Search Results - "PIERI, Lisa"

Impact of calreticulin mutations on clinical and hematological phenotype and outcome in essential thrombocythemia by Rotunno, Giada, Mannarelli, Carmela, Guglielmelli, Paola, Pacilli, Annalisa, Pancrazzi, Alessandro, Pieri, Lisa, Fanelli, Tiziana, Bosi, Alberto, Vannucchi, Alessandro M.

“…Mutations in the calreticulin (CALR) gene were recently discovered in patients with essential thrombocythemia (ET) lacking the JAK2V617F and MPLW515 mutations,…”
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Long-term survival and blast transformation in molecularly annotated essential thrombocythemia, polycythemia vera, and myelofibrosis by Tefferi, Ayalew, Guglielmelli, Paola, Larson, Dirk R., Finke, Christy, Wassie, Emnet A., Pieri, Lisa, Gangat, Naseema, Fjerza, Rajmonda, Belachew, Alem A., Lasho, Terra L., Ketterling, Rhett P., Hanson, Curtis A., Rambaldi, Alessandro, Finazzi, Guido, Thiele, Juergen, Barbui, Tiziano, Pardanani, Animesh, Vannucchi, Alessandro M.

“…Janus kinase 2 (JAK2) mutations define polycythemia vera (PV). Calreticulin (CALR) and myeloproliferative leukemia virus oncogene (MPL) mutations are specific…”
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Clinical effect of driver mutations of JAK2, CALR, or MPL in primary myelofibrosis by Rumi, Elisa, Pietra, Daniela, Pascutto, Cristiana, Guglielmelli, Paola, Martínez-Trillos, Alejandra, Casetti, Ilaria, Colomer, Dolors, Pieri, Lisa, Pratcorona, Marta, Rotunno, Giada, Sant'Antonio, Emanuela, Bellini, Marta, Cavalloni, Chiara, Mannarelli, Carmela, Milanesi, Chiara, Boveri, Emanuela, Ferretti, Virginia, Astori, Cesare, Rosti, Vittorio, Cervantes, Francisco, Barosi, Giovanni, Vannucchi, Alessandro M., Cazzola, Mario

“…We studied the impact of driver mutations of JAK2, CALR, (calreticulin gene) or MPL on clinical course, leukemic transformation, and survival of patients with…”
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Ruxolitinib for essential thrombocythemia refractory to or intolerant of hydroxyurea: long-term phase 2 study results by Verstovsek, Srdan, Passamonti, Francesco, Rambaldi, Alessandro, Barosi, Giovanni, Rumi, Elisa, Gattoni, Elisabetta, Pieri, Lisa, Zhen, Huiling, Granier, Muriel, Assad, Albert, Cazzola, Mario, Kantarjian, Hagop M., Barbui, Tiziano, Vannucchi, Alessandro M.

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Impact of ruxolitinib on the natural history of primary myelofibrosis: a comparison of the DIPSS and the COMFORT-2 cohorts by Passamonti, Francesco, Maffioli, Margherita, Cervantes, Francisco, Vannucchi, Alessandro Maria, Morra, Enrica, Barbui, Tiziano, Caramazza, Domenica, Pieri, Lisa, Rumi, Elisa, Gisslinger, Heinz, Knoops, Laurent, Kiladjian, Jean Jaques, Mora, Barbara, Hollaender, Norbert, Pascutto, Cristiana, Harrison, Claire, Cazzola, Mario

“…The international prognostic scoring system (IPSS) provides reliable risk assessment in patients with primary myelofibrosis (PMF). Recent clinical trials in…”
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Epidemiology and clinical relevance of mutations in postpolycythemia vera and postessential thrombocythemia myelofibrosis: A study on 359 patients of the AGIMM group by Rotunno, Giada, Pacilli, Annalisa, Artusi, Valentina, Rumi, Elisa, Maffioli, Margherita, Delaini, Federica, Brogi, Giada, Fanelli, Tiziana, Pancrazzi, Alessandro, Pietra, Daniela, Bernardis, Isabella, Belotti, Clara, Pieri, Lisa, Sant'Antonio, Emanuela, Salmoiraghi, Silvia, Cilloni, Daniela, Rambaldi, Alessandro, Passamonti, Francesco, Barbui, Tiziano, Manfredini, Rossella, Cazzola, Mario, Tagliafico, Enrico, Vannucchi, Alessandro M., Guglielmelli, Paola

“…Transformation to secondary myelofibrosis (MF) occurs as part of the natural history of polycythemia vera (PPV‐MF) and essential thrombocythemia (PET‐MF)…”
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The effect of arterial hypertension on thrombosis in low‐risk polycythemia vera by Barbui, Tiziano, Vannucchi, Alessandro M., Carobbio, Alessandra, Rumi, Elisa, Finazzi, Guido, Gisslinger, Heinz, Ruggeri, Marco, Randi, Maria Luigia, Cazzola, Mario, Rambaldi, Alessandro, Gisslinger, Bettina, Pieri, Lisa, Thiele, Juergen, Pardanani, Animesh, Tefferi, Ayalew

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Genome integrity of myeloproliferative neoplasms in chronic phase and during disease progression by Klampfl, Thorsten, Harutyunyan, Ashot, Berg, Tiina, Gisslinger, Bettina, Schalling, Martin, Bagienski, Klaudia, Olcaydu, Damla, Passamonti, Francesco, Rumi, Elisa, Pietra, Daniela, Jäger, Roland, Pieri, Lisa, Guglielmelli, Paola, Iacobucci, Ilaria, Martinelli, Giovanni, Cazzola, Mario, Vannucchi, Alessandro M., Gisslinger, Heinz, Kralovics, Robert

“…Philadelphia chromosome–negative myeloproliferative neoplasms (MPNs) are clonal myeloid disorders with increased production of terminally differentiated cells…”
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Masked polycythemia Vera (mPV): Results of an international study by Barbui, Tiziano, Thiele, Jürgen, Gisslinger, Heinz, Finazzi, Guido, Carobbio, Alessandra, Rumi, Elisa, Luigia Randi, Maria, Betozzi, Irene, Vannucchi, Alessandro M., Pieri, Lisa, Carrai, Valentina, Gisslinger, Bettina, Müllauer, Leonhard, Ruggeri, Marco, Rambaldi, Alessandro, Tefferi, Ayalew

“…We examined the baseline features and clinical outcomes of 140 patients presenting with JAK2V617F positivity and a bone marrow morphology conforming with WHO…”
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Initial bone marrow reticulin fibrosis in polycythemia vera exerts an impact on clinical outcome by Barbui, Tiziano, Thiele, Jürgen, Passamonti, Francesco, Rumi, Elisa, Boveri, Emanuela, Randi, Maria Luigia, Bertozzi, Irene, Marino, Filippo, Vannucchi, Alessandro M., Pieri, Lisa, Rotunno, Giada, Gisslinger, Heinz, Gisslinger, Bettina, Müllauer, Leonhard, Finazzi, Guido, Carobbio, Alessandra, Gianatti, Andrea, Ruggeri, Marco, Nichele, Ilaria, D'Amore, Emanuele, Rambaldi, Alessandro, Tefferi, Ayalew

“…We examined the prevalence and prognostic relevance of bone marrow reticulin fibrosis in 526 patients with World Health Organization–defined polycythemia vera…”
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Recurrent thrombosis in patients with polycythemia vera and essential thrombocythemia: incidence, risk factors, and effect of treatments by De Stefano, Valerio, Za, Tommaso, Rossi, Elena, Vannucchi, Alessandro M, Ruggeri, Marco, Elli, Elena, Mico, Caterina, Tieghi, Alessia, Cacciola, Rossella R, Santoro, Cristina, Gerli, Giancarla, Vianelli, Nicola, Guglielmelli, Paola, Pieri, Lisa, Scognamiglio, Francesca, Rodeghiero, Francesco, Pogliani, Enrico M, Finazzi, Guido, Gugliotta, Luigi, Marchioli, Roberto, Leone, Giuseppe, Barbui, Tiziano, GIMEMA CMD-Working Party

“…1 Institute of Hematology, Catholic University, Rome 2 Dept. of Hematology, University of Florence, Florence 3 Hematology Department and Hemophilia and…”
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Prognostic impact of bone marrow fibrosis in primary myelofibrosis. A study of the AGIMM group on 490 patients by Guglielmelli, Paola, Rotunno, Giada, Pacilli, Annalisa, Rumi, Elisa, Rosti, Vittorio, Delaini, Federica, Maffioli, Margherita, Fanelli, Tiziana, Pancrazzi, Alessandro, Pieri, Lisa, Fjerza, Rajmonda, Pietra, Daniela, Cilloni, Daniela, Sant'Antonio, Emanuela, Salmoiraghi, Silvia, Passamonti, Francesco, Rambaldi, Alessandro, Barosi, Giovanni, Barbui, Tiziano, Cazzola, Mario, Vannucchi, Alessandro M.

“…The prognostic significance of bone marrow (BM) fibrosis grade in patients with primary myelofibrosis (PMF) is still debated. A fibrosis grade greater than 1…”
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Real-World Efficacy and Safety of Plasma-Derived Von Willebrand Factor-Containing Factor VIII Concentrates in Patients With Von Willebrand Disease in Italy by Federici, Augusto B, Santoro, Rita Carlotta, Santoro, Cristina, Pieri, Lisa, Santi, Roberto Mario, Barillari, Giovanni, Borchiellini, Alessandra, Tosetto, Alberto, Zanon, Ezio, De Cristofaro, Raimondo, Mairal, Esther, Mir, Roser

“…Plasma-derived von Willebrand factor-containing factor VIII concentrates (pd-VWF/FVIII-C) are the mainstay of treatment in von Willebrand disease (VWD)…”
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Increased Risk of Lymphoid Neoplasms in Patients with Philadelphia Chromosome–Negative Myeloproliferative Neoplasms by VANNUCCHI, Alessandro M, MASALA, Giovanna, PONZIANI, Vanessa, PANCRAZZI, Alessandro, ANNUNZIATO, Francesco, BOSI, Alberto, ANTONIOLI, Elisabetta, CHIARA SUSINI, Maria, GUGLIELMELLI, Paola, PIERI, Lisa, MAGGI, Laura, CAINI, Saverio, PALLI, Domenico, BOGANI, Costanza

“…Association of myeloproliferative neoplasm (MPN) with lymphoproliferative neoplasm (LPN) has been occasionally reported. The aim of this study, which included…”
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Frequent deletions of JARID2 in leukemic transformation of chronic myeloid malignancies by Puda, Ana, Milosevic, Jelena D., Berg, Tiina, Klampfl, Thorsten, Harutyunyan, Ashot S., Gisslinger, Bettina, Rumi, Elisa, Pietra, Daniela, Malcovati, Luca, Elena, Chiara, Doubek, Michael, Steurer, Michael, Tosic, Natasa, Pavlovic, Sonja, Guglielmelli, Paola, Pieri, Lisa, Vannucchi, Alessandro M., Gisslinger, Heinz, Cazzola, Mario, Kralovics, Robert

“…Chronic myeloproliferative neoplasms (MPN) and myelodysplastic syndromes (MDS) have an inherent tendency to progress to acute myeloid leukemia (AML). Using…”
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Infrequent occurrence of mutations in the PH domain of LNK in patients with JAK2 mutation-negative 'idiopathic' erythrocytosis by Spolverini, Ambra, Pieri, Lisa, Guglielmelli, Paola, Pancrazzi, Alessandro, Fanelli, Tiziana, Paoli, Chiara, Bosi, Alberto, Nichele, Ilaria, Ruggeri, Marco, Vannucchi, Alessandro M

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The JAK2V617 mutation induces constitutive activation and agonist hypersensitivity in basophils from patients with polycythemia vera by PIERI, Lisa, BOGANI, Costanza, GUGLIELMELL, Paola, ZINGARIELLO, Maria, ALBA RANA, Rosa, BARTALUCCI, Niccolò, BOSI, Alberto, VANNUCCHI, Alessandro M

“…The JAK2V617F mutation has been associated with constitutive and enhanced activation of neutrophils, while no information is available concerning other…”
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Hydroxyurea does not appreciably reduce JAK2 V617F allele burden in patients with polycythemia vera or essential thrombocythemia by ANTONIOLI, Elisabetta, CAROBBIO, Alessandra, RAMBALDI, Alessandro, BARBUI, Tiziano, VANNUCCHI, Alessandro M, PIERI, Lisa, PANCRAZZI, Alessandro, GUGLIELMELLI, Paola, DELAINI, Federica, PONZIANI, Vanessa, BARTALUCCI, Niccolò, TOZZI, Lorenzo, BOSI, Alberto

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Tetraspanin CD9 participates in dysmegakaryopoiesis and stromal interactions in primary myelofibrosis by Desterke, Christophe, Martinaud, Christophe, Guerton, Bernadette, Pieri, Lisa, Bogani, Costanza, Clay, Denis, Torossian, Frederic, Lataillade, Jean-Jacques, Hasselbach, Hans C, Gisslinger, Heinz, Demory, Jean-Loup, Dupriez, Brigitte, Boucheix, Claude, Rubinstein, Eric, Amsellem, Sophie, Vannucchi, Alessandro M, Le Bousse-Kerdilès, Marie-Caroline

“…Primary myelofibrosis is characterized by clonal myeloproliferation, dysmegakaryopoiesis, extramedullary hematopoiesis associated with myelofibrosis and…”
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Complex patterns of chromosome 11 aberrations in myeloid malignancies target CBL, MLL, DDB1 and LMO2 by Klampfl, Thorsten, Milosevic, Jelena D, Puda, Ana, Schönegger, Andreas, Bagienski, Klaudia, Berg, Tiina, Harutyunyan, Ashot S, Gisslinger, Bettina, Rumi, Elisa, Malcovati, Luca, Pietra, Daniela, Elena, Chiara, Della Porta, Matteo Giovanni, Pieri, Lisa, Guglielmelli, Paola, Bock, Christoph, Doubek, Michael, Dvorakova, Dana, Suvajdzic, Nada, Tomin, Dragica, Tosic, Natasa, Racil, Zdenek, Steurer, Michael, Pavlovic, Sonja, Vannucchi, Alessandro M, Cazzola, Mario, Gisslinger, Heinz, Kralovics, Robert

“…Exome sequencing of primary tumors identifies complex somatic mutation patterns. Assignment of relevance of individual somatic mutations is difficult and poses…”
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