Search Results - "PIEGARI, Elena"

Cardioprotective effects of miR-34a silencing in a rat model of doxorubicin toxicity by Piegari, Elena, Cozzolino, Anna, Ciuffreda, Loreta Pia, Cappetta, Donato, De Angelis, Antonella, Urbanek, Konrad, Rossi, Francesco, Berrino, Liberato

“…Cardiotoxicity remains a serious problem in anthracycline-treated oncologic patients. Therapeutic modulation of microRNA expression is emerging as a…”
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SIRT1 activation attenuates diastolic dysfunction by reducing cardiac fibrosis in a model of anthracycline cardiomyopathy by Cappetta, Donato, Esposito, Grazia, Piegari, Elena, Russo, Rosa, Ciuffreda, Loreta Pia, Rivellino, Alessia, Berrino, Liberato, Rossi, Francesco, De Angelis, Antonella, Urbanek, Konrad

“…Abstract Background Doxorubicin (DOXO) is an effective anti-neoplastic drug but its clinical benefits are hampered by cardiotoxicity. Oxidative stress,…”
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Anthracycline Cardiomyopathy Is Mediated by Depletion of the Cardiac Stem Cell Pool and Is Rescued by Restoration of Progenitor Cell Function by DE ANGELIS, Antonella, PIEGARI, Elena, URBANEK, Konrad, KAJSTURA, Jan, LERI, Annarosa, ROSSI, Francesco, ANVERSA, Piero, CAPPETTA, Donato, MARINO, Laura, FILIPPELLI, Amelia, BERRINO, Liberato, FERREIRA-MARTINS, Joao, HANQIAO ZHENG, HOSODA, Toru, ROTA, Marcello

“…Anthracyclines are the most effective drugs available in the treatment of neoplastic diseases; however, they have profound consequences on the structure and…”
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Intratracheal Administration of Mesenchymal Stem Cells Modulates Tachykinin System, Suppresses Airway Remodeling and Reduces Airway Hyperresponsiveness in an Animal Model by Urbanek, Konrad, De Angelis, Antonella, Spaziano, Giuseppe, Piegari, Elena, Matteis, Maria, Cappetta, Donato, Esposito, Grazia, Russo, Rosa, Tartaglione, Gioia, De Palma, Raffaele, Rossi, Francesco, D'Agostino, Bruno

“…The need for new options for chronic lung diseases promotes the research on stem cells for lung repair. Bone marrow-derived mesenchymal stem cells (MSCs) can…”
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Can Brain-Derived Neurotrophic Factor Be Considered a Biomarker for Bipolar Disorder? An Analysis of the Current Evidence by De Felice, Gianmarco, Luciano, Mario, Boiano, Alessia, Colangelo, Giulia, Catapano, Pierluigi, Della Rocca, Bianca, Lapadula, Maria Vita, Piegari, Elena, Toni, Claudia, Fiorillo, Andrea

“…Brain-derived neurotrophic factor (BDNF) plays a key role in brain development, contributing to neuronal survival and neuroplasticity. Previous works have…”
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Expression of MMP-2, MMP-9, and NGAL in Tissue and Serum of Patients with Vascular Aneurysms and Their Modulation by Statin Treatment: A Pilot Study by Cione, Erika, Piegari, Elena, Gallelli, Giuseppe, Caroleo, Maria Cristina, Lamirata, Elena, Curcio, Francesca, Colosimo, Federica, Cannataro, Roberto, Ielapi, Nicola, Colosimo, Manuela, Franciscis, Stefano de, Gallelli, Luca

“…Matrix metalloproteinases (MMPs) are involved in vascular wall degradation, and drugs able to modulate MMP activity can be used to prevent or treat aneurysmal…”
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Lung Mesenchymal Stem Cells Ameliorate Elastase-Induced Damage in an Animal Model of Emphysema by Sgambato, Manuela, Rossi, Francesco, Berrino, L., Urbanek, Konrad, D’Agostino, Bruno, Liparulo, Angela, Ciuffreda, Loreta Pia, Esposito, Grazia, Piegari, Elena, Tartaglione, Gioia, Spaziano, Giuseppe, De Angelis, A., Cappetta, Donato, Russo, Teresa Palmira

“…Pulmonary emphysema is a respiratory condition characterized by alveolar destruction that leads to airflow limitation and reduced lung function. Although with…”
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Hyperglycemia in Streptozotocin-Induced Diabetic Rat Increases Infarct Size Associated With Low Levels of Myocardial HO-1 During Ischemia/Reperfusion by DI FILIPPO, Clara, MARFELLA, Raffaele, CUZZOCREA, Salvatore, PIEGARI, Elena, PETRONELLA, Pasquale, GIUGLIANO, Dario, ROSSI, Francesco, D'ANDCO, Michele

“…Hyperglycemia in Streptozotocin-Induced Diabetic Rat Increases Infarct Size Associated With Low Levels of Myocardial HO-1 During Ischemia/Reperfusion Clara Di…”
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New Role of Adult Lung c-kit+ Cells in a Mouse Model of Airway Hyperresponsiveness by De Palma, Raffaele, Rossi, Francesco, De Angelis, A., D’Agostino, Bruno, Tartaglione, Gioia, Sgambato, Manuela, Matteis, Maria, Esposito, Grazia, Piegari, Elena, Urbanek, Konrad, Cappetta, Donato, Spaziano, Giuseppe, Russo, Rosa

“…Structural changes contribute to airway hyperresponsiveness and airflow obstruction in asthma. Emerging evidence points to the involvement of c-kit+ cells in…”
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MicroRNA-34a regulates doxorubicin-induced cardiotoxicity in rat by Piegari, Elena, Russo, Rosa, Cappetta, Donato, Esposito, Grazia, Urbanek, Konrad, Dell’Aversana, Carmela, Altucci, Lucia, Berrino, Liberato, Rossi, Francesco, De Angelis, Antonella

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Absence of Inducible Nitric Oxide Synthase Reduces Myocardial Damage During Ischemia Reperfusion in Streptozotocin-Induced Hyperglycemic Mice by MARFELLA, Raffaele, DI FILIPPO, Clara, ESPOSITO, Katherine, NAPPO, Francesco, PIEGARI, Elena, CUZZOCREA, Salvatore, BERRINO, Liberate, ROSSI, Francesco, GIUGLIANO, Dario, D'AMICO, Michele

“…Absence of Inducible Nitric Oxide Synthase Reduces Myocardial Damage During Ischemia Reperfusion in Streptozotocin-Induced Hyperglycemic Mice Raffaele Marfella…”
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Myocardial Strain Analysis in a Doxorubicin-Induced Cardiomyopathy Model by Piegari, Elena, Di Salvo, Giovanni, Castaldi, Biagio, Vitelli, Maria Redenta, Rodolico, Gabriella, Golino, Paolo, Calabrò, Raffaele, Rossi, Francesco, Berrino, Liberato

“…Abstract The aim of our study was to determine if strain (S) and strain rate (SR) imaging are more sensitive indices with respect to standard echocardiographic…”
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Doxorubicin targets multiple players: A new view of an old problem by Cappetta, Donato, Rossi, Francesca, Piegari, Elena, Quaini, Federico, Berrino, Liberato, Urbanek, Konrad, De Angelis, Antonella

“…[Display omitted] Anthracycline cardiotoxicity remains a serious problem in paediatric and adult cancer survivors, and the advancement of cardio-oncology is a…”
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Sitagliptin reduces inflammation, fibrosis and preserves diastolic function in a rat model of heart failure with preserved ejection fraction by Esposito, Grazia, Cappetta, Donato, Russo, Rosa, Rivellino, Alessia, Ciuffreda, Loreta Pia, Roviezzo, Fiorentina, Piegari, Elena, Berrino, Liberato, Rossi, Francesco, De Angelis, Antonella, Urbanek, Konrad

“…Background and Purpose Heart failure with preserved ejection fraction (HFpEF) is a systemic syndrome driven by co‐morbidities, and its pathophysiology is…”
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Effects of ranolazine in a model of doxorubicin‐induced left ventricle diastolic dysfunction by Cappetta, Donato, Esposito, Grazia, Coppini, Raffaele, Piegari, Elena, Russo, Rosa, Ciuffreda, Loreta Pia, Rivellino, Alessia, Santini, Lorenzo, Rafaniello, Concetta, Scavone, Cristina, Rossi, Francesco, Berrino, Liberato, Urbanek, Konrad, De Angelis, Antonella

“…Background and Purpose Doxorubicin is a highly effective anticancer drug, but its clinical application is hampered by cardiotoxicity. Asymptomatic diastolic…”
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RB2/p130 ectopic gene expression in neuroblastoma stem cells: evidence of cell-fate restriction and induction of differentiation by Jori, F P, Galderisi, U, Piegari, E, Peluso, G, Cipollaro, M, Cascino, A, Giordano, A, Melone, M A

“…The activity of the RB2/p130 gene, which is a member of the retinoblastoma gene family, is cell-cycle-regulated and plays a key role in growth inhibition and…”
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Glutamate-induced ATP synthesis: relationship between plasma membrane Na+/Ca2+ exchanger and excitatory amino acid transporters in brain and heart cell models by Magi, Simona, Arcangeli, Sara, Castaldo, Pasqualina, Nasti, Annamaria Assunta, Berrino, Liberato, Piegari, Elena, Bernardini, Renato, Amoroso, Salvatore, Lariccia, Vincenzo

“…It is known that glutamate (Glu), the major excitatory amino acid in the central nervous system, can be an essential source for cell energy metabolism. Here we…”
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SIRT1 activation rescues doxorubicin-induced loss of functional competence of human cardiac progenitor cells by De Angelis, Antonella, Piegari, Elena, Cappetta, Donato, Russo, Rosa, Esposito, Grazia, Ciuffreda, Loreta Pia, Ferraiolo, Fiorella Angelica Valeria, Frati, Caterina, Fagnoni, Francesco, Berrino, Liberato, Quaini, Federico, Rossi, Francesco, Urbanek, Konrad

“…Abstract Background The search for compounds able to counteract chemotherapy-induced heart failure is extremely important at the age of global cancer epidemic…”
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Doxorubicin induces senescence and impairs function of human cardiac progenitor cells by Piegari, Elena, De Angelis, Antonella, Cappetta, Donato, Russo, Rosa, Esposito, Grazia, Costantino, Sarah, Graiani, Gallia, Frati, Caterina, Prezioso, Lucia, Berrino, Liberato, Urbanek, Konrad, Quaini, Federico, Rossi, Francesco

“…The increasing population of cancer survivors faces considerable morbidity and mortality due to late effects of the antineoplastic therapy. Cardiotoxicity is a…”
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Long-term administration of ranolazine attenuates diastolic dysfunction and adverse myocardial remodeling in a model of heart failure with preserved ejection fraction by De Angelis, Antonella, Cappetta, Donato, Piegari, Elena, Rinaldi, Barbara, Ciuffreda, Loreta Pia, Esposito, Grazia, Ferraiolo, Fiorella Angelica Valeria, Rivellino, Alessia, Russo, Rosa, Donniacuo, Maria, Rossi, Francesco, Urbanek, Konrad, Berrino, Liberato

“…Abstract Background To investigate the effects of chronic administration of ranolazine (RAN) on experimental model of heart failure with preserved ejection…”
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