxel is a semisynthetic taxane derived from the needles of the European yew ( Taxus baccata) and it is an important chemotherapeutic agent in the…”
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A phase I study of bortezomib, etoposide and carboplatin in patients with advanced solid tumors refractory to standard therapy by Lieu, Christopher, Chow, Laura, Pierson, A. Scott, Eckhardt, S. Gail, O’Bryant, Cindy L., Morrow, Mark, Tran, Zung Vu, Wright, John J., Gore, Lia

“…Summary Purpose: To evaluate the toxicity, pharmacological, and biological properties of the combination of bortezomib, etoposide, and carboplatin in adults…”
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Angiogenesis inhibitors in clinical development for lung cancer by Herbst, Roy S, Hidalgo, Manuel, Pierson, A.Scott, Holden, Scott N, Bergen, Michael, Eckhardt, S.Gail

“…The use of tumor angiogenesis as a therapeutic target is based on extensive literature showing the dependence of tumors on the process of angiogenesis for…”
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A phase II study of Irofulven (MGI 114) in patients with stage IV melanoma by PIERSON, A. Scott, GIBBS, Peter, RICHARDS, Jon, RUSS, Paul, ECKHARDT, S. Gail, GONZALEZ, Rene

“…Sixteen patients with stage IV melanoma, who were heavily pretreated, received 11 mg/m2/day of intravenous Irofulven for five consecutive days every 28 days…”
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Therapeutic angiogenesis inhibitors in the treatment of cancer by Hidalgo, M, Pierson, A S, Holden, S N, Bergen, M, Eckhardt, S G

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