Search Results - "PIEBER, THOMAS"

Vitamin D and immune function by Prietl, Barbara, Treiber, Gerlies, Pieber, Thomas R, Amrein, Karin

“…Vitamin D metabolizing enzymes and vitamin D receptors are present in many cell types including various immune cells such as antigen-presenting-cells, T cells,…”
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Alterations in Gut Microbiome Composition and Barrier Function Are Associated with Reproductive and Metabolic Defects in Women with Polycystic Ovary Syndrome (PCOS): A Pilot Study by Lindheim, Lisa, Bashir, Mina, Münzker, Julia, Trummer, Christian, Zachhuber, Verena, Leber, Bettina, Horvath, Angela, Pieber, Thomas R, Gorkiewicz, Gregor, Stadlbauer, Vanessa, Obermayer-Pietsch, Barbara

“…Polycystic ovary syndrome (PCOS) is a common female endocrinopathy of unclear origin characterized by hyperandrogenism, oligo-/anovulation, and ovarian cysts…”
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Shift to Fatty Substrate Utilization in Response to Sodium-Glucose Cotransporter 2 Inhibition in Subjects Without Diabetes and Patients With Type 2 Diabetes by Ferrannini, Ele, Baldi, Simona, Frascerra, Silvia, Astiarraga, Brenno, Heise, Tim, Bizzotto, Roberto, Mari, Andrea, Pieber, Thomas R, Muscelli, Elza

“…Pharmacologically induced glycosuria elicits adaptive responses in glucose homeostasis and hormone release. In type 2 diabetes (T2D), along with decrements in…”
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A Pooled Analysis of Clinical Pharmacology Trials Investigating the Pharmacokinetic and Pharmacodynamic Characteristics of Fast-Acting Insulin Aspart in Adults with Type 1 Diabetes by Heise, Tim, Pieber, Thomas R., Danne, Thomas, Erichsen, Lars, Haahr, Hanne

“…Background Fast-acting insulin aspart (faster aspart) is insulin aspart (IAsp) in a new formulation aiming to mimic the fast endogenous prandial insulin…”
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Effects of High-Intensity Interval Exercise versus Moderate Continuous Exercise on Glucose Homeostasis and Hormone Response in Patients with Type 1 Diabetes Mellitus Using Novel Ultra-Long-Acting Insulin by Moser, Othmar, Tschakert, Gerhard, Mueller, Alexander, Groeschl, Werner, Pieber, Thomas R, Obermayer-Pietsch, Barbara, Koehler, Gerd, Hofmann, Peter

“…We investigated blood glucose (BG) and hormone response to aerobic high-intensity interval exercise (HIIE) and moderate continuous exercise (CON) matched for…”
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Effect of Oral Semaglutide Compared With Placebo and Subcutaneous Semaglutide on Glycemic Control in Patients With Type 2 Diabetes: A Randomized Clinical Trial by Davies, Melanie, Pieber, Thomas R, Hartoft-Nielsen, Marie-Louise, Hansen, Oluf K. H, Jabbour, Serge, Rosenstock, Julio

“…IMPORTANCE: Glucagon-like peptide-1 (GLP-1) receptor agonists are effective therapies for the treatment of type 2 diabetes and are all currently available as…”
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Empagliflozin in acute myocardial infarction: the EMMY trial by von Lewinski, Dirk, Kolesnik, Ewald, Tripolt, Norbert J, Pferschy, Peter N, Benedikt, Martin, Wallner, Markus, Alber, Hannes, Berger, Rudolf, Lichtenauer, Michael, Saely, Christoph H, Moertl, Deddo, Auersperg, Pia, Reiter, Christian, Rieder, Thomas, Siller-Matula, Jolanta M, Gager, Gloria M, Hasun, Matthias, Weidinger, Franz, Pieber, Thomas R, Zechner, Peter M, Herrmann, Markus, Zirlik, Andreas, Holman, Rury R, Oulhaj, Abderrahim, Sourij, Harald

“…Sodium-glucose co-transporter 2 inhibition reduces the risk of hospitalization for heart failure and for death in patients with symptomatic heart failure…”
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Risk of hypoglycaemia with insulin degludec versus insulin glargine U300 in insulin-treated patients with type 2 diabetes: the randomised, head-to-head CONCLUDE trial by Philis-Tsimikas, Athena, Klonoff, David C., Khunti, Kamlesh, Bajaj, Harpreet S., Leiter, Lawrence A., Hansen, Melissa V., Troelsen, Lone N., Ladelund, Steen, Heller, Simon, Pieber, Thomas R.

“…Aims/hypothesis A head-to-head randomised trial was conducted to evaluate hypoglycaemia safety with insulin degludec 200 U/ml (degludec U200) and insulin…”
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New Insulins, Biosimilars, and Insulin Therapy by Danne, Thomas, Heinemann, Lutz, Pieber, Thomas R

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Assessment of blood-brain barrier function and the neuroinflammatory response in the rat brain by using cerebral open flow microperfusion (cOFM) by Ghosh, Arijit, Birngruber, Thomas, Sattler, Wolfgang, Kroath, Thomas, Ratzer, Maria, Sinner, Frank, Pieber, Thomas R

“…Blood-brain barrier (BBB) impairment in systemic inflammation leads to neuroinflammation. Several factors including cytokines, chemokines and signal…”
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Stratifying nutritional restriction in cancer therapy: Next stop, personalized medicine by Krstic, Jelena, Pieber, Thomas R, Prokesch, Andreas

“…Dietary interventions combined with cancer drugs represent a clinically valid polytherapy. In particular nutrient restriction (NR) in the form of varied…”
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Effects of high doses of vitamin D3 on mucosa-associated gut microbiome vary between regions of the human gastrointestinal tract by Bashir, Mina, Prietl, Barbara, Tauschmann, Martin, Mautner, Selma I., Kump, Patrizia K., Treiber, Gerlies, Wurm, Philipp, Gorkiewicz, Gregor, Högenauer, Christoph, Pieber, Thomas R.

“…Purpose Vitamin D is well known for its effects on bone mineralisation but has also been attributed immunomodulatory properties. It positively influences human…”
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Dasiglucagon: A Next-Generation Glucagon Analog for Rapid and Effective Treatment of Severe Hypoglycemia Results of Phase 3 Randomized Double-Blind Clinical Trial by Pieber, Thomas R, Aronson, Ronnie, Hövelmann, Ulrike, Willard, Julie, Plum-Mörschel, Leona, Knudsen, Kim M, Bandak, Benedikte, Tehranchi, Ramin

“…OBJECTIVE To evaluate the efficacy and safety of dasiglucagon, a ready-to-use, next-generation glucagon analog in aqueous formulation for subcutaneous dosing,…”
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Vitamin D status and arterial hypertension: a systematic review by Pilz, Stefan, Tomaschitz, Andreas, Ritz, Eberhard, Pieber, Thomas R

“…In this extensive Review, Stefan Pilz and colleagues discuss the potential mechanisms by which vitamin D might affect blood pressure and explore the clinical…”
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DEVOTE 3: temporal relationships between severe hypoglycaemia, cardiovascular outcomes and mortality by Pieber, Thomas R., Marso, Steven P., McGuire, Darren K., Zinman, Bernard, Poulter, Neil R., Emerson, Scott S., Pratley, Richard E., Woo, Vincent, Heller, Simon, Lange, Martin, Brown-Frandsen, Kirstine, Moses, Alan, Barner Lekdorf, Jesper, Lehmann, Lucine, Kvist, Kajsa, Buse, John B.

“…Aims/hypothesis The double-blind Trial Comparing Cardiovascular Safety of Insulin Degludec vs Insulin Glargine in Patients with Type 2 Diabetes at High Risk of…”
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Sclerostin and Its Association with Physical Activity, Age, Gender, Body Composition, and Bone Mineral Content in Healthy Adults by Amrein, Karin, Amrein, Steven, Drexler, Camilla, Dimai, Hans Peter, Dobnig, Harald, Pfeifer, Klaus, Tomaschitz, Andreas, Pieber, Thomas R, Fahrleitner-Pammer, Astrid

“…Context: Sclerostin is produced by osteocytes and inhibits bone formation through the Wnt/β-catenin-signaling pathway. Only limited data are available on…”
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Day-to-day fasting glycaemic variability in DEVOTE: associations with severe hypoglycaemia and cardiovascular outcomes (DEVOTE 2) by Zinman, Bernard, Marso, Steven P., Poulter, Neil R., Emerson, Scott S., Pieber, Thomas R., Pratley, Richard E., Lange, Martin, Brown-Frandsen, Kirstine, Moses, Alan, Ocampo Francisco, Ann Marie, Barner Lekdorf, Jesper, Kvist, Kajsa, Buse, John B.

“…Aims/hypothesis The Trial Comparing Cardiovascular Safety of Insulin Degludec vs Insulin Glargine in Patients with Type 2 Diabetes at High Risk of…”
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International Consensus on Risk Management of Diabetic Ketoacidosis in Patients With Type 1 Diabetes Treated With Sodium-Glucose Cotransporter (SGLT) Inhibitors by Danne, Thomas, Garg, Satish, Peters, Anne L, Buse, John B, Mathieu, Chantal, Pettus, Jeremy H, Alexander, Charles M, Battelino, Tadej, Ampudia-Blasco, F Javier, Bode, Bruce W, Cariou, Bertrand, Close, Kelly L, Dandona, Paresh, Dutta, Sanjoy, Ferrannini, Ele, Fourlanos, Spiros, Grunberger, George, Heller, Simon R, Henry, Robert R, Kurian, Martin J, Kushner, Jake A, Oron, Tal, Parkin, Christopher G, Pieber, Thomas R, Rodbard, Helena W, Schatz, Desmond, Skyler, Jay S, Tamborlane, William V, Yokote, Koutaro, Phillip, Moshe

“…Sodium-glucose cotransporter (SGLT) inhibitors are new oral antidiabetes medications shown to effectively reduce glycated hemoglobin (A1C) and glycemic…”
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Vitamin D status and its association with season, hospital and sepsis mortality in critical illness by Amrein, Karin, Zajic, Paul, Schnedl, Christian, Waltensdorfer, Andreas, Fruhwald, Sonja, Holl, Alexander, Purkart, Tadeja, Wünsch, Gerit, Valentin, Thomas, Grisold, Andrea, Stojakovic, Tatjana, Amrein, Steven, Pieber, Thomas R, Dobnig, Harald

“…Vitamin D plays a key role in immune function. Deficiency may aggravate the incidence and outcome of infectious complications in critically ill patients. We…”
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IPO: a tool for automated optimization of XCMS parameters by Libiseller, Gunnar, Dvorzak, Michaela, Kleb, Ulrike, Gander, Edgar, Eisenberg, Tobias, Madeo, Frank, Neumann, Steffen, Trausinger, Gert, Sinner, Frank, Pieber, Thomas, Magnes, Christoph

“…Untargeted metabolomics generates a huge amount of data. Software packages for automated data processing are crucial to successfully process these data. A…”
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