Search Results - "PIERCE, J"

Comprehensive AAV capsid fitness landscape reveals a viral gene and enables machine-guided design by Ogden, Pierce J, Kelsic, Eric D, Sinai, Sam, Church, George M

“…Adeno-associated virus (AAV) capsids can deliver transformative gene therapies, but our understanding of AAV biology remains incomplete. We generated the…”
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Deep diversification of an AAV capsid protein by machine learning by Bryant, Drew H., Bashir, Ali, Sinai, Sam, Jain, Nina K., Ogden, Pierce J., Riley, Patrick F., Church, George M., Colwell, Lucy J., Kelsic, Eric D.

“…Modern experimental technologies can assay large numbers of biological sequences, but engineered protein libraries rarely exceed the sequence diversity of…”
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Cosmic rays, aerosols, clouds, and climate: Recent findings from the CLOUD experiment by Pierce, J. R.

“…The Cosmics Leaving OUtdoor Droplets (CLOUD) experiment was created to systematically test the link between galactic cosmic rays (GCR) and climate,…”
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Large contribution of natural aerosols to uncertainty in indirect forcing by Carslaw, K. S., Lee, L. A., Reddington, C. L., Pringle, K. J., Rap, A., Forster, P. M., Mann, G. W., Spracklen, D. V., Woodhouse, M. T., Regayre, L. A., Pierce, J. R.

“…The effect of anthropogenic aerosols on cloud droplet concentrations and radiative properties is the source of one of the largest uncertainties in the…”
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Estimate of the total carbon footprint and component carbon sources of different modes of labour analgesia by Pearson, F., Sheridan, N., Pierce, J. M. T.

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Carbon footprint of inhalational and total intravenous anaesthesia for paediatric anaesthesia: a modelling study by Narayanan, Hrishi, Raistrick, Christopher, Tom Pierce, J M, Shelton, Clifford

“…Tackling the climate emergency is now a key target for the healthcare sector. Avoiding inhalational anaesthesia is often cited as an important element of…”
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HDAC8: a multifaceted target for therapeutic interventions by Chakrabarti, Alokta, Oehme, Ina, Witt, Olaf, Oliveira, Guilherme, Sippl, Wolfgang, Romier, Christophe, Pierce, Raymond J, Jung, Manfred

“…Highlights • HDAC8, a unique class I HDAC, recognizes both histone and nonhistone substrates. • HDAC8 is implicated in cancer, schistosomiasis, and Cornelia de…”
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Not Taking New Patients by Pierce, Jr, J Rush

“…Pierce Jr. shares his experience of relieving his guilt from not accepting new patients. He mentions that in his fifth year of practice, he had mostly lost the…”
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The Family Meeting by Pierce, J. Rush

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Regeneration of Ammonia Borane Spent Fuel by Direct Reaction with Hydrazine and Liquid Ammonia by Sutton, Andrew D., Burrell, Anthony K., Dixon, David A., Garner, Edward B., Gordon, John C., Nakagawa, Tessui, Ott, Kevin C., Robinson, J. Pierce, Vasiliu, Monica

“…Ammonia borane (H₃N-BH₃, AB) is a lightweight material containing a high density of hydrogen (H₂) that can be readily liberated for use in fuel cell—powered…”
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The radio properties of high-excitation radio galaxies with intermediate radio powers by Pierce, J C S, Tadhunter, C N, Morganti, R

“…ABSTRACT In the past decade, high-sensitivity radio surveys have revealed that the local radio active galactic nucleus population is dominated by…”
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The magnitude and causes of uncertainty in global model simulations of cloud condensation nuclei by Lee, L. A, Pringle, K. J, Reddington, C. L, Mann, G. W, Stier, P, Spracklen, D. V, Pierce, J. R, Carslaw, K. S

“…Aerosol–cloud interaction effects are a major source of uncertainty in climate models so it is important to quantify the sources of uncertainty and thereby…”
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Tamoxifen Metabolite Concentrations, CYP2D6 Genotype, and Breast Cancer Outcomes by Madlensky, L, Natarajan, L, Tchu, S, Pu, M, Mortimer, J, Flatt, SW, Nikoloff, DM, Hillman, G, Fontecha, MR, Lawrence, HJ, Parker, BA, Wu, AHB, Pierce, JP

“…We explored whether breast cancer outcomes are associated with endoxifen and other metabolites of tamoxifen and examined potential correlates of endoxifen…”
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Defining osteoblast and adipocyte lineages in the bone marrow by Pierce, J.L., Begun, D.L., Westendorf, J.J., McGee-Lawrence, M.E.

“…Bone is a complex endocrine organ that facilitates structural support, protection to vital organs, sites for hematopoiesis, and calcium homeostasis. The bone…”
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Doctors need an environmental rating system for drugs by Pierce, J M Tom, Bourton, Laurence

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Uncertainty in global CCN concentrations from uncertain aerosol nucleation and primary emission rates by Pierce, J. R., Adams, P. J.

“…The indirect effect of aerosols on climate is highly uncertain and limits our ability to assess anthropogenic climate change. The foundation of this…”
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"The Action Level®" by Pierce, J. Thomas

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Twelve‐year trend in nitrous oxide use at a tertiary institution: striving for a net zero NHS by Elliott, K. J., Pierce, J. M. T.

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Do AGN triggering mechanisms vary with radio power? – I. Optical morphologies of radio-intermediate HERGs by Pierce, J C S, Tadhunter, C N, Ramos Almeida, C, Bessiere, P S, Rose, M

“…ABSTRACT Active galactic nuclei (AGNs) with intermediate radio powers are capable of driving multiphase outflows in galaxy bulges, and are also more common…”
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Management of Hereditary Breast Cancer: American Society of Clinical Oncology, American Society for Radiation Oncology, and Society of Surgical Oncology Guideline by Tung, Nadine M, Boughey, Judy C, Pierce, Lori J, Robson, Mark E, Bedrosian, Isabelle, Dietz, Jill R, Dragun, Anthony, Gelpi, Judith Balmana, Hofstatter, Erin W, Isaacs, Claudine J, Jatoi, Ismail, Kennedy, Elaine, Litton, Jennifer K, Mayr, Nina A, Qamar, Rubina D, Trombetta, Mark G, Harvey, Brittany E, Somerfield, Mark R, Zakalik, Dana

“…To develop recommendations for management of patients with breast cancer (BC) with germline mutations in BC susceptibility genes. The American Society of…”
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